Review: Proximity effects in the production of chromosome aberrations by ionizing radiation

The theory of polymer dynamics

1986 • 9,114 citations

International Journal of Radiation Biology

1959 • 1,730 citations

Chromosomal translocations in human cancer

1994 • 1,551 citations

Actions of Radiations on Living Cells

1955 • 1,242 citations

Delineation of individual human chromosomes in metaphase and interphase cells by in situ suppression hybridization using recombinant DNA libraries

1988 • 1,171 citations

Initial Events in the Cellular Effects of Ionizing Radiations: Clustered Damage in DNA

1994 • 1,142 citations

Role of Chromosome Territories in the Functional Compartmentalization of the Cell Nucleus

1993 • 504 citations

Rapid Translocation Frequency Analysis in Humans Decades after Exposure to Ionizing Radiation

1992 • 435 citations

AN ANALYSIS OF X-RAY INDUCED CHROMOSOMAL ABERRATIONS IN TRADESCANTIA

1940 • 411 citations

A Generalized Formulation of Dual Radiation Action¹

2012 • 378 citations

A Generalized Formulation of Dual Radiation Action

1978 • 367 citations

Current status of cytogenetic procedures to detect and quantify previous exposures to radiation

1988 • 360 citations

A Quantitative Comparison of Potentially Lethal Damage Repair and the Rejoining of Interphase Chromosome Breaks in Low Passage Normal Human Fibroblasts

1987 • 329 citations

A random-walk/giant-loop model for interphase chromosomes.

1995 • 306 citations

Effects of Radiations of Different Qualities on Cells: Molecular Mechanisms of Damage and Repair

1993 • 286 citations

Evidence for the organization of chromatin in megabase pair-sized loops arranged along a random walk path in the human G0/G1 interphase nucleus.

1995 • 284 citations

Constraints on Energy Deposition and Target Size of Multiply Damaged Sites Associated with DNA Double-strand Breaks

1992 • 271 citations

The Molecular Theory of Radiation Biology

1981 • 248 citations

Fish “painting” patterns resulting from complex exchanges

1994 • 190 citations

Chromosome end associations, telomeres and telomerase activity in ataxia telangiectasia cells

1995 • 167 citations

SITES OF RADIATION INDUCED CHROMOSOME EXCHANGES.

1970 • 139 citations

Fluorescencein SituHybridization Detection of Chromosomal Aberrations in Human Lymphocytes: Applicability to Biological Dosimetry

1995 • 118 citations

Frequencies of Complex Chromosome Exchange Aberrations Induced by²³⁸Pu α-particles and Detected by Fluorescencein SituHybridization Using Single Chromosome-specific Probes

1995 • 118 citations

The Breakage-and-Reunion Theory and the Exchange Theory for Chromosomal Aberrations Induced by Ionizing Radiations: A Short History

1974 • 111 citations

Quantification of low-level radiation exposure by conventional chromosome aberration analysis

1995 • 108 citations

Fundamentals of microdosimetry

1985 • 106 citations

The Relationship of DNA and Chromosome Damage to Survival of Synchronized X-Irradiated L5178Y Cells: II. Repair

1988 • 103 citations

Ionizing Radiation Damage and Its Early Development in Chromosomes

1993 • 101 citations

Chromosomal "Fingerprints" of Prior Exposure to Densely Ionizing Radiation

1994 • 95 citations

Chromosome-exchange Aberrations in Human Lymphocytes

1967 • 92 citations

Dose-response curves for simple and complex chromosome aberrations induced by X-rays and detected using fluorescence in situ hybridization

1996 • 88 citations

Radiation-Induced Damage, Repair and Exchange Formation in Different Chromosomes of Human Fibroblasts Determined by Fluorescence In Situ Hybridization

1994 • 87 citations

Using three-color chromosome painting to test chromosome aberration models.

1993 • 84 citations

Analysis for DNA-proportional Distribution of Radiation-induced Chromosome Aberrations in Various Triple Combinations of Human Chromosomes Using Fluorescencein SituHybridization

1994 • 82 citations

Chromosome analysis by fluorescence in situ hybridization: further indications for a non-DNA-proportional involvement of single chromosomes in radiation-induced structural aberrations

1996 • 82 citations

Track Structure, Lesion Development, and Cell Survival

1990 • 79 citations

The Induction of Chromosome Exchange Aberrations by Carbon Ultrasoft X-rays in V79 Hamster Cells

1985 • 78 citations

Frequency and distribution studies of asymmetrical versus symmetrical chromosome aberrations

1982 • 78 citations

Relationship of Microdosimetric Techniques to Applications in Biological Systems

1987 • 77 citations

Radiation-induced chromosomal breakage and rejoining in interphase-metaphase chromosomes of human lymphocytes

1991 • 75 citations

Statistical Interpretation of the Overdispersed Distribution of Radiation-Induced Dicentric Chromosome Aberrations at High LET

1981 • 73 citations

Recent Developments in the Assessment of Chromosomal Damage

1994 • 67 citations

Radiation-induced chromosomal aberrations in the plant Tradescantia: Dose-response curves I. Preliminary considerations

1975 • 64 citations

The Interphase Nucleus as a Dynamic Structure

1994 • 60 citations

Fluorescence In Situ Hybridization in Cancer and Radiation Biology

1994 • 59 citations

Validation of Chromosome Painting. II. A Detailed Analysis of Aberrations Following High Doses of Ionizing Radiationin Vitro

1995 • 59 citations

Chromatid Aberrations inTradescantiaPollen Tubes Induced by Monochromatic X-rays of Quantum Energy 3 and 1·5 keV

1964 • 58 citations

Chromosomal Damage and Repair in G 1 -Phase Chinese Hamster Ovary Cells Exposed to Charged-Particle Beams

1994 • 56 citations

Comparison of γ-ray induced dicentric yields in human lymphocytes measured by conventional analysis and FISH

1995 • 54 citations

Visualization of Nonreciprocal Chromosome Exchanges in Irradiated Human Fibroblasts by Fluorescence In Situ Hybridization

1993 • 51 citations

The Ratio of Dicentrics to Centric Rings Produced in Human Lymphocytes by Acute Low-LET Radiation

1992 • 51 citations

DNA damage caused by ionizing radiation

1992 • 51 citations

Use of a Three-Color Chromosome In Situ Suppression Technique for the Detection of Past Radiation Exposure

1996 • 51 citations

Biophysical Studies with Spatially Correlated Ions: 4. Analysis of Cell Survival Data for Diatomic Deuterium

1980 • 50 citations

The relationship of radiation-induced dicentric yield to chromosome arm number

1973 • 49 citations

Testing the Notion of the One-Hit Exchange

1990 • 48 citations

X-ray Biological Dosimetry Performed by Selective Painting of Human Chromosomes 1 and 2

1995 • 46 citations

Induction and Repair of Chromosome Aberrations in scid Cells Measured by Premature Chromosome Condensation

1996 • 45 citations

Inactivation of Synchronized Mammalian Cells with Low-Energy X Rays: Results and Significance

1987 • 44 citations

Kinetics of the Formation of Chromosome Aberrations in X-Irradiated Human Lymphocytes: Analysis by Premature Chromosome Condensation with Delayed Fusion

1995 • 44 citations

Mechanism of chromosome exchange formation in human fibroblasts: Insights from “chromosome painting”

1993 • 41 citations

Biological Dosimetry by Interphase Chromosome Painting

1996 • 41 citations

PAINT: a proposed nomenclature for structural aberrations detected by whole chromosome painting

1995 • 41 citations

Ratios of radiation-produced chromosome aberrations as indicators of large-scale DNA geometry during interphase.

1993 • 40 citations

Comparison of the yields of translocations and dicentrics measured using conventional Giemsa staining and chromosome painting

1996 • 40 citations

Comparison of gamma-ray-induced chromosome ring and inversion frequencies.

1995 • 38 citations

Theoretical predictions on the equality of radiation-produced dicentrics and translocations detected by chromosome painting

1996 • 37 citations

Fluorescence in situ hybridization using digital imaging microscopy.

1993 • 36 citations

Modification of the Theory of Dual Radiation Action for Attenuated Fields: II. Application to the Analysis of Soft X-Ray Results

1984 • 34 citations

G-Banding analysis of radiation-induced chromosome damage in lymphocytes of hiroshima A-bomb survivors

1992 • 32 citations

Use of Fluorescencein SituHybridization to Determine the Relationship between Chromosome Aberrations and Cell Survival in Eight Human Fibroblast Strains

1995 • 31 citations

On the mechanism of the formation of chromosomal aberrations by ionising radiation

1996 • 31 citations

Chromosomal damage induced in human lymphocytes by low doses of D-T neutrons

1986 • 31 citations

Chromosome Aberrations Produced by Radiation: The Relationship between Excess Acentric Fragments and Dicentrics

1995 • 30 citations

Effect of LET on Chromosomal Aberration Yields. I. Do Long-lived, Exchange-prone Double Strand Breaks Play a Role?

1993 • 29 citations

Charged Particle Cytogenetics: Effects of LET, Fluence, and Particle Separation on Chromosome Aberrations

1985 • 28 citations

On the probability of interaction between elementary radiation-induced chromosomal injuries

1988 • 27 citations

Direct Biological Evidence for a Significant Neutron Dose to Survivors of the Hiroshima Atomic Bomb

1996 • 25 citations

Initial Damage in Human Interphase Chromosomes from Alpha Particles with Linear Energy Transfers Relevant to Radon Exposure

1994 • 25 citations

The Application of Track Calculations to Radiobiology: III. Analysis of the Molecular Beam Experiment Results

1984 • 24 citations

The over-dispersion between cells of chromosomal aberrations

1979 • 23 citations

Modelling the kinetics of chromosome exchange formation in human cells exposed to ionising radiation

1996 • 21 citations

Evolution of DNA damage in irradiated cells

1992 • 21 citations

The Induction of Chromosome Exchange Aberrations by Ionizing Radiations: The ‘Site Concept’

1965 • 21 citations

Ratios of Radiation-Produced Chromosome Aberrations as Indicators of Large-Scale DNA Geometry during Interphase

1993 • 20 citations

Chromosome aberration analysis in atomic bomb survivors and Thorotrast patients using two- and three-colour chromosome painting of chromosomal subsets

1996 • 19 citations

Simulation of the distribution of chromosome targets in cell nuclei under topological constraints

1995 • 19 citations

Dual Radiation Action and the Initial Slope of Survival Curves

1985 • 17 citations

Rejoining and Misrejoining of Radiation-Induced Chromatin Breaks. II. Biophysical Model

1996 • 16 citations

Comparative study of the repair kinetics of chromosomal aberrations and DNA strand breaks in proliferating and quiescent

1996 • 16 citations

The Induction of Chromosome Aberrations in Human Lymphocytes by 24 keV Neutrons

1990 • 16 citations

Noninvolvement of the X Chromosome in Radiation-Induced Chromosome Translocations in the Human Lymphoblastoid Cell Line TK6

1994 • 9 citations

Response to "Comments on 'Direct Biological Evidence for a Significant Neutron Dose to Survivors of the Hiroshima Atomic Bomb'" by E. Schmid and M. Bauchinger

1996 • 9 citations

Track Structure, Chromosome Geometry and Chromosome Aberrations

1994 • 8 citations

A random walk model for interphase chromosomes and the relationship between centric rings, acentric rings and excess acentric fragments produced by low-LET radiation.

1997 • 5 citations

Generalised Microdosimetric Calculations of Cell-to-Cell Variance

1994 • 3 citations

Deleted Work

1955 • 0 citations