High Mobility Group B Proteins Facilitate Strong Estrogen Receptor Binding to Classical and Half-Site Estrogen Response Elements and Relax Binding Selectivity

The nuclear receptor superfamily: The second decade

1995 • 6,929 citations

Release of chromatin protein HMGB1 by necrotic cells triggers inflammation

2002 • 4,011 citations

Crystallographic analysis of the interaction of the glucocorticoid receptor with DNA

1991 • 1,501 citations

Combinatorial Control of Gene Expression by Nuclear Receptors and Coregulators

2002 • 1,449 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

Estrogen receptor interaction with estrogen response elements

2001 • 1,031 citations

Estrogen receptor pathways to AP-1

2000 • 867 citations

Regulation of DNA-Dependent Activities by the Functional Motifs of the High-Mobility-Group Chromosomal Proteins

1999 • 837 citations

TRANSCRIPTIONAL REGULATION BY cAMP AND ITS RECEPTOR PROTEIN

1993 • 819 citations

The Glucocorticoid Receptor: Rapid Exchange with Regulatory Sites in Living Cells

2000 • 791 citations

The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: How receptors discriminate between their response elements

1993 • 745 citations

Steroid Hormone Receptors: Interaction with Deoxyribonucleic Acid and Transcription Factors*

1993 • 724 citations

The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements

1988 • 679 citations

Structural determinants of nuclear receptor assembly on DNA direct repeats

1995 • 561 citations

Recognition of a DNA Operator by the Repressor of Phage 434: A View at High Resolution

1988 • 531 citations

Allosteric effects of DNA on transcriptional regulators

1998 • 488 citations

Activation of the ovalbumin gene by the estrogen receptor involves the Fos-Jun complex

1990 • 486 citations

Solution structure of the DMA-binding domain of the oestrogen receptor

1990 • 458 citations

What determines the specificity of action of Drosophila homeodomain proteins?

1990 • 357 citations

High-Mobility Group Chromatin Proteins 1 and 2 Functionally Interact with Steroid Hormone Receptors To Enhance Their DNA Binding In Vitro and Transcriptional Activity in Mammalian Cells

1998 • 338 citations

High mobility group protein-1 (HMG-1) is a unique activator of p53

1998 • 316 citations

On the specificity of DNA-protein interactions.

1986 • 308 citations

A far upstream estrogen response element of the ovalbumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically

1992 • 290 citations

Nuclear-receptor interactions on DNA-response elements

2001 • 280 citations

Sequence homologies in the region preceding the transcription initiation site of the liver estrogen-responsive vitellogenin and apo-VLDLII genes

1984 • 261 citations

Modular structure of transcription factors: Implications for gene regulation

1991 • 260 citations

The molecular actions of thyroid hormone in bone

2003 • 252 citations

The DNA chaperone HMGB1 facilitates ACF/CHRAC-dependent nucleosome sliding

2002 • 247 citations

The human oxytocin gene promoter is regulated by estrogens.

1990 • 241 citations

HMG1 interacts with HOX proteins and enhances their DNA binding and transcriptional activation.

1996 • 230 citations

High mobility group protein 2 functionally interacts with the POU domains of octamer transcription factors.

1995 • 224 citations

Sequence Requirements for Estrogen Receptor Binding to Estrogen Response Elements

1998 • 205 citations

Steroid hormones induce HMG1 overexpression and sensitize breast cancer cells to cisplatin and carboplatin

2000 • 202 citations

The DNA-Bending Protein HMG-1 Enhances Progesterone Receptor Binding to Its Target DNA Sequences

1994 • 200 citations

Diversity in the mechanisms of gene regulation by estrogen receptors

2002 • 193 citations

HMGB1 inhibits cell death in yeast and mammalian cells and is abundantly expressed in human breast carcinoma

2003 • 191 citations

Cooperative binding of estrogen receptor to imperfect estrogen-responsive DNA elements correlates with their synergistic hormone-dependent enhancer activity.

1989 • 180 citations

The high mobility group protein HMG1 can reversibly inhibit class II gene transcription by interaction with the TATA-binding protein.

1994 • 174 citations

Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter.

1988 • 171 citations

Widely Spaced, Directly Repeated PuGGTCA Elements Act as Promiscuous Enhancers for Different Classes of Nuclear Receptors

1995 • 167 citations

The role of coactivators and corepressors in the biology and mechanism of action of steroid hormone receptors.

2000 • 144 citations

EcoRV restriction endonuclease binds all DNA sequences with equal affinity

1991 • 139 citations

Synergistic activation of transcription by the human estrogen receptor bound to tandem responsive elements.

1990 • 134 citations

Defining a minimal estrogen receptor DNA binding domain

1993 • 124 citations

Estrogen and Thyroid Hormone Receptor Interactions: Physiological Flexibility by Molecular Specificity

2002 • 121 citations

Allosteric Modulation of Estrogen Receptor Conformation by Different Estrogen Response Elements

2001 • 113 citations

Estrogen Response Elements Function as Allosteric Modulators of Estrogen Receptor Conformation

1998 • 110 citations

The basis for half-site specificity explored through a non-cognate steroid receptor-DNA complex

1995 • 107 citations

Monomeric Complex of Human Orphan Estrogen Related Receptor-2 with DNA: A Pseudo-dimer Interface Mediates Extended Half-site Recognition

2003 • 105 citations

The Uteroglobin Promoter Contains a Noncanonical Estrogen Responsive Element

1990 • 98 citations

Novel estrogen response elements identified by genetic selection in yeast are differentially responsive to estrogens and antiestrogens in mammalian cells.

1994 • 92 citations

HMG-1 Stimulates Estrogen Response Element Binding by Estrogen Receptor from Stably Transfected HeLa Cells

1999 • 91 citations

Function of Directly Repeated Half-sites as Response Elements for Steroid Hormone Receptors

1996 • 91 citations

The oestrogen receptor recognizes an imperfectly palindromic response element through an alternative side-chain conformation

1995 • 89 citations

The Phage 434 OR2/R1-69 Complex at 2·5 Å Resolution

1993 • 87 citations

The DNA Architectural Protein HMGB1 Displays Two Distinct Modes of Action That Promote Enhanceosome Assembly

2002 • 84 citations

Binding of hormone accelerates the kinetics of glucocorticoid and progesterone receptor binding to DNA.

1989 • 84 citations

Conservation of Digestive Enzymes

2002 • 84 citations

The Binding Interaction of HMG-1 with the TATA-binding Protein/TATA Complex

2001 • 83 citations

Coregulatory proteins in steroid hormone receptor action:

1999 • 80 citations

Interactions between an HMG-1 protein and members of the Rel family

1999 • 77 citations

Cooperative estrogen receptor interaction with consensus or variant estrogen responsive elements in vitro.

1992 • 73 citations

High-Mobility Group (HMG) Protein HMG-1 and TATA-Binding Protein-Associated Factor TAF_II30 Affect Estrogen Receptor-Mediated Transcriptional Activation

1997 • 70 citations

Phage Display Screening Reveals an Association Between Germline-specific Transcription Factor Oct-4 and Multiple Cellular Proteins

2000 • 65 citations

The Role of the C-terminal Extension (CTE) of the Estrogen Receptor α and β DNA Binding Domain in DNA Binding and Interaction with HMGB

2004 • 62 citations

The High Mobility Group Protein 1 Enhances Binding of the Estrogen Receptor DNA Binding Domain to the Estrogen Response Element

1998 • 59 citations

Regulation of the estrogen-responsive pS2 gene in MCF-7 human breast cancer cells

2000 • 59 citations

The C-terminal Extension (CTE) of the Nuclear Hormone Receptor DNA Binding Domain Determines Interactions and Functional Response to the HMGB-1/-2 Co-regulatory Proteins

2002 • 58 citations

HMG Proteins and DNA Flexibility in Transcription Activation

2001 • 53 citations

Harnessing the writhe: a role for DNA chaperonesin nucleoprotein- complex formation

1994 • 51 citations

Estradiol inhibits glucocorticoid receptor expression and induces glucocorticoid resistance in MCF-7 human breast cancer cells

2001 • 46 citations

Estrogen Receptor α Interaction with Estrogen Response Element Half-Sites from the Rat Prolactin Gene

2000 • 38 citations

Lac repressor—operator complex

1997 • 37 citations

Estrogen Treatment Induces Elevated Expression of HMG1 in MCF-7 Cells

1998 • 34 citations

Interactions between an HMG-4 protein and members of the Rel family

1999 • 30 citations

Regulation of the expression of HMG1, a co-activator of the estrogen receptor.

2001 • 18 citations