Mutations in filamin 1 Prevent Migration of Cerebral Cortical Neurons in Human Periventricular Heterotopia

RNA splice junctions of different classes of eukaryotes: sequence statistics and functional implications in gene expression

1987 • 2,333 citations

Isolation of a Miller–Dicker lissencephaly gene containing G protein β-subunit-like repeats

1993 • 1,067 citations

doublecortin, a Brain-Specific Gene Mutated in Human X-Linked Lissencephaly and Double Cortex Syndrome, Encodes a Putative Signaling Protein

1998 • 1,019 citations

Catalytic specificity of protein-tyrosine kinases is critical for selective signalling

1995 • 929 citations

Targeted disruption of the cyclin-dependent kinase 5 gene results in abnormal corticogenesis, neuronal pathology and perinatal death.

1996 • 901 citations

A Novel CNS Gene Required for Neuronal Migration and Involved in X-Linked Subcortical Laminar Heterotopia and Lissencephaly Syndrome

1998 • 740 citations

Mice Lacking p35, a Neuronal Specific Activator of Cdk5, Display Cortical Lamination Defects, Seizures, and Adult Lethality

1997 • 727 citations

Actin-Binding Protein Requirement for Cortical Stability and Efficient Locomotion

1992 • 567 citations

Determination of the Specific Substrate Sequence Motifs of Protein Kinase C Isozymes

1997 • 557 citations

cAMP-Dependent Growth Cone Guidance by Netrin-1

1997 • 550 citations

Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring.

1990 • 522 citations

Mechanisms of actin rearrangements mediating platelet activation.

1992 • 413 citations

Time of origin of corresponding cell classes in the cerebral cortex of normal and reeler mutant mice: An autoradiographic analysis

1973 • 412 citations

Identification of a Mouse p21Cdc42/Rac Activated Kinase

1995 • 395 citations

Isolation and properties of actin, myosin, and a new actinbinding protein in rabbit alveolar macrophages.

1975 • 388 citations

Disabled-1 acts downstream of Reelin in a signaling pathway that controls laminar organization in the mammalian brain

1998 • 370 citations

Recognition and specificity in protein tyrosine kinase-mediated signalling

1995 • 367 citations

Fatal embryonic bleeding events in mice lacking tissue factor, the cell-associated initiator of blood coagulation.

1996 • 340 citations

Mouse disabled (mDab1): a Src binding protein implicated in neuronal development

1997 • 337 citations

Mutations in GDI1 are responsible for X-linked non-specific mental retardation

1998 • 327 citations

Filamin, a new high-molecular-weight protein found in smooth muscle and non-muscle cells.

1975 • 317 citations

A Role for Tissue Factor in Cell Adhesion and Migration Mediated by Interaction with Actin-binding Protein 280

1998 • 313 citations

Periventricular Heterotopia: An X-Linked Dominant Epilepsy Locus Causing Aberrant Cerebral Cortical Development

1996 • 301 citations

Integrin β Cytoplasmic Domains Differentially Bind to Cytoskeletal Proteins

1998 • 282 citations

The Role of Actin-binding Protein 280 in Integrin-dependent Mechanoprotection

1998 • 258 citations

Direct interaction of filamin (ABP-280) with the beta 2-integrin subunit CD18.

1995 • 252 citations

Distribution and possible interactions of actin-associated proteins and cell adhesion molecules of nerve growth cones

1989 • 196 citations

The architecture of actin filaments and the ultrastructural location of actin-binding protein in the periphery of lung macrophages.

1986 • 196 citations

Filamin Binds to the Cytoplasmic Domain of the β1-Integrin

1998 • 193 citations

Distribution of actin-binding protein and myosin in macrophages during spreading and phagocytosis.

1980 • 175 citations

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.

1996 • 170 citations

Actin-biding Protein-280 Binds the Stress-activated Protein Kinase (SAPK) Activator SEK-1 and Is Required for Tumor Necrosis Factor-α Activation of SAPK in Melanoma Cells

1997 • 169 citations

On the association of glycoprotein Ib and actin-binding protein in human platelets.

1985 • 165 citations

Identification of a membrane skeleton in platelets.

1988 • 161 citations

Actin-binding protein promotes the bipolar and perpendicular branching of actin filaments.

1980 • 156 citations

Periventricular heterotopia and epilepsy

1994 • 155 citations

Emerin deletion reveals a common X-chromosome inversion mediated by inverted repeats

1997 • 154 citations

Actin crosslinking proteins at the leading edge

1994 • 128 citations

Interaction of Presenilins with the Filamin Family of Actin-Binding Proteins

1998 • 125 citations

Birthdate and Cell Marker Analysis of Scrambler: A Novel Mutation Affecting Cortical Development with a Reeler-Like Phenotype

1997 • 114 citations

Properties of the 120,000- and 95,000-dalton actin-binding proteins from Dictyostelium discoideum and their possible functions in assembling the cytoplasmic matrix.

1984 • 107 citations

An activity-dependent network of interactions links the Rel protein Dorsal with its cytoplasmic regulators

1997 • 102 citations

Nonsense mutation in the glycoprotein Ib alpha coding sequence associated with Bernard-Soulier syndrome.

1990 • 95 citations

Identification of the Region in Actin-binding Protein that Binds to the Cytoplasmic Domain of Glycoprotein Ibä

1997 • 90 citations

Identification of a Duplication of Xq28 Associated with Bilateral Periventricular Nodular Heterotopia

1997 • 83 citations

Mapping of two genes encoding isoforms of the actin binding protein ABP-280, a dystrophin like protein, to Xq28 and to chromosome 7

1993 • 76 citations

Actin Filament Crosslinking by Chicken Gizzard Filamin Is Regulated by Phosphorylation in Vitro

1995 • 69 citations

Re-expression of ABP-120 rescues cytoskeletal, motility, and phagocytosis defects of ABP-120- Dictyostelium mutants.

1996 • 65 citations

construction of a transcription map of a 300 kb region around the human G6PD locus by direst cDNA selection

1993 • 53 citations

Clonal X-inactivation analysis of human tumours using the human androgen receptor gene (HUMARA) polymorphism: a non-radioactive and semiquantitative strategy applicable to fresh and archival tissue

1997 • 50 citations

Filamin translocation is an early endothelial cell inflammatory response to bradykinin: regulation by calcium, protein kinases, and protein phosphatases.

1996 • 46 citations

Mayo Clinic Cardiology Review

1999 • 42 citations

Filamin translocation is an early endothelial cell inflammatory response to bradykinin: Regulation by calcium, protein kinases, and protein phosphatases

1996 • 36 citations

The Exon-Intron Organization of the Human X-Linked Gene (FLN1) Encoding Actin-Binding Protein 280

1994 • 31 citations

Emerin Deletions Occurring on Both Xq28 Inversion Backgrounds

1998 • 31 citations

Transcriptional analysis of the candidate region for incontinentia pigmenti (IP2) in Xq28.

1996 • 22 citations

DGGE polymorphism in intron 10 of MSH2, the HNPCC gene

1994 • 15 citations

Mayo Clinic Cardiology Review

1998 • 8 citations

Dinucleotide repeat polymorphism at the human biglycan (BGN) locus

1994 • 4 citations