Chromatin Motion Is Constrained by Association with Nuclear Compartments in Human Cells

Genomic sequencing.

1984 • 8,343 citations

Random walks in biology

1983 • 2,394 citations

Chromosome territories, nuclear architecture and gene regulation in mammalian cells

2001 • 2,239 citations

High mobility of proteins in the mammalian cell nucleus

2000 • 1,163 citations

Differences in the Localization and Morphology of Chromosomes in the Human Nucleus

1999 • 902 citations

In vivo localization of DNA sequences and visualization of large-scale chromatin organization using lac operator/repressor recognition.

1996 • 709 citations

Characterization of a newly derived human sarcoma cell line (HT-1080)

1974 • 681 citations

The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells

2001 • 673 citations

Interphase chromosomes undergo constrained diffusional motion in living cells

1997 • 656 citations

New pUC-derived cloning vectors with different selectable markers and DNA replication origins

1991 • 497 citations

Perinuclear localization of chromatin facilitates transcriptional silencing

1998 • 466 citations

Chromosome Dynamics in the Yeast Interphase Nucleus

2001 • 456 citations

Nuclear pore complexes in the organization of silent telomeric chromatin

2000 • 310 citations

Genetic modification of heterochromatic association and nuclear organization in Drosophila

1996 • 306 citations

Visualization of gene activity in living cells

2000 • 305 citations

Multiple regimes of constrained chromosome motion are regulated in the interphase Drosophila nucleus

2001 • 259 citations

A monoclonal antibody recognizing nuclear matrix-associated nuclear bodies

1992 • 258 citations

Chromatin Dynamics in Interphase Nuclei and Its Implications for Nuclear Structure

1997 • 193 citations

The Positioning and Dynamics of Origins of Replication in the Budding Yeast Nucleus

2001 • 186 citations

Interphase movements of a DNA chromosome region modulated by VP16 transcriptional activator

2001 • 182 citations

Genes and genomes: Chromosome bands – flavours to savour

1993 • 182 citations

Interphase Cell Cycle Dynamics of a Late-Replicating, Heterochromatic Homogeneously Staining Region: Precise Choreography of Condensation/Decondensation and Nuclear Positioning

1998 • 180 citations

Visualizing chromosome dynamics with GFP

2001 • 165 citations

Inhibition of RNA Polymerase II Transcription Causes Chromatin Decondensation, Loss of Nucleolar Structure, and Dispersion of Chromosomal Domains

1996 • 150 citations

Cell nucleus: Chromosome dynamics in nuclei of living cells

1998 • 96 citations

Targeted breakage of a human chromosome mediated by cloned human telomeric DNA

1992 • 80 citations

Mapping of Replication Initiation Sites in Human Ribosomal DNA by Nascent-Strand Abundance Analysis

1995 • 67 citations

Putting the genome on the map

1998 • 61 citations

Chromosomal constitution of nucleolus-associated chromatin in man

1976 • 47 citations