Involvement of BCL-2 in glucocorticoid-induced apoptosis of human pre-B-leukemias.

The Steroid and Thyroid Hormone Receptor Superfamily

1988 • 7,590 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death

1990 • 3,817 citations

Gene regulation by steroid hormones

1989 • 3,466 citations

Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells

1988 • 3,194 citations

STEROID RECEPTOR REGULATED TRANSCRIPTION OF SPECIFIC GENES AND GENE NETWORKS

1985 • 1,911 citations

Involvement of the bcl -2 Gene in Human Follicular Lymphoma

1985 • 1,797 citations

Cloning of the Chromosome Breakpoint of Neoplastic B Cells with the t(14;18) Chromosome Translocation

1984 • 1,761 citations

Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis

1989 • 1,739 citations

Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages.

1989 • 1,540 citations

Glucocorticoid activation of a calcium-dependent endonuclease in thymocyte nuclei leads to cell death.

1984 • 1,441 citations

Antibodies to CD3/T-cell receptor complex induce death by apoptosis in immature T cells in thymic cultures

1989 • 1,159 citations

The molecular control of cell division, differentiation commitment and maturation in haemopoietic cells

1989 • 1,097 citations

The t(14;18) Chromosome Translocations Involved in B-Cell Neoplasms Result from Mistakes in VDJ Joining

1985 • 1,021 citations

Nucleotide sequence of a t(14;18) chromosomal breakpoint in follicular lymphoma and demonstration of a breakpoint-cluster region near a transcriptionally active locus on chromosome 18.

1985 • 972 citations

Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.

1990 • 926 citations

Activation of programmed cell death (apoptosis) by cisplatin, other anticancer drugs, toxins and hyperthermia

1990 • 887 citations

Steroid Receptor Family: Structure and Functions

1990 • 820 citations

Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis.

1983 • 616 citations

Cyclosporin A inhibits activation-induced cell death in T-cell hybridomas and thymocytes

1989 • 513 citations

Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.

1990 • 485 citations

IL-2 addiction: withdrawal of growth factor activates a suicide program in dependent T cells.

1986 • 380 citations

Death of mature T cells by separate ligation of CD4 and the T-cell receptor for antigen

1990 • 375 citations

Phagocytosis of aged human neutrophils by macrophages is mediated by a novel "charge-sensitive" recognition mechanism.

1989 • 298 citations

Radiation-induced Interphase Death of Rat Thymocytes is Internally Programmed (Apoptosis)

1988 • 239 citations

A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia.

1984 • 227 citations

Regulation of apoptosis in interleukin-3-dependent hemopoietic cells by interleukin-3 and calcium ionophores.

1990 • 226 citations

Programmed death of autoreactive thymocytes

1990 • 224 citations

Activation of polyubiquitin gene expression during developmentally programmed cell death

1990 • 214 citations

Postmetamorphic cell death in the nervous and muscular systems of Drosophila melanogaster

1990 • 193 citations

DNA fragmentation induced in macrophages by gliotoxin does not require protein synthesis and is preceded by raised inositol triphosphate levels.

1990 • 185 citations

BCL2-mediated tumorigenicity of a human T-lymphoid cell line: synergy with MYC and inhibition by BCL2 antisense.

1990 • 157 citations

Cell death in embryogenesis

1981 • 138 citations

Activation of internucleosomal DNA cleavage in human CEM lymphocytes by glucocorticoid and novobiocin. Evidence for a non-Ca2(+)-requiring mechanism(s).

1990 • 134 citations

Interleukin 3-specific tyrosine phosphorylation of a membrane glycoprotein of Mr 150,000 in multi-factor-dependent myeloid cell lines.

1987 • 129 citations

Stimulation of factor-dependent myeloid cell lines with interleukin 3 induces tyrosine phosphorylation of several cellular substrates.

1988 • 117 citations

Spontaneous Regression in Basal Cell Carcinomas

1979 • 112 citations

Glucocorticoid Effect on Oncogene/Growth Gene Expression in Human T Lymphoblastic Leukemic Cell Line CCRF-CEM

1989 • 101 citations

Glucocorticoid-induced Lymphocytolysis Is Not Mediated by an Induced Endonuclease

1989 • 94 citations

Programmed Cell Death: New Thoughts and Relevance to Aging

1990 • 90 citations

Control of red cell production: the roles of programmed cell death (apoptosis) and erythropoietin

1990 • 78 citations

Role of myc in the abrogation of IL3 dependence of myeloid FDC-P1 cells.

1987 • 75 citations

NK cell‐induced cytotoxicity is dependent on a Ca²⁺ increase in the target

1990 • 73 citations

Second Cytotoxic Pathway of Diphtheria Toxin Suggested by Nuclease Activity

1989 • 66 citations

The bcl-2 gene encodes a novel G protein

1989 • 61 citations

UV Light and Ionizing Radiations Cause Programmed Death of Rat Chloroleukaemia Cells by Inducing Retropositions of a Mobile DNA Element (L1Rn)

1990 • 54 citations

Hormonal control of muscle atrophy and degeneration in the moth Antheraea polyphemus

1984 • 53 citations

Regression of nitrosamine-induced pancreatic cancers in hamsters treated with luteinizing hormone-releasing hormone antagonists or agonists.

1990 • 49 citations

Mapping the human glucocorticoid receptor for leukemic cell death

1991 • 48 citations

The glucocorticoid receptor and its endogenous regulators.

1990 • 31 citations

<scp>DNA</scp>‐Dependent <scp>DNA</scp> Polymerases

1997 • 21 citations

Autonomous death of amphibian (Xenopus laevis) cranial myotomes

1989 • 20 citations

Natural Killer Cells and Cytotoxic T Cells Induce DNA Fragmentation in Both Human and Murine Target Cells in Vitro

1989 • 14 citations