Nuclear Domains Enriched in RNA 3′-processing Factors Associate with Coiled Bodies and Histone Genes in a Cell Cycle–dependent Manner

Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I

1977 • 12,015 citations

Rapid flow cytofluorometric analysis of mammalian cell cycle by propidium iodide staining.

1975 • 1,734 citations

Enzymatic synthesis of biotin-labeled polynucleotides: novel nucleic acid affinity probes.

1981 • 1,165 citations

Structure and Function in the Nucleus

1998 • 925 citations

A novel nuclear structure containing the survival of motor neurons protein.

1996 • 759 citations

Dynamics of three-dimensional replication patterns during the s-phase, analysed by double labelling of dna and confocal microscopy

1992 • 721 citations

Fine structural organization of the interphase nucleus in some mammalian cells

1969 • 632 citations

Nopp 140 shuttles on tracks between nucleolus and cytoplasm

1992 • 409 citations

Transcription-dependent colocalization of the U1, U2, U4/U6, and U5 snRNPs in coiled bodies

1992 • 402 citations

Human autoantibody to a novel protein of the nuclear coiled body: immunological characterization and cDNA cloning of p80-coilin.

1991 • 369 citations

Immunological and ultrastructural studies of the nuclear coiled body with autoimmune antibodies

1991 • 327 citations

The protein that binds the 3' end of histone mRNA: a novel RNA-binding protein required for histone pre-mRNA processing.

1996 • 260 citations

Nonrandom gene organization: structural arrangements of specific pre-mRNA transcription and splicing with SC-35 domains.

1995 • 251 citations

Coiled bodies contain U7 small nuclear RNA and associate with specific DNA sequences in interphase human cells.

1995 • 244 citations

A multisubunit factor, CstF, is required for polyadenylation of mammalian pre-mRNAs.

1990 • 243 citations

The cellular organization of gene expression

1998 • 243 citations

Localisation of rapidly and slowly labelled nuclear RNA as visualized by high resolution autoradiography

1971 • 233 citations

Nuclear distribution of transcription factors in relation to sites of transcription and RNA polymerase II

1997 • 217 citations

Assembly of snRNP-containing coiled bodies is regulated in interphase and mitosis--evidence that the coiled body is a kinetic nuclear structure.

1993 • 214 citations

Immunocytochemical analysis of the coiled body in the cell cycle and during cell proliferation.

1993 • 201 citations

Restoration of confocal images for quantitative image analysis

1995 • 190 citations

The coiled body

1993 • 181 citations

Association between the nucleolus and the coiled body

1990 • 175 citations

Nucleologenesis: U3 snRNA-containing prenucleolar bodies move to sites of active pre-rRNA transcription after mitosis.

1994 • 162 citations

Histone genes are located at the sphere loci of newt lampbrush chromosomes

1981 • 160 citations

Is the sphere organelle/coiled body a universal nuclear component?

1995 • 150 citations

The regulation of histone gene expression during the cell cycle

1991 • 149 citations

Mutational analysis of p80 coilin indicates a functional interaction between coiled bodies and the nucleolus.

1995 • 146 citations

Differential interaction of splicing snRNPs with coiled bodies and interchromatin granules during mitosis and assembly of daughter cell nuclei.

1994 • 135 citations

U2 and U1 snRNA gene loci associate with coiled bodies

1995 • 105 citations

The RNA 3′ cleavage factors CstF 64 kDa and CPSF 100 kDa are concentrated in nuclear domains closely associated with coiled bodies and newly synthesized RNA.

1996 • 103 citations

U7 small nuclear RNA in C snurposomes of the Xenopus germinal vesicle.

1993 • 98 citations

Heat-labile regulatory factor is required for 3' processing of histone precursor mRNAs.

1987 • 90 citations

Human genes encoding U3 snRNA associate with coiled bodies in interphase cells and are clustered on chromosome 17p11.2 in a complex inverted repeat structure

1997 • 89 citations

The Mechanism of 3′ Cleavage and Polyadenylation of Eukaryotic Pre-mRNA1

1997 • 88 citations

Coiled Bodies and U2 snRNA Genes Adjacent to Coiled Bodies Are Enriched in Factors Required for snRNA Transcription

1998 • 86 citations

Human histone genes map to multiple chromosomes.

1986 • 83 citations

Synchronization of human diploid fibroblasts at multiple stages of the cell cycle*1

1988 • 76 citations

Comparison of synchronized Chinese hamster ovary cells obtained by mitotic shake‐off, hydroxyurea, aphidicolin, or methotrexate

1987 • 72 citations

Structural organization of the nucleolus in mammalian cells.

1986 • 67 citations

All Known Human H1 Histone Genes Except the H10 Gene Are Clustered on Chromosome 6

1993 • 65 citations

The cdk7-cyclin H-MAT1 complex associated with TFIIH is localized in coiled bodies.

1997 • 64 citations

Histone genes are located at the sphere loci of Xenopus lampbrush chromosomes

1991 • 64 citations

Nuclear neighbours: The spatial and functional organization of genes and nuclear domains

1998 • 62 citations

Biochemical demonstration of complex formation of histone pre-mRNA with U7 small nuclear ribonucleoprotein and hairpin binding factors.

1992 • 59 citations

Nuclear Domains Involved in RNA Synthesis, RNA Processing, and Replication

1996 • 57 citations

The Stem-Loop Binding Protein (SLBP1) Is Present in Coiled Bodies of the Xenopus Germinal Vesicle

1999 • 56 citations

Histone gene transcription: A model for responsiveness to an integrated series of regulatory signals mediating cell cycle control and proliferation/differentiation interrelationships

1994 • 50 citations

Association of the neuron-specific RNA binding domain-containing protein ELAV with the coiled body inDrosophila neurons

1997 • 41 citations

ScilImage: A Multi-layered Environment for Use and Development of Image Processing Software

1994 • 36 citations

Cell Synchrony Techniques. I. A Comparison of Methods

1984 • 35 citations

Association of RNA with the B and C snurposomes of Xenopus oocyte nuclei

1991 • 28 citations

Cell Synchrony Techniques

1987 • 27 citations

Nucleic acid compartmentalization within the cell nucleus by in situ transferase‐immunogold techniques

1995 • 26 citations

Cytochemical and immunocytochemical study of coiled bodies in different cultured cell lines

1994 • 22 citations

Standardized shake-off to synchronize cultured CHO cells

1983 • 20 citations