An essential role for retinoid signaling in anteroposterior neural specification and neuronal differentiation

The RXR heterodimers and orphan receptors

1995 • 3,168 citations

A decade of molecular biology of retinoic acid receptors

1996 • 2,893 citations

A human retinoic acid receptor which belongs to the family of nuclear receptors

1987 • 2,245 citations

Identification of a receptor for the morphogen retinoic acid

1987 • 2,007 citations

9-cis retinoic acid is a high affinity ligand for the retinoid X receptor

1992 • 1,790 citations

Nuclear receptor that identifies a novel retinoic acid response pathway

1990 • 1,529 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

9-Cis retinoic acid stereoisomer binds and activates the nuclear receptor RXRα

1992 • 1,252 citations

Characterization of three RXR genes that mediate the action of 9-cis retinoic acid.

1992 • 1,200 citations

Functional inactivation of genes by dominant negative mutations

1987 • 1,174 citations

Patterning the Vertebrate Neuraxis

1996 • 1,151 citations

Identification of a nuclear receptor that is activated by farnesol metabolites

1995 • 1,134 citations

LXR, a nuclear receptor that defines a distinct retinoid response pathway.

1995 • 1,089 citations

Nonsteroid nuclear receptors: What Are genetic studies telling us about their role in real life?

1995 • 1,011 citations

Retinoic acid causes an anteroposterior transformation in the developing central nervous system

1989 • 885 citations

Retinoic acid induces embryonal carcinoma cells to differentiate into neurons and glial cells.

1982 • 791 citations

Transgenic Xenopus embryos from sperm nuclear transplantations reveal FGF signaling requirements during gastrulation

1996 • 789 citations

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

1994 • 759 citations

Regulation of neural induction by the Chd and Bmp-4 antagonistic patterning signals in Xenopus

1995 • 731 citations

Control of muscle and neuronal differentiation in a cultured embryonal carcinoma cell line

1982 • 674 citations

Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta

1995 • 669 citations

The retinoid receptors.

1994 • 665 citations

Unique response pathways are established by allosteric interactions among nuclear hormone receptors

1995 • 629 citations

A novel pathway for vitamin A signaling mediated by RXR heterodimerization with NGFI-B and NURR1.

1995 • 548 citations

Inhibition of activin receptor signaling promotes neuralization in Xenopus

1994 • 484 citations

Exogenous retinoic acid rapidly induces anterior ectopic expression of murine Hox-2 genes in vivo

1992 • 467 citations

Engrailed, Wnt and Pax genes regulate midbrain-hindbrain development

1996 • 440 citations

Fibroblast growth factor is a direct neural inducer, which combined with noggin generates anterior-posterior neural pattern

1995 • 390 citations

Retinoic Acid-Induced Growth Inhibition and Morphologic Differentiation of Human Neuroblastoma Cells In Vitro<xref ref-type="fn" rid="fn2">2</xref>

1982 • 384 citations

Disruption of BMP signals in embryonic Xenopus ectoderm leads to direct neural induction.

1995 • 368 citations

Identification of a retinoic acid-sensitive period during primary axis formation in Xenopus laevis.

1990 • 364 citations

Vitamin A-deficient quail embryos have half a hindbrain and other neural defects

1996 • 335 citations

Caudalization of neural fate by tissue recombination and bFGF

1995 • 290 citations

eFGF, Xcad3 and Hox genes form a molecular pathway that establishes the anteroposterior axis in Xenopus

1996 • 285 citations

The retinoid ligand 4-oxo-retinoic acid is a highly active modulator of positional specification

1993 • 285 citations

SMRT isoforms mediate repression and anti-repression of nuclear receptor heterodimers.

1996 • 244 citations

An essential role for retinoid signaling in anteroposterior neural patterning

1997 • 236 citations

Retinoic acid causes abnormal development and segmental patterning of the anterior hindbrain in Xenopus embryos

1991 • 229 citations

Endogenous distribution of retinoids during normal development and teratogenesis in the mouse embryo

1995 • 229 citations

Retinoic acid and pattern formation in vertebrates

1995 • 223 citations

Specification of the Anteroposterior Neural Axis through Synergistic Interaction of the Wnt Signaling Cascade withnogginandfollistatin

1995 • 222 citations

Retinoic acid modifies mesodermal patterning in early Xenopus embryos.

1991 • 221 citations

bFGF as a possible morphogen for the anteroposterior axis of the central nervous system in Xenopus

1995 • 203 citations

Differential activation of Xenopus homeo box genes by mesoderm-inducing growth factors and retinoic acid.

1990 • 199 citations

Retinoic acid modifies development of the midbrain-hindbrain border and affects cranial ganglion formation in zebrafish embryos

1991 • 188 citations

Intracellular Signaling by 14-hydroxy-4,14- Retro -Retinol

1991 • 184 citations

Activation and organization of the central nervous system in amphibians. Part III. Synthesis of a new working hypothesis

1952 • 180 citations

Synergistic Activation of Retinoic Acid (RA)-Responsive Genes and Induction of Embryonal Carcinoma Cell Differentiation by an RA Receptor α (RARα)-, RARβ-, or RARγ-Selective Ligand in Combination with a Retinoid X Receptor-Specific Ligand

1995 • 180 citations

Expression of Pax-3 is initiated in the early neural plate by posteriorizing signals produced by the organizer and by posterior non-axial mesoderm

1997 • 172 citations

Retinoid X Receptor (RXR) within the RXR-Retinoic Acid Receptor Heterodimer Binds Its Ligand and Enhances Retinoid-Dependent Gene Expression

1997 • 167 citations

Activation of specific RXR heterodimers by an antagonist of RXR homodimers

1996 • 164 citations

Retinoic acid perturbs the expression of Xhox.lab genes and alters mesodermal determination in Xenopus laevis.

1991 • 163 citations

Retinoic acid induces stage-specific antero-posterior transformation of rostral central nervous system

1995 • 158 citations

The Retinoids: Biology, Chemistry and Medicine, 2nd ed

1994 • 156 citations

A posteriorising factor, retinoic acid, reveals that anteroposterior patterning controls the timing of neuronal differentiation in Xenopus neuroectoderm

1996 • 152 citations

Basic FGF as an inducer of anteroposterior neural pattern

1995 • 145 citations

A Concentration Gradient of Retinoids in the Early Xenopus laevis Embryo

1994 • 133 citations

Retinoic acid signaling is required during early chick limb development

1996 • 132 citations

The phantom ligand effect: allosteric control of transcription by the retinoid X receptor.

1997 • 128 citations

Retinoic acid is enriched in Hensen's node and is developmentally regulated in the early chicken embryo.

1992 • 122 citations

4-Oxoretinol, a new natural ligand and transactivator of the retinoic acid receptors.

1996 • 115 citations

Regulation of the Xenopus labial Homeodomain Genes, HoxA1 and HoxD1: Activation by Retinoids and Peptide Growth Factors

1995 • 112 citations

Identification and Functional Separation of Retinoic Acid Receptor Neutral Antagonists and Inverse Agonists

1996 • 110 citations

Endogenous retinoids in the zebrafish embryo and adult

1996 • 107 citations

The retinoid X receptor ligand, 9-cis-retinoic acid, is a potential regulator of early Xenopus development.

1994 • 106 citations

Retinoic acid can mimic endogenous signals involved in transformation of the xenopus nervous system

1991 • 92 citations

Dynamic aspects of neural induction in amphibia.

1954 • 89 citations

v-erbA and citral reduce the teratogenic effects of all-trans retinoic acid and retinol, respectively, in Xenopus embryogenesis

1993 • 87 citations

Spemann's organizer: models and molecules

1993 • 78 citations

Retinoid receptors promote primary neurogenesis in Xenopus

1997 • 78 citations

Transcription factors and head formation in vertebrates

1997 • 60 citations

Caudalization by the amphibian organizer: brachyury, convergent extension and retinoic acid

1994 • 58 citations

Identification of a domain required for oncogenic activity and transcriptional suppression by v-erbA and thyroid-hormone receptor alpha.

1993 • 54 citations

The Receptor-DNA Complex Determines the Retinoid Response: a Mechanism for the Diversification of the Ligand Signal

1996 • 45 citations

COUP-TFI is a potential regulator of retinoic acid-modulated development in Xenopus embryos

1995 • 31 citations

Differential effects of retinoic acid and a retinoid antagonist on the spatial distribution of the homeoprotein Hoxb‐7 in vertebrate embryos

1995 • 29 citations

Effects of Localized Application of Retinoic Acid on Xenopus laevis Development

1994 • 26 citations

Thyroid Hormone Receptor Can Modulate Retinoic Acid-Mediated Axis Formation in Frog Embryogenesis

1993 • 22 citations

Expression of a dominant negative retinoic acid receptor ? in Xenopus embryos leads to partial resistance to retinoic acid

1994 • 13 citations