Human and Rodent Bronchial Epithelial Cells Express Functional Nicotinic Acetylcholine Receptors

Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches

1981 • 18,584 citations

Detection of mRNAs in sea urchin embryos by in situ hybridization using asymmetric RNA probes

1984 • 1,638 citations

Mortality from tobacco in developed countries: indirect estimation from national vital statistics

1992 • 1,416 citations

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.

1993 • 543 citations

Assembly of Human Neuronal Nicotinic Receptor α5 Subunits with α3, β2, and β4 Subunits

1996 • 338 citations

Neurons assemble acetylcholine receptors with as many as three kinds of subunits while maintaining subunit segregation among receptor subtypes

1993 • 303 citations

Comparative pharmacology of epibatidine: a potent agonist for neuronal nicotinic acetylcholine receptors.

1995 • 284 citations

Non-neuronal acetylcholine, a signalling molecule synthezised by surface cells of rat and man

1997 • 270 citations

Human Keratinocytes Synthesize, Secrete, and Degrade Acetylcholine

1993 • 268 citations

Neuronal nicotinic receptors: Molecular organization and regulations

1995 • 254 citations

Agonist-induced myopathy at the neuromuscular junction is mediated by calcium.

1979 • 242 citations

Cholinergic systems in non-nervous tissues.

1978 • 206 citations

A Nicotinic Acetylcholine Receptor Regulating Cell Adhesion and Motility Is Expressed in Human Keratinocytes

1995 • 206 citations

A mutated acetylcholine receptor subunit causes neuronal degeneration in C. elegans

1995 • 203 citations

Chronic nicotine exposure differentially affects the function of human alpha3, alpha4, and alpha7 neuronal nicotinic receptor subtypes.

1997 • 174 citations

Nicotine enhances expression of the alpha 3, alpha 4, alpha 5, and alpha 7 nicotinic receptors modulating calcium metabolism and regulating adhesion and motility of respiratory epithelial cells.

1997 • 173 citations

Quantitative measurement of calcium flux through muscle and neuronal nicotinic acetylcholine receptors

1994 • 162 citations

The Nicotinic Acetylcholine Receptor: Structure and Autoimmune Pathology

1994 • 149 citations

The Biology of nicotine dependence

1990 • 140 citations

The Global Tobacco Epidemic

1995 • 130 citations

The human muscle nicotinic acetylcholine receptor alpha-subunit exist as two isoforms: a novel exon.

1990 • 112 citations

Calcium‐modulated contractile proteins associated with the eucaryotic centrosome

1986 • 108 citations

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. III. Agonist actions of the novel alkaloid epibatidine and analysis of type II current.

1995 • 82 citations

Effects of Chronic Nicotinic Ligand Exposure on Functional Activity of Nicotinic Acetylcholine Receptors Expressed by Cells of the PC12 Rat Pheochromocytoma or the TE671/RD Human Clonal Line

1991 • 81 citations

Acute Effects of Smoking during Modified Sham Feeding in Duodenal Ulcer Patients: An Analysis of Nicotine, Acid Secretion, Gastrin, Catecholamines, Epidermal Growth Factor, Prostaglandin E₂, and Bile Acids

1993 • 67 citations

Calcium-mediated myopathy at neuromuscular junctions of normal and dystrophic muscle

1982 • 65 citations

?-Subunits co-determine the sensitivity of rat neuronal nicotinic receptors to antagonists

1995 • 58 citations

Improved technique for studying ion channels expressed in Xenopus oocytes, including fast superfusion

1994 • 56 citations

Myasthenic Syndromes Attributed to Mutations Affecting the Epsilon Subunit of the Acetylcholine Receptora

1993 • 42 citations

β43′: An Enhancer Displaying Neural-Restricted Activity Is Located in the 3′-Untranslated Exon of the Rat Nicotinic Acetylcholine Receptor β4 Gene

1997 • 42 citations

AmpliGrease: "hot start" PCR using petroleum jelly.

1994 • 35 citations

Cryptic epitopes on the nicotinic acetylcholine receptor are recognized by autoreactive CD4+ cells.

1993 • 34 citations

The biology of nicotine dependence (Ciba foundation symposium 152)

1991 • 30 citations

Release of [3H]acetylcholine in human isolated bronchi. Effect of indomethacin on muscarinic autoinhibition.

1995 • 30 citations

Antibodies as Tools to Study the Structure of Membrane Proteins: The Case of the Nicotinic Acetylcholine Receptor

1996 • 23 citations

Localization of [14C]nitrosonornicotine in tissues of the mouse.

1980 • 16 citations

Monoclonal antibodies against synthetic sequences of the nicotinic receptor cross-react fully with the native receptor and reveal the transmembrane disposition of their epitopes

1993 • 12 citations

Designing PCR Primers to Amplify Specific Members or Subgroups of Multigene Families

2003 • 9 citations

A T-Linker Strategy for Modification and Directional Cloning of PCR Products

2003 • 2 citations

A T-Linker Strategy for Modification and Directional Cloning of PCR Products

2003 • 2 citations

Deleted Work

1955 • 0 citations