Synthesis and properties of the very-low-density-lipoprotein receptor and a comparison with the low-density-lipoprotein receptor

Binding and Degradation of Low Density Lipoproteins by Cultured Human Fibroblasts

1974 • 1,481 citations

The LDL Receptor Gene: A Mosaic of Exons Shared with Different Proteins

1985 • 845 citations

Immunogenic structure of the influenza virus hemagglutinin

1982 • 759 citations

Release of low density lipoprotein from its cell surface receptor by sulfated glycosaminoglycans

1976 • 618 citations

Rabbit very low density lipoprotein receptor: a low density lipoprotein receptor-like protein with distinct ligand specificity.

1992 • 548 citations

Domain map of the LDL receptor: Sequence homology with the epidermal growth factor precursor

1984 • 377 citations

Biosynthesis of N- and O-linked oligosaccharides of the low density lipoprotein receptor.

1983 • 369 citations

Different combinations of cysteine-rich repeats mediate binding of low density lipoprotein receptor to two different proteins

1989 • 307 citations

Mutational analysis of the ligand binding domain of the low density lipoprotein receptor.

1988 • 281 citations

Structure, chromosome location, and expression of the human very low density lipoprotein receptor gene.

1994 • 266 citations

Normal plasma lipoproteins and fertility in gene-targeted mice homozygous for a disruption in the gene encoding very low density lipoprotein receptor.

1995 • 259 citations

Chicken oocyte growth is mediated by an eight ligand binding repeat member of the LDL receptor family.

1994 • 241 citations

Effective treatment of familial hypercholesterolaemia in the mouse model using adenovirus–mediated transfer of the VLDL receptor gene

1996 • 179 citations

Deletion of clustered O-linked carbohydrates does not impair function of low density lipoprotein receptor in transfected fibroblasts.

1986 • 177 citations

Reversal of Hypercholesterolemia in Low Density Lipoprotein Receptor Knockout Mice by Adenovirus-mediated Gene Transfer of the Very Low Density Lipoprotein Receptor

1996 • 129 citations

Characterization and tissue-specific expression of the human ‘very low density lipoprotein (VLDL) receptor’ mRNA

1994 • 129 citations

Regulation of the very low density lipoprotein receptor by thyroid hormone in rat skeletal muscle

1994 • 127 citations

Mutant oocytic low density lipoprotein receptor gene family member causes atherosclerosis and female sterility.

1995 • 117 citations

Self-association of the low density lipoprotein receptor mediated by the cytoplasmic domain.

1987 • 99 citations

Hormonal regulation of low‐density lipoprotein (LDL) receptor activity in human hepatoma Hep G2 cells

1988 • 95 citations

Lipid Accumulation and Foam Cell Formation in Chinese Hamster Ovary Cells Overexpressing Very Low Density Lipoprotein Receptor

1995 • 49 citations

New variant of low density lipoprotein receptor gene. FH-Tonami.

1988 • 46 citations

Deletion of exon 15 of the LDL receptor gene is associated with a mild form of familial hypercholesterolemia. FH-Espoo.

1993 • 45 citations

Measurement OF Human venous plasma prostacyclin and metabolites by radioimmunoassay: A reappraisal

1983 • 30 citations

Immunoprecipitation of the low-density-lipoprotein (LDL) receptor and its precursor from human monocyte-derived macrophages

1986 • 22 citations

Defective processing and binding of low‐density lipoprotein receptors in fibroblasts from a familial hypercholesterolaemic subject

1989 • 20 citations

Degradation of lipoproteins by human monocyte-derived macrophages. Evidence for two distinct processes for the degradation of abnormal very-low-density lipoprotein from subjects with type III hyperlipidaemia

1984 • 18 citations

Regulation of synthesis and cell content of the low‐density‐lipoprotein receptor protein in cultured fibroblasts from normal and familial hypercholesterolaemic subjects

1987 • 16 citations

An antibody to the low‐density lipoprotein (LDL) receptor that partially inhibits the binding of LDL to cultured human fibroblasts

1988 • 11 citations

A mutation and an antibody that affect chemical cross-linking of low-density lipoprotein receptors on human fibroblasts

1993 • 9 citations

Non-saturable degradation of LDL by monocyte-derived macrophages leads to a reduction in HMG-CoA reductase activity with little synthesis of cholesteryl esters

1987 • 8 citations

Abnormal structure and co-operative binding of low-density lipoprotein receptors containing the Glu-80 → Lys mutation

1995 • 5 citations