Chromosome positioning in the interphase nucleus

The language of covalent histone modifications

2000 • 8,260 citations

Cytogenetic analysis using quantitative, high-sensitivity, fluorescence hybridization.

1986 • 3,231 citations

Chromosome territories, nuclear architecture and gene regulation in mammalian cells

2001 • 2,239 citations

Meiotic Chromosomes: Integrating Structure and Function

1999 • 1,250 citations

Differences in the Localization and Morphology of Chromosomes in the Human Nucleus

1999 • 902 citations

Replicon Clusters Are Stable Units of Chromosome Structure: Evidence That Nuclear Organization Contributes to the Efficient Activation and Propagation of S Phase in Human Cells

1998 • 815 citations

Association of Transcriptionally Silent Genes with Ikaros Complexes at Centromeric Heterochromatin

1997 • 792 citations

Orchestrated response: a symphony of transcription factors for gene control

2000 • 763 citations

The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells

2001 • 673 citations

Protein Dynamics: Implications for Nuclear Architecture and Gene Expression

2001 • 664 citations

Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster

1986 • 587 citations

Nuclear lamins: building blocks of nuclear architecture

2002 • 574 citations

Chromatin Motion Is Constrained by Association with Nuclear Compartments in Human Cells

2002 • 572 citations

Perinuclear localization of chromatin facilitates transcriptional silencing

1998 • 466 citations

Proximity of Chromosomal Loci That Participate in Radiation-Induced Rearrangements in Human Cells

2000 • 457 citations

Chromosome Dynamics in the Yeast Interphase Nucleus

2001 • 456 citations

Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei

2000 • 433 citations

Perturbation of Nuclear Architecture by Long-Distance Chromosome Interactions

1996 • 425 citations

Dynamic Repositioning of Genes in the Nucleus of Lymphocytes Preparing for Cell Division

1999 • 393 citations

Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates

2002 • 389 citations

Non-random radial higher-order chromatin arrangements in nuclei of diploid human cells.

2001 • 368 citations

Functional architecture in the cell nucleus

2001 • 368 citations

Chromatin Boundaries in Budding Yeast

2002 • 352 citations

Mutation of yeast Ku genes disrupts the subnuclear organization of telomeres

1998 • 345 citations

Recurrent chromosome aberrations in cancer

2000 • 337 citations

Structure and dynamics of human interphase chromosome territories in vivo

1998 • 333 citations

Nuclear pore complexes in the organization of silent telomeric chromatin

2000 • 310 citations

A random-walk/giant-loop model for interphase chromosomes.

1995 • 306 citations

Nuclear Organization of Mammalian Genomes

1999 • 299 citations

A chromatin binding site in the tail domain of nuclear lamins that interacts with core histones.

1995 • 292 citations

Nuclear compartmentalization and gene activity

2000 • 292 citations

Arrangement of chromatin in the nucleus

1980 • 283 citations

Individual interphase chromosome domains revealed by in situ hybridization

1985 • 274 citations

Rabl's model of the interphase chromosome arrangement tested in Chinise hamster cells by premature chromosome condensation and laser-UV-microbeam experiments

1982 • 271 citations

Evidence for silencing compartments within the yeast nucleus: a role for telomere proximity and Sir protein concentration in silencer-mediated repression.

1996 • 270 citations

Re-modelling of nuclear architecture in quiescent and senescent human fibroblasts

2000 • 270 citations

Spatial organization of chromosomes in the salivary gland nuclei of Drosophila melanogaster.

1986 • 270 citations

Active and inactive genes localize preferentially in the periphery of chromosome territories.

1996 • 265 citations

Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus

2001 • 259 citations

Spatial Relationship between Transcription Sites and Chromosome Territories

1999 • 250 citations

Spatial Organization of Large-Scale Chromatin Domains in the Nucleus: A Magnified View of Single Chromosome Territories

1997 • 246 citations

Centromere clustering is a major determinant of yeast interphase nuclear organization

2000 • 245 citations

A Functional Enhancer Suppresses Silencing of a Transgene and Prevents Its Localization Close to Centromeric Heterochromatin

1999 • 244 citations

Binding of matrix attachment regions to lamin polymers involves single-stranded regions and the minor groove.

1994 • 240 citations

Specific staining of human chromosomes in Chinese hamster x man hybrid cell lines demonstrates interphase chromosome territories

1985 • 231 citations

Size-Dependent Positioning of Human Chromosomes in Interphase Nuclei

2000 • 226 citations

Spatial organization of active and inactive genes and noncoding DNA within chromosome territories

2002 • 224 citations

Compartmentalization of Interphase Chromosomes Observed in Simulation and Experiment

1999 • 207 citations

The Nuclear Topography of ABL, BCR, PML, and RAR Genes: Evidence for Gene Proximity in Specific Phases of the Cell Cycle and Stages of Hematopoietic Differentiation

1999 • 204 citations

Subchromosomal Positioning of the Epidermal Differentiation Complex (EDC) in Keratinocyte and Lymphoblast Interphase Nuclei

2002 • 204 citations

Arrangements of macro- and microchromosomes in chicken cells.

2001 • 201 citations

Direct Imaging of DNA in Living Cells Reveals the Dynamics of Chromosome Formation

1999 • 198 citations

Nuclear architecture and spatial positioning help establish transcriptional states of telomeres in yeast

2002 • 197 citations

Chromatin Dynamics in Interphase Nuclei and Its Implications for Nuclear Structure

1997 • 193 citations

Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator

2001 • 182 citations

Movement of the X Chromosome in Epilepsy

1988 • 169 citations

Precise Spatial Positioning of Chromosomes During Prometaphase: Evidence for Chromosomal Order

1995 • 165 citations

Silenced Chromatin Is Permissive to Activator Binding and PIC Recruitment

2001 • 159 citations

Review: Proximity effects in the production of chromosome aberrations by ionizing radiation

1997 • 156 citations

Transcription Sites Are Not Correlated with Chromosome Territories in Wheat Nuclei

1998 • 148 citations

In vivo binding of active heat shock transcription factor 1 to human chromosome 9 heterochromatin during stress

2002 • 147 citations

Human Genome and Diseases:¶Double-strand breaks and translocations in cancer

2002 • 144 citations

Large-scale Chromosomal Movements During Interphase Progression in Drosophila

1998 • 142 citations

Organization of Early and Late Replicating DNA in Human Chromosome Territories

1999 • 141 citations

Yeast heterochromatin is a dynamic structure that requires silencers continuously

2000 • 136 citations

PML bodies associate specifically with the MHC gene cluster in interphase nuclei

2001 • 132 citations

Regional and temporal specialization in the nucleus: a transcriptionally-active nuclear domain rich in PTF, Oct1 and PIKA antigens associates with specific chromosomes early in the cell cycle

1998 • 131 citations

High resolution analysis of interphase chromosome domains

2000 • 129 citations

Large-scale chromatin structure and function

1999 • 129 citations

The tail domain of lamin Dm₀binds histones H2A and H2B

1999 • 128 citations

Transcription Factor Dosage Affects Changes in Higher Order Chromatin Structure Associated with Activation of a Heterochromatic Gene

2000 • 124 citations

Association of snRNA genes with coiled bodies is mediated by nascent snRNA transcripts

1999 • 119 citations

Localisation and distance between ABL and BCR genes in interphase nuclei of bone marrow cells of control donors and patients with chronic myeloid leukaemia

1997 • 105 citations

Chromosomes exhibit preferential positioning in nuclei of quiescent human cells

1999 • 102 citations

Human Chromosomes 9, 12, and 15 Contain the Nucleation Sites of Stress-Induced Nuclear Bodies

2002 • 86 citations

Chromosomes as well as chromosomal subdomains constitute distinct units in interphase nuclei

1999 • 82 citations

Transcribed genes are localized according to chromosomal position within polarized Drosophila embryonic nuclei

1999 • 81 citations

Nuclear Topology of Murine, Cerebellar Purkinje Neurons: Changes as a Function of Development

2000 • 72 citations

Centromeres Reposition to the Nuclear Periphery during L6E9 Myogenesisin Vitro

1996 • 59 citations

Nuclear Domains Enriched in RNA 3′-processing Factors Associate with Coiled Bodies and Histone Genes in a Cell Cycle–dependent Manner

1999 • 56 citations

Evidence for a Relatively Random Array of Human Chromosomes on the Mitotic Ring

1999 • 55 citations

The relationship of radiation-induced dicentric yield to chromosome arm number

1973 • 49 citations

Quantitative Imaging of Pre-mRNA Splicing Factors in Living Cells

2000 • 47 citations

NEW EMBO MEMBER'S REVIEW: The inner nuclear membrane: simple, or very complex?

2001 • 34 citations

Spatial repositioning of centromeric domains during regrowth of axons in nuclei of murine dorsal root ganglion neuronsin vitro

1996 • 12 citations