Cholesterol Depletion Suppresses the Translational Diffusion of Class II Major Histocompatibility Complex Proteins in the Plasma Membrane

Lipid rafts and signal transduction

2000 • 6,079 citations

Regulation of Renal Organic Anion Transporter 3 (SLC22A8) Expression and Function by the Integrity of Lipid Raft Domains and their Associated Cytoskeleton

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FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES

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Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

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Structure and Function of Sphingolipid- and Cholesterol-rich Membrane Rafts

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THE CAVEOLAE MEMBRANE SYSTEM

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Brownian motion in biological membranes.

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Lipid Domain Structure of the Plasma Membrane Revealed by Patching of Membrane Components

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A Role for Lipid Shells in Targeting Proteins to Caveolae, Rafts, and Other Lipid Domains

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Single particle tracking. Analysis of diffusion and flow in two-dimensional systems

1991 • 1,120 citations

Sphingolipid–Cholesterol Rafts Diffuse as Small Entities in the Plasma Membrane of Mammalian Cells

2000 • 987 citations

Drug-Induced Changes of Cytoskeletal Structure and Mechanics in Fibroblasts: An Atomic Force Microscopy Study

2000 • 925 citations

Membrane Compartmentation Is Required for Efficient T Cell Activation

1998 • 925 citations

Phospholipids undergo hop diffusion in compartmentalized cell membrane

2002 • 878 citations

Cellular Cholesterol Efflux Mediated by Cyclodextrins

1995 • 864 citations

Methods of single-molecule fluorescence spectroscopy and microscopy

2003 • 837 citations

Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain

1997 • 644 citations

Anomalous diffusion due to obstacles: a Monte Carlo study

1994 • 611 citations

Single-particle tracking: the distribution of diffusion coefficients

1997 • 574 citations

Properties of lipid microdomains in a muscle cell membrane visualized by single molecule microscopy

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Lateral diffusion in the liquid phases of dimyristoylphosphatidylcholine/cholesterol lipid bilayers: a free volume analysis

1992 • 563 citations

Membrane cholesterol, lateral mobility, and the phosphatidylinositol 4,5-bisphosphate-dependent organization of cell actin

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Constrained diffusion or immobile fraction on cell surfaces: a new interpretation

1996 • 469 citations

Effects of cytochalasin D and latrunculin B on mechanical properties of cells

2001 • 451 citations

Dynamics of putative raft-associated proteins at the cell surface

2004 • 446 citations

Condensed complexes of cholesterol and phospholipids

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Ultrafine Membrane Compartments for Molecular Diffusion as Revealed by Single Molecule Techniques

2004 • 429 citations

Lipid-dependent Targeting of G Proteins into Rafts

2000 • 428 citations

High-Resolution FRET Microscopy of Cholera Toxin B-Subunit and GPI-anchored Proteins in Cell Plasma Membranes

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Relationship of Lipid Rafts to Transient Confinement Zones Detected by Single Particle Tracking

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Single-molecule imaging analysis of Ras activation in living cells

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Intracellular Trafficking of Cholesterol Monitored with a Cyclodextrin

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The translational and rotational drag on a cylinder moving in a membrane

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Compartmentalized Activation of the High Affinity Immunoglobulin E Receptor within Membrane Domains

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Critical Role for Cholesterol in Lyn-mediated Tyrosine Phosphorylation of FcεRI and Their Association with Detergent-resistant Membranes

1999 • 327 citations

Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation

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Cholesterol depletion induces large scale domain segregation in living cell membranes

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Lateral diffusion in an archipelago. Single-particle diffusion

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Lateral Diffusion in an Archipelago

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Liquid-Liquid Immiscibility in Membranes

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Probing Red Cell Membrane Cholesterol Movement with Cyclodextrin

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Translational Diffusion of Individual Class II MHC Membrane Proteinsin Cells

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Condensed Complexes of Cholesterol and Phospholipids

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Cholesterol in Membrane Models

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Lateral mobility in membranes as detected by fluorescence recovery after photobleaching

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Single-particle tracking: effects of corrals

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Dynamics of raft molecules in the cell and artificial membranes: approaches by pulse EPR spin labeling and single molecule optical microscopy

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CD40 signaling in human dendritic cells is initiated within membrane rafts

2000 • 183 citations

Disposition of intracellular cholesterol in human fibroblasts.

1991 • 181 citations

Hypoxia impairs cell fusion and differentiation process in human cytotrophoblast, in vitro

1996 • 175 citations

Anomalous Diffusion of Major Histocompatibility Complex Class I Molecules on HeLa Cells Determined by Single Particle Tracking

1999 • 174 citations

How cholesterol homeostasis is regulated by plasma membrane cholesterol in excess of phospholipids

2004 • 171 citations

Chemical Activity of Cholesterol in Membranes

2000 • 166 citations

Selective Accumulation of Raft-Associated Membrane Protein Lat in T Cell Receptor Signaling Assemblies

2000 • 154 citations

Effects of membrane cholesterol on the sensitivity of the GABAA receptor to GABA in acutely dissociated rat hippocampal neurones

2001 • 154 citations

Association of GAP-43 with Detergent-resistant Membranes Requires Two Palmitoylated Cysteine Residues

1998 • 144 citations

Expression of a class II major histocompatibility complex (MHC) heterodimer in a lipid-linked form with enhanced peptide/soluble MHC complex formation at low pH.

1991 • 143 citations

MHC Class II-Peptide Complexes and APC Lipid Rafts Accumulate at the Immunological Synapse

2003 • 135 citations

Formation of a Highly Peptide-Receptive State of Class II MHC

1998 • 133 citations

Efflux of Cholesterol from Different Cellular Pools

2000 • 127 citations

Determination of plasma membrane lipid mass and composition in cultured Chinese hamster ovary cells using high gradient magnetic affinity chromatography

1993 • 126 citations

Intracellular Phosphotyrosine Induction by Major Histocompatibility Complex Class II Requires Co-aggregation with Membrane Rafts

1999 • 113 citations

Regulation of endothelial nitric oxide synthase by the actin cytoskeleton

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Differently anchored influenza hemagglutinin mutants display distinct interaction dynamics with mutual rafts

2003 • 107 citations

Potentiometric Measurement of Intracellular Redox Activity

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Acyl and alkyl chain length of GPI‐anchors is critical for raft association in vitro

1999 • 90 citations

Lateral diffusion in a mixture of mobile and immobile particles. A Monte Carlo study

1990 • 72 citations

Lateral diffusion and aggregation. A Monte Carlo study

1992 • 66 citations

Structure of the glycosylphosphatidylinositol membrane anchor of human placental alkaline phosphatase

1994 • 64 citations

Hypoxia Inactivates Inducible Nitric Oxide Synthase in Mouse Macrophages by Disrupting Its Interaction with α-Actinin 4

2003 • 64 citations

Lateral diffusion of M-13 coat protein in mixtures of phosphatidylcholine and cholesterol

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Nocodazole Inhibits Signal Transduction by the T Cell Antigen Receptor

1998 • 48 citations

Contribution of actin cytoskeletal alterations to ATP depletion and calcium-induced proximal tubule cell injury

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Electric field effect on cholesterol–phospholipid complexes

2000 • 34 citations

Peptide Binding to Active Class II MHC Protein on the Cell Surface

2001 • 17 citations