Concentration of MHC class II molecules in lipid rafts facilitates antigen presentation

Functional rafts in cell membranes

1997 • 9,471 citations

The Immunological Synapse: A Molecular Machine Controlling T Cell Activation

1999 • 3,025 citations

FUNCTIONS OF LIPID RAFTS IN BIOLOGICAL MEMBRANES

1998 • 2,942 citations

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

1992 • 2,905 citations

Three-dimensional segregation of supramolecular activation clusters in T cells

1998 • 2,316 citations

Caveolin, a protein component of caveolae membrane coats

1992 • 2,230 citations

GPI-anchored proteins are organized in submicron domains at the cell surface

1998 • 1,207 citations

Co-purification and Direct Interaction of Ras with Caveolin, an Integral Membrane Protein of Caveolae Microdomains

1996 • 1,006 citations

Sphingolipid–Cholesterol Rafts Diffuse as Small Entities in the Plasma Membrane of Mammalian Cells

2000 • 987 citations

T Lymphocyte Costimulation Mediated by Reorganization of Membrane Microdomains

1999 • 964 citations

Membrane Compartmentation Is Required for Efficient T Cell Activation

1998 • 925 citations

Cellular Cholesterol Efflux Mediated by Cyclodextrins

1995 • 864 citations

LAT Palmitoylation

1998 • 837 citations

Aggregation of Lipid Rafts Accompanies Signaling via the T Cell Antigen Receptor

1999 • 800 citations

Caveolae, DIGs, and the dynamics of sphingolipid—cholesterol microdomains

1997 • 783 citations

A detergent-free method for purifying caveolae membrane from tissue culture cells.

1995 • 732 citations

A Novel Adaptor Protein Orchestrates Receptor Patterning and Cytoskeletal Polarity in T-Cell Contacts

1998 • 708 citations

Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain

1997 • 644 citations

Engagement of T cell receptor triggers its recruitment to low-density detergent-insoluble membrane domains

1998 • 630 citations

Cholesterol Is Required for Surface Transport of Influenza Virus Hemagglutinin

1998 • 555 citations

Transport of Peptide-MHC Class II Complexes in Developing Dendritic Cells

2000 • 483 citations

A Role for Lipid Rafts in B Cell Antigen Receptor Signaling and Antigen Targeting

1999 • 473 citations

Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation

1990 • 468 citations

The Minimal Number of Class II MHC-Antigen Complexes Needed for T Cell Activation

1990 • 410 citations

MHC class II structure, occupancy and surface expression determined by post-endoplasmic reticulum antigen binding

1991 • 394 citations

S-acylation of LCK protein tyrosine kinase is essential for its signalling function in T lymphocytes

1997 • 364 citations

Compartmentalized Activation of the High Affinity Immunoglobulin E Receptor within Membrane Domains

1997 • 353 citations

Exclusion of CD45 inhibits activity of p56lck associated with glycolipid-enriched membrane domains.

1996 • 312 citations

Antigen presentation by supported planar membranes containing affinity-purified I-Ad.

1984 • 281 citations

Engagement of GPI-Linked CD48 Contributes to TCR Signals and Cytoskeletal Reorganization

1998 • 278 citations

GPI-microdomains: a role in signalling via immunoreceptors

1999 • 270 citations

T‐Cell Unresponsiveness in vivo and in vitro: Fine Specificity of Induction and Molecular Characterization of the Unresponsive State

1987 • 190 citations

Processed antigen binds to newly synthesized mhc class II molecules in antigen-specific B lymphocytes

1991 • 188 citations

Intracellular Phosphotyrosine Induction by Major Histocompatibility Complex Class II Requires Co-aggregation with Membrane Rafts

1999 • 113 citations

Functionally distinct subsites on a class II major histocompatibility complex molecule

1987 • 95 citations

HLA class I and II antigens are partially co-clustered in the plasma membrane of human lymphoblastoid cells

1997 • 87 citations

The biogenesis of the MHC class II compartment in human I-cell disease B lymphoblasts.

1996 • 72 citations

Phosphorylation Regulates the Delivery of MHC Class II Invariant Chain Complexes to Antigen Processing Compartments

1998 • 60 citations

A naturally processed peptide presented by HLA-A*0201 is expressed at low abundance and recognized by an alloreactive CD8+ cytotoxic T cell with apparent high affinity.

1997 • 49 citations

T cell activation by preformed, long-lived Ia-peptide complexes. Quantitative aspects.

1988 • 28 citations

Dynamics of molecules involved in antigen presentation: effects of fixation

1999 • 24 citations