Cooperative binding of estrogen receptor to imperfect estrogen-responsive DNA elements correlates with their synergistic hormone-dependent enhancer activity.

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Lipofection: a highly efficient, lipid-mediated DNA-transfection procedure.

1987 • 4,937 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis

1981 • 2,828 citations

Human oestrogen receptor cDNA: sequence, expression and homology to v-erb-A

1986 • 2,341 citations

DNAase footprinting a simple method for the detection of protein-DNA binding specificity

1978 • 2,092 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Transformation of mammalian cells with genes from procaryotes and eucaryotes

1979 • 1,474 citations

Functional domains of the human estrogen receptor

1987 • 1,316 citations

The estrogen receptor binds tightly to its responsive element as a ligand-induced homodimer

1988 • 1,233 citations

Nuclear receptors enhance our understanding of transcription regulation

1988 • 1,062 citations

Isolation of transcription factors that discriminate between different promoters recognized by RNA polymerase II

1983 • 779 citations

Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene

1987 • 760 citations

The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements

1988 • 679 citations

Molecular interactions of steroid hormone receptor with its enhancer element: Evidence for receptor dimer formation

1988 • 600 citations

Many Transcription Factors Interact Synergistically with Steroid Receptors

1988 • 517 citations

Immunochemical studies of estrogen receptors

1984 • 439 citations

A 13 bp palindrome is a functional estrogen responsive element and interacts specifically with estrogen receptor

1988 • 439 citations

Synergistic action of the glucocorticoid receptor with transcription factors.

1988 • 407 citations

A DNA sequence of 15 base pairs is sufficient to mediate both glucocorticoid and progesterone induction of gene expression.

1987 • 360 citations

Oestrogen and glucocorticoid responsive elements are closely related but distinct

1987 • 353 citations

Cooperative binding of steroid hormone receptors contributes to transcriptional synergism at target enhancer elements

1989 • 270 citations

The estrogen-responsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element.

1987 • 268 citations

Sequence homologies in the region preceding the transcription initiation site of the liver estrogen-responsive vitellogenin and apo-VLDLII genes

1984 • 261 citations

Several distinct "CCAAT" box binding proteins coexist in eukaryotic cells.

1988 • 230 citations

Specific binding of estrogen receptor to the estrogen response element.

1989 • 199 citations

DNA sequences outside the receptor-binding sites differently modulate the responsiveness of the mouse mammary tumour virus promoter to various steroid hormones.

1988 • 184 citations

Cell-specific activity of a GGTCA half-palindromic oestrogen-responsive element in the chicken ovalbumin gene promoter.

1988 • 171 citations

TheXenopus laevisEstrogen Receptor: Sequence Homology with Human and Avian Receptors and Identification of Multiple Estrogen Receptor Messenger Ribonucleic Acids*

1987 • 159 citations

Biology and mode of action of pure antioestrogens.

1988 • 149 citations

Glucocorticoid receptor binds cooperatively to adjacent recognition sites.

1989 • 142 citations

Molecular Model of the Interaction Between the Glucocorticoid Receptor and the Regulatory Elements of Inducible Genes

1986 • 117 citations

Vaccinia virus induces cellular mRNA degradation

1983 • 109 citations

Synergism of closely adjacent estrogen-responsive elements increases their regulatory potential

1988 • 105 citations

Plasmids for the cloning and expresion of full-length double-stranded cDNAs under control of the SV40 early or late gene promoter

1983 • 84 citations

Specific Binding of Estrogen Receptor to the Estrogen Response Element

1989 • 50 citations

Inhibition of 40S–Met–tRNAfMet ribosomal initiation complex formation by vaccinia virus

1980 • 33 citations

The human estrogen receptor can regulate exogenous but not endogenous vitellogenin gene promoters in aXenopuscell line

1988 • 28 citations