Role of non-neuronal and neuronal acetylcholine in the airways

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1997 • 1,636 citations

Handbuch der Experimentellen Pharmakologie

1939 • 889 citations

Über humorale übertragbarkeit der Herznervenwirkung

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The Cytoskeleton and Cell Signaling: Component Localization and Mechanical Coupling

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Mucociliary clearance in the airways.

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The Peripheral Nervous System

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Neural control of human airways in health and disease.

1986 • 613 citations

ACETYLCHOLINE METABOLISM OF A SYMPATHETIC GANGLION

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Über humorale Übertragbarkeit der Herznervenwirkung

1924 • 473 citations

Non-neuronal acetylcholine, a locally acting molecule, widely distributed in biological systems: Expression and function in humans

1998 • 407 citations

Functional identification of a vesicular acetylcholine transporter and its expression from a “cholinergic” gene locus.

1994 • 383 citations

Synaptic Vesicles and Exocytosis

1994 • 371 citations

High affinity choline transport and acetylCoA production in brain and their roles in the regulation of acetylcholine synthesis

1979 • 360 citations

Synaptic vesicle biogenesis, docking, and fusion: a molecular description

1996 • 349 citations

THE FORMATION OF ACETYLCHOLINE. A NEW ENZYME: "CHOLINE ACETYLASE"

1943 • 326 citations

Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter. I. Central nervous system

1998 • 324 citations

Muscarinic inhibitory receptors in pulmonary parasympathetic nerves in the guinea‐pig

1984 • 318 citations

Regulation of Tracheobronchial Smooth Muscle

1963 • 302 citations

Cytological Distributions and Physiological Functions of Cholinesterases

1963 • 297 citations

Effects and distribution of vagal capsaicin‐sensitive substance P neurons with special reference to the trachea and lungs

1983 • 296 citations

THE CHOLINERGIC ‘PITFALL’: ACETYLCHOLINE, A UNIVERSAL CELL MOLECULE IN BIOLOGICAL SYSTEMS, INCLUDING HUMANS

1999 • 292 citations

Quantal acetylcholine release at the vertebrate neuromuscular junction.

1994 • 277 citations

Respiratory reflexes from the trachea and bronchi of the cat

1954 • 273 citations

Nerve supply to the lungs.

1979 • 271 citations

Non-neuronal acetylcholine, a signalling molecule synthezised by surface cells of rat and man

1997 • 270 citations

Human Keratinocytes Synthesize, Secrete, and Degrade Acetylcholine

1993 • 268 citations

CHOLINESTERASES IN THE BLOOD OF MAN

1940 • 256 citations

Muscarinic receptor subtypes in airways

1993 • 254 citations

Über humorale Übertragbarkeit der Herznervenwirkung

1926 • 253 citations

Modulation of neurotransmission in airways

1992 • 247 citations

Biological Functions of Keratinocyte Cholinergic Receptors

1997 • 244 citations

Human and Rodent Bronchial Epithelial Cells Express Functional Nicotinic Acetylcholine Receptors

1998 • 233 citations

Progress in Brain Research

1995 • 226 citations

The presence of histamine and acetylcholine in the spleen of the ox and the horse

1929 • 225 citations

Asthma: Basic Mechanisms and Clinical Management

1989 • 210 citations

Cholinergic systems in non-nervous tissues.

1978 • 206 citations

Ultrastructural localization of choline acetyltransferase in vascular endothelial cells in rat brain

1985 • 204 citations

The Cholinergic Gene Locus

1998 • 201 citations

Asthma : basic mechanisms and clinical management

1992 • 199 citations

Fundamental Mechanisms in the Release of Catecholamines

1972 • 192 citations

Pharmacological characterization of the acetylcholine transport system in purified Torpedo electric organ synaptic vesicles.

1983 • 181 citations

A unique gene organization for two cholinergic markers, choline acetyltransferase and a putative vesicular transporter of acetylcholine.

1994 • 179 citations

Parainfluenza virus infection damages inhibitory M₂ muscarinic receptors on pulmonary parasympathetic nerves in the guinea‐pig

1991 • 176 citations

The Pulmonary Circulation and Interstitial Space.

1970 • 173 citations

Reflex effects of upper airway irritation on total lung resistance and blood pressure

1962 • 172 citations

Choline Acetyltransferase: Celebrating Its Fiftieth Year

1994 • 167 citations

The vesicular acetylcholine transport system

1987 • 167 citations

The synthesis of acetylcholine in skeletal muscles of the rat

1982 • 166 citations

Cholinergic neurons and terminal fields revealed by immunohistochemistry for the vesicular acetylcholine transporter. II. The peripheral nervous system

1998 • 160 citations

Evidence for the Regulation of Phytochrome-mediated Processes in Bean Roots by the Neurohumor, Acetylcholine

1970 • 160 citations

Activation of Keratinocyte Nicotinic Cholinergic Receptors Stimulates Calcium Influx and Enhances Cell Differentiation

1996 • 158 citations

Airway epithelium: more than just a barrier!

1998 • 156 citations

The Pathobiology of Bronchial Asthma

1992 • 154 citations

Human placental cholinergic system

1976 • 152 citations

The exocytotic fusion pore and neurotransmitter release

1994 • 140 citations

Localization of Muscarinic Receptor Subtype mRNAs in Human Lung

1992 • 136 citations

Coregulation of Two Embedded Gene Products, Choline Acetyltransferase and the Vesicular Acetylcholine Transporter

1995 • 133 citations

Neuroendocrine cells and nerves of the lung

1993 • 129 citations

Choline and carnitine acetyltransferases of heart

1973 • 127 citations

Über humorale übertragbarkeit der Herznervenwirkung

1924 • 122 citations

Cholinergic Augmentation of Lymphocyte-Mediated Cytotoxicity. A Study of the Cholinergic Receptor of Cytotoxic T Lymphocytes

1974 • 122 citations

Microtubule-Dependent Vesicle Transport: Modulation of Channel and Transporter Activity in Liver and Kidney

1998 • 120 citations

Is an acetylcholine transport system responsible for nonquantal release of acetylcholine at the rodent myoneural junction?

1985 • 117 citations

Immunoregulatory role of neurotransmitters

1996 • 117 citations

Intra-epithelial nerves in normal rat airways: a quantitative electron microscopic study.

1973 • 116 citations

Acetylcholine, a New Active Principle of Ergot

1914 • 115 citations

Inhibition of Muscarinic Receptor‐Stimulated Glial Cell Proliferation by Ethanol

1996 • 113 citations

Flash photolysis of caged inositol 1,4,5-trisphosphate activates plasma membrane calcium current in human T cells.

1993 • 112 citations

Acetylcholine synthesis in neurons

1978 • 110 citations

Rat lymphocytes produce and secrete acetylcholine in dependence of differentiation and activation

1998 • 107 citations

Goblet cell degranulation in isolated canine tracheal epithelium: response to exogenous ATP, ADP, and adenosine

1992 • 104 citations

Regulation of Cl⁻ and K⁺ Channels in Airway Epithelium

1990 • 103 citations

Localization and synthesis of acetylcholine in human leukemic T cell lines

1996 • 103 citations

Neural Mechanisms in Asthma

1991 • 103 citations

Neural control of goblet cell secretion in guinea pig airways

1990 • 101 citations

Induction of choline acetyltransferase mRNA in human mononuclear leukocytes stimulated by phytohemagglutinin, a T-cell activator

1998 • 98 citations

Characterization of the muscarinic receptor subtype involved in phosphoinositide metabolism in bovine tracheal smooth muscle

1990 • 97 citations

The effects of irritation at various levels of the airway upon tracheal mucus secretion in the cat.

1976 • 96 citations

Acetylcholine synthesis and muscarinic receptor subtype mRNA expression in T-lymphocytes

1998 • 89 citations

Bradykinin stimulates bronchial epithelial cells to release neutrophil and monocyte chemotactic activity

1995 • 88 citations

Acetylcholine and ciliary movement in the gill plates of Mytilus edulis

1953 • 87 citations

Motor control of pulmonary airways studied by nerve stimulation

1965 • 86 citations

Cholinergic receptors of lymphocytes

1989 • 84 citations

Ultrastructural studies on the neuromuscular control of human tracheal and bronchial muscle

1986 • 84 citations

Keratinocyte Muscarinic Acetylcholine Receptors: Immunolocalization and Partial Characterization

1995 • 83 citations

Choline Acetyltransferase and the Synthesis of Acetylcholine

1988 • 80 citations

Tracheal submucosal gland serous cells stimulated in vitro with adrenergic and cholinergic agonists A morphometric study

1981 • 76 citations

Sensitive nicotinic and mixed nicotinic-muscarinic receptors in insect neurosecretory cells

1990 • 76 citations

Expression of choline acetyltransferase mRNA in spermatogenic cells results in an accumulation of the enzyme in the postacrosomal region of mature spermatozoa.

1991 • 73 citations

Expression of alpha subunit genes of nicotinic acetylcholine receptors in human lymphocytes

1996 • 72 citations

Identification of Acetylcholine and Related Esters of Biological Origin

1963 • 69 citations

Stimulation of ciliary beat frequency by autonomic agonists: in vivo

1988 • 67 citations

Mechanisms of mitogen-activated protein kinase activation by nicotine in small-cell lung carcinoma cells

1997 • 66 citations

Agarose Gel Keratinocyte Outgrowth System as a Model of Skin Re-epithelization: Requirement of Endogenous Acetylcholine for Outgrowth Initiation

1993 • 66 citations

The synaptic vesicle and its targets

1995 • 66 citations

Nervous Control of the Pulmonary Circulation

1980 • 66 citations

Physiology and Pharmacology of the Airways

1981 • 65 citations

The effect of vasoactive intestinal peptide on smooth muscle tone and mucus secretion from the ferret trachea

1987 • 65 citations

Physiologic responses and histamine release after nasal antigen challenge. Effect of atropine.

1994 • 64 citations

Neuromuscular structure and function in the airways.

1979 • 64 citations

Histochemical localization of neurohumors in a sponge

1966 • 63 citations

A microelectrode study of responses to secretagogues by epithelial cells on villus and crypt of rat small intestine

1989 • 62 citations

Acetylcholine synthesis in neurons

1979 • 62 citations

Adrenergic suppression of peripheral blood T cell reactivity in the rat is due to activation of peripheral α2-receptors

1995 • 60 citations

Endogenous tachykinins facilitate transmission through parasympathetic ganglia in guinea‐pig trachea

1993 • 60 citations

Cholinergic activation of Cl− secretion in rat colonic epithelia

1995 • 60 citations

Continuous in vivo treatment with catecholamines suppresses in vitro reactivity of rat peripheral blood T-lymphocytes via α-mediated mechanisms

1992 • 59 citations

Regulation of ciliary beat frequency by autonomic mechanisms: in vitro

1988 • 58 citations

ACETYLCHOLINE IN NORMAL AND DISEASED SKIN.

1962 • 58 citations

Asthma

1994 • 58 citations

CILIARY MOVEMENT AND ACETYLCHOLINE

1952 • 58 citations

Degradation of acetylcholine in human airways: role of butyrylcholinesterase

1993 • 56 citations

The effects of epithelium removal on the actions of cholinomimetic drugs in opened segments and perfused tubular preparations of guinea‐pig trachea

1990 • 55 citations

Innervation of airway smooth muscle. Efferent mechanisms

1987 • 55 citations

Functional and Molecular Characterization of a Muscarinic Receptor Type and Evidence for Expression of Choline-Acetyltransferase and Vesicular Acetylcholine Transporter in Human Granulosa-Luteal Cells1

1999 • 54 citations

Facilitatory effects of selective agonists for tachykinin receptors on cholinergic neurotransmission: evidence for species differences

1994 • 54 citations

Activation of nicotinic acetylcholine receptors increases the rate of fusion of cultured human myoblasts.

1995 • 54 citations

Metachronal activity of cultured mucociliary epithelium under normal and stimulated conditions

1994 • 53 citations

The Pulmonary Circulation and Interstitial Space

1969 • 53 citations

Correlation of Vasoactive Intestinal Peptide and Nitric Oxide Synthase with Choline Acetyltransferase in the Airway Innervation

2006 • 53 citations

Regulation of sodium absorption by canine tracheal epithelium.

1987 • 53 citations

In Vivo Production and Release of Acetylcholine from Primary Fibroblasts Genetically Modified to Express Choline Acetyltransferase

1993 • 52 citations

The parasympathetic nervous system takes part in the immuno-neuroendocrine dialogue

1991 • 51 citations

Acetylcholine via Muscarinic Receptors Inhibits Histamine Release from Human Isolated Bronchi

1997 • 51 citations

A cholinergic receptor site on murine lymphocytes with novel binding characteristics

1984 • 50 citations

Expression of Choline Acetyltransferase mRNA and Protein in T-Lymphocytes.

1995 • 50 citations

Glucocorticoids mediate reduction of epithelial acetylcholine content in the airways of rats and humans

1998 • 49 citations

Phorbol ester stimulates acetylcholine synthesis in cultured endothelial cells isolated from porcine cerebral microvessels

1994 • 49 citations

Neural and non-neural acetylcholine in the rat diaphragm

1982 • 47 citations

Localization of cholinergic nerves in lower airways of guinea pigs using antisera to choline acetyltransferase

1997 • 46 citations

Acetyl-coenzyme A and coenzyme A analogues. Their effects on rat brain choline acetyltransferase

1977 • 45 citations

Über den Nachweis von Hormonen in einzelligen Tieren

1936 • 44 citations

Human placental cholinergic system: depression of the uptake of alpha-aminoisobutyric acid in isolated human placental villi by choline acetyltransferase inhibitors.

1981 • 44 citations

The synthesis and release of acetylcholine in normal and denervated rat diaphragms during incubation in vitro

1983 • 44 citations

Synthesis of acetylcholine by endothelial cells isolated from rat brain cortex capillaries

1987 • 44 citations

Acetylcholine and nicotine stimulate the release of granulocyte-macrophage colony stimulating factor from cultured human bronchial epithelial cells

1998 • 44 citations

Muscarinic cholinergic binding sites on rat lymphocytes

1988 • 42 citations

Synthesis of acetylcholine by non-nervous tissue.

1946 • 42 citations

Innervation of Airway Smooth Muscle

1987 • 41 citations

Occurrence of light-dependent acetylcholine concentrations in higher plants

1974 • 41 citations

Physiology and pharmacology of the airways

1980 • 40 citations

The keratinocyte cholinergic system with acetylcholine as an epidermal cytotransmitter

1997 • 39 citations

The innervation of the trachea and extrapulmonary bronchi of the mouse

1984 • 39 citations

Intracellular calcium in canine cultured tracheal smooth muscle cells is regulated by M₃ muscarinic receptors

1993 • 38 citations

THE PRESENCE OF ACETYLCHOLINE IN TRYPANOSOMA RHODESIENSE AND ITS ABSENCE FROM PLASMODIUM GALLINACEUM

1949 • 38 citations

Effect of acetyl choline on ion transport in sheep tracheal epithelium

1994 • 37 citations

Innervation of Airway Smooth Muscle: Fine Structure

1987 • 35 citations

Muscarinic Receptor Subtypes in Lung: Clinical Implications

1990 • 33 citations

Response of lymphocyte guanyl cyclase to propranolol, noradrenaline, thymoxamine, and acetylcholine in extrinsic bronchial asthma.

1975 • 32 citations

The internal calcium store in airway muscle: Emptying, refilling and chloride

1992 • 32 citations

Irsogladine activates gap-junctional intercellular communication through M1 muscarinic acetylcholine receptor.

1995 • 30 citations

Release of [3H]acetylcholine in human isolated bronchi. Effect of indomethacin on muscarinic autoinhibition.

1995 • 30 citations

Mixed nicotinic and muscarinic features of cholinergic receptor coupled to secretion in bovine chromaffin cells.

1991 • 28 citations

IDENTIFICATION OF ACETYLCHOLINE, HISTAMINE, AND 5-HYDROXYTRYPTAMINE IN GIRARDINIA HETEROPHYLLA (DECNE.)

1966 • 27 citations

Immunopharmacology of epithelial barriers

1994 • 27 citations

Intact human lymphocyte membranes respond to muscarinic receptor stimulation by oxotremorine with marked changes in microviscosity and an increase in cyclic GMP

1985 • 26 citations

Effects of tetrodotoxin on chloride secretion in rabbit distal colon: tissue and cellular studies

1990 • 26 citations

Nasal glandular secretory response to cholinergic stimulation in humans and guinea pigs

1991 • 25 citations

Peripheral Airway Ganglia

1987 • 25 citations

Localization of a 900-bp-long fragment of the human choline acetyltransferase gene to 10q11.2 by nonradioactive in situ hybridization

1991 • 25 citations

The High-Affinity Choline Uptake System

1988 • 25 citations

Transient cholinergic glycoconjugate secretion from swine tracheal submucosal gland cells

1992 • 24 citations

Catecholamine affects acetylcholine release in trachea: alpha 2-mediated inhibition and beta 2-mediated augmentation

1995 • 24 citations

Release of [3H]acetylcholine from the isolated rat or guinea-pig trachea evoked by preganglionic nerve stimulation; a comparison with transmural stimulation

1991 • 23 citations

Regulation of acetylcholine hydrolysis in canine tracheal smooth muscle

1991 • 23 citations

Enhancement of quantal transmitter release and mediatophore expression by cyclic AMP in fibroblasts loaded with acetylcholine

1996 • 22 citations

Pharmacology of Asthma

1991 • 22 citations

Actions of thiocyanate and N-phenylmaleimide on volume-responsive Na and K transport in dog red cells

1992 • 22 citations

Capsaicin-activated bronchial- and alveolar-initiated pathways regulating tracheal ciliary beat frequency

1994 • 20 citations

Effects of quaternary ammonium compounds on choline entry into the rat diaphragm muscle fibre

1972 • 19 citations

The background of the muscarinic system

1995 • 19 citations

Update: pharmacology of airway secretion.

1994 • 18 citations

Muscarinic receptor subtypes in lung

1992 • 17 citations

Adrenergic and cholinergic receptors in submucosal glands of the ferret trachea: autoradiographic localization.

1983 • 16 citations

Regulation of goblet cell degranulation in isolated pancreatic ducts

1995 • 15 citations

Cholinergic mechanisms in Planaria Torva

1979 • 15 citations

Choline Acetyltransferase

2003 • 13 citations

Muscarinic receptors of the vascular bed: radioligand binding studies on bovine splenic veins.

1986 • 13 citations

Ultrastructure and biophysics of acetylcholine release: Central role of the mediatophore

1993 • 12 citations

Isolation and sub-chromosomal localization of a DNA fragment of the human choline acetyltransferase gene

1991 • 12 citations

Localization of the choline acetyltransferase (CHAT) gene to human chromosome 10

1990 • 12 citations

Evidence for muscarinic receptors in endothelial cells from combined functional and binding studies

1990 • 12 citations

Blocking by 2,4,6-triaminopyrimidine of increased tight junction permeability induced by acetylcholine in the pancreas

1980 • 11 citations

Effects of cholinergic drugs on uptake of [14C]-α-aminoisobutyric acid into fragments of human term placenta

1978 • 10 citations

Physiology of the Pulmonary Circulation

1971 • 8 citations

Choline acetyltransferase-like immunofluorescence in epidermis of human skin.

1993 • 7 citations

Chapter 18 Muscarinic receptor activated Ca2+channels in non-excitable cells

1996 • 7 citations

Muscarinic stimulation of gallbladder epithelium. I. Electrophysiology and signaling mechanisms

1993 • 6 citations

Effect of inhaled steroids on cholinergic transmission in human isolated bronchi

1995 • 5 citations

Deleted Work

1955 • 0 citations