Reelin Binds α3β1 Integrin and Inhibits Neuronal Migration

A protein related to extracellular matrix proteins deleted in the mouse mutant reeler

1995 • 1,720 citations

Reeler/Disabled-like Disruption of Neuronal Migration in Knockout Mice Lacking the VLDL Receptor and ApoE Receptor 2

1999 • 1,231 citations

Glutamate toxicity in a neuronal cell line involves inhibition of cystine transport leading to oxidative stress

1989 • 987 citations

NPXY, a sequence often found in cytoplasmic tails, is required for coated pit-mediated internalization of the low density lipoprotein receptor.

1990 • 944 citations

Direct Binding of Reelin to VLDL Receptor and ApoE Receptor 2 Induces Tyrosine Phosphorylation of Disabled-1 and Modulates Tau Phosphorylation

1999 • 902 citations

The reeler gene-associated antigen on cajal-retzius neurons is a crucial molecule for laminar organization of cortical neurons

1995 • 882 citations

Mutations in filamin 1 Prevent Migration of Cerebral Cortical Neurons in Human Periventricular Heterotopia

1998 • 858 citations

CENTRAL NERVOUS SYSTEM NEURONAL MIGRATION

1999 • 808 citations

Reelin Is a Ligand for Lipoprotein Receptors

1999 • 803 citations

Neuronal position in the developing brain is regulated by mouse disabled-1

1997 • 698 citations

Scrambler and yotari disrupt the disabled gene and produce a reeler -like phenotype in mice

1997 • 637 citations

Interaction of Cytosolic Adaptor Proteins with Neuronal Apolipoprotein E Receptors and the Amyloid Precursor Protein

1998 • 544 citations

Reelin Is a Secreted Glycoprotein Recognized by the CR-50 Monoclonal Antibody

1997 • 512 citations

Time of origin of corresponding cell classes in the cerebral cortex of normal and reeler mutant mice: An autoradiographic analysis

1973 • 412 citations

Reelin-induced tryosine phosphorylation of Disabled 1 during neuronal positioning

1999 • 407 citations

α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane

1997 • 407 citations

The Disabled 1 Phosphotyrosine-Binding Domain Binds to the Internalization Signals of Transmembrane Glycoproteins and to Phospholipids

1999 • 381 citations

Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain

1998 • 370 citations

Distinct Functions of α3 and αV Integrin Receptors in Neuronal Migration and Laminar Organization of the Cerebral Cortex

1999 • 344 citations

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development

1997 • 337 citations

Integrin cytoplasmic tyrosine motif is required for outside-in αIIbβ3 signalling and platelet function

1999 • 315 citations

Essential role of α6 integrins in cortical and retinal lamination

1998 • 301 citations

Characterization of the integrin alpha v beta 6 as a fibronectin-binding protein.

1992 • 292 citations

Proteins of the CNR Family Are Multiple Receptors for Reelin

1999 • 276 citations

RAP, a specialized chaperone, prevents ligand-induced ER retention and degradation of LDL receptor-related endocytic receptors.

1996 • 274 citations

Orchestration of neuronal migration by activity of ion channels, neurotransmitter receptors, and intracellular Ca2+ fluctuations

1998 • 269 citations

Aberrant Splicing of a Mouse disabled Homolog, mdab1, in the scrambler Mouse

1997 • 263 citations

Posttranslational processing of the LDL receptor and its genetic disruption in familial hypercholesterolemia

1982 • 245 citations

Obstructed neuronal migration along radial glial fibers in the neocortex of the reeler mouse: A golgi-EM analysis

1982 • 240 citations

Involvement of Receptor-like Protein Tyrosine Phosphatase ζ/RPTPβ and Its Ligand Pleiotrophin/Heparin-binding Growth-associated Molecule (HB-GAM) in Neuronal Migration

1998 • 219 citations

Novel Roles for α3β1 Integrin as a Regulator of Cytoskeletal Assembly and as a Trans-dominant Inhibitor of Integrin Receptor Function in Mouse Keratinocytes

1998 • 207 citations

Ligand-induced changes in integrin expression regulate neuronal adhesion and neurite outgrowth

1997 • 193 citations

Disabled-1 Binds to the Cytoplasmic Domain of Amyloid Precursor-Like Protein 1

1999 • 188 citations

Regulation of Purkinje Cell Alignment by Reelin as Revealed with CR-50 Antibody

1997 • 178 citations

Identification of integrin α3β1 as a neuronal thrombospondin receptor mediating neurite outgrowth

1995 • 166 citations

Reelin, the Extracellular Matrix Protein Deficient in Reeler Mutant Mice, Is Processed by a Metalloproteinase

1999 • 156 citations

Genetic Malformations of the Human Cerebral Cortex

1999 • 152 citations

Retrovirally introduced antisense integrin RNA inhibits neuroblast migration in vivo

1992 • 151 citations

Birthdate and Cell Marker Analysis of Scrambler: A Novel Mutation Affecting Cortical Development with a Reeler-Like Phenotype

1997 • 114 citations

Multiple receptor systems promote CNS neural migration

1993 • 97 citations

Detection of the reelin breakpoint in reeler mice

1996 • 95 citations

The mouse mutation reeler causes increased adhesion within a subpopulation of early postmitotic cortical neurons

1995 • 93 citations

Extracellular matrix and neuronal movement

1990 • 92 citations

Nerve Growth Factor Stimulates the Accumulation of β1 Integrin at the Tips of Filopodia in the Growth Cones of Sympathetic Neurons

1997 • 92 citations

Kinetic and morphological evidence for endocytosis of mammalian cell integrin receptors by using an anti-fibronectin receptor β subunit monoclonal antibody

1989 • 54 citations

Retroviral transfer of antisense integrin alpha6 or alpha8 sequences results in laminar redistribution or clonal cell death in developing brain.

1998 • 49 citations

Retroviral Transfer of Antisense Integrin α6 or α8 Sequences Results in Laminar Redistribution or Clonal Cell Death in Developing Brain

1998 • 42 citations

β1 integrin deficiency impairs migration and differentiation of mouse embryonic stem cell derived neurons

1998 • 39 citations

The identification of seven metalloproteinase-disintegrin (ADAM) genes from genomic libraries

1999 • 39 citations

Identification and distribution of proteins in isolated endosomal fractions of rat liver: involvement in endocytosis, recycling and transcytosis

1997 • 39 citations

Surface and cytoskeletal markers of rostrocaudal position in the mammalian nervous system

1993 • 32 citations

Synthesis and properties of the very-low-density-lipoprotein receptor and a comparison with the low-density-lipoprotein receptor

1997 • 20 citations

Identification and characterization of a novel high-molecular-weight form of the integrin α3 subunit

1992 • 12 citations