Convergence of Redox-Sensitive and Mitogen-Activated Protein Kinase Signaling Pathways in Tumor Necrosis Factor-α–Mediated Monocyte Chemoattractant Protein-1 Induction in Vascular Smooth Muscle Cells

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Identification of a Novel Inhibitor of Mitogen-activated Protein Kinase Kinase

1998 • 3,026 citations

Angiotensin II stimulates NADH and NADPH oxidase activity in cultured vascular smooth muscle cells.

1994 • 2,753 citations

Requirement for Generation of H ₂ O ₂ for Platelet-Derived Growth Factor Signal Transduction

1995 • 2,505 citations

How MAP Kinases Are Regulated

1995 • 1,742 citations

Vascular cell adhesion molecule-1 (VCAM-1) gene transcription and expression are regulated through an antioxidant-sensitive mechanism in human vascular endothelial cells.

1993 • 1,079 citations

Parallel signal processing among mammalian MAPKs

1995 • 1,015 citations

MAPKs: new JNK expands the group

1994 • 949 citations

p22 Is a Critical Component of the Superoxide-generating NADH/NADPH Oxidase System and Regulates Angiotensin IIinduced Hypertrophy in Vascular Smooth Muscle Cells

1996 • 768 citations

Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats.

1997 • 683 citations

p38 and Extracellular Signal-regulated Kinase Mitogen-activated Protein Kinase Pathways Are Required for Nuclear Factor-κB p65 Transactivation Mediated by Tumor Necrosis Factor

1998 • 678 citations

p38 Mitogen-activated Protein Kinase Is a Critical Component of the Redox-sensitive Signaling Pathways Activated by Angiotensin II

1998 • 657 citations

Apoptosis Induced by Withdrawal of Trophic Factors Is Mediated by p38 Mitogen-activated Protein Kinase

1997 • 471 citations

Big Mitogen-activated Protein Kinase 1 (BMK1) Is a Redox-sensitive Kinase

1996 • 445 citations

Angiotensin II Induces Monocyte Chemoattractant Protein-1 Gene Expression in Rat Vascular Smooth Muscle Cells

1998 • 388 citations

Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways

1999 • 386 citations

Stress-activated Protein Kinases: Activation, Regulation and Function

1997 • 327 citations

Tumour necrosis factor α activates a p22phox-based NADH oxidase in vascular smooth muscle

1998 • 313 citations

Oxygen radicals as second messengers for expression of the monocyte chemoattractant protein, JE/MCP-1, and the monocyte colony-stimulating factor, CSF-1, in response to tumor necrosis factor-alpha and immunoglobulin G. Evidence for involvement of reduced nicotinamide adenine dinucleotide phosphate (NADPH)-dependent oxidase.

1993 • 275 citations

Platelet-Derived Growth Factor–Stimulated Superoxide Anion Production Modulates Activation of Transcription Factor NF-κB and Expression of Monocyte Chemoattractant Protein 1 in Human Aortic Smooth Muscle Cells

1997 • 257 citations

Cyclic Strain–Induced Monocyte Chemotactic Protein-1 Gene Expression in Endothelial Cells Involves Reactive Oxygen Species Activation of Activator Protein 1

1997 • 246 citations

Cytokine-mediated Induction of Ceramide Production Is Redox-sensitive

1998 • 206 citations

Role of Activating Protein-1 in the Regulation of the Vascular Cell Adhesion Molecule-1 Gene Expression by Tumor Necrosis Factor-α

1998 • 190 citations

Activation of nuclear factor-κB correlates with MCP-1 expression by human mesangial cells

1995 • 185 citations

A Redox-triggered Ras-Effector Interaction

1998 • 182 citations

p38 Mitogen-activated Protein Kinase Down-regulates Nitric Oxide and Up-regulates Prostaglandin E2 Biosynthesis Stimulated by Interleukin-1β

1997 • 181 citations

Local Expression of Inflammatory Cytokines in Human Atherosclerotic Plaques

1994 • 178 citations

Mitogen-activated Protein (MAP) Kinase Is Regulated by the MAP Kinase Phosphatase (MKP-1) in Vascular Smooth Muscle Cells

1995 • 177 citations

Angiotensin II down-regulates the vascular smooth muscle AT1 receptor by transcriptional and post-transcriptional mechanisms: evidence for homologous and heterologous regulation.

1995 • 175 citations

The MKK6/p38 Stress Kinase Cascade Is Critical for Tumor Necrosis Factor-–Induced Expression of Monocyte-Chemoattractant Protein-1 in Endothelial Cells

1999 • 160 citations

TNF-α–Induced Migration of Vascular Smooth Muscle Cells Is MAPK Dependent

1999 • 157 citations

Differential Regulation of Interleukin-8 and Intercellular Adhesion Molecule-1 by H2O2 and Tumor Necrosis Factor-α in Endothelial and Epithelial Cells

1997 • 156 citations

Tumour necrosis factor α and interleukin 1 signalling: do MAPKK kinases connect it all?

1997 • 154 citations

TNF Regulates the In Vivo Occupancy of Both Distal and Proximal Regulatory Regions of the MCP-1/JE Gene

1996 • 134 citations

Nuclear factor-kappa B p65 mediates the assembly and activation of the TNF-responsive element of the murine monocyte chemoattractant-1 gene.

1999 • 112 citations

Antioxidants inhibit tumor necrosis factor-alpha mediated stimulation of interleukin-8, monocyte chemoattractant protein-1, and collagenase expression in cultured human synovial cells.

1996 • 109 citations

Oxidant-Mediated Activation of Mitogen- Activated Protein Kinases and Nuclear Transcription Factors in the Cardiovascular System

1998 • 108 citations

Effect of Probucol Treatment on Gene Expression of VCAM-1, MCP-1, and M-CSF in the Aortic Wall of LDL Receptor–Deficient Rabbits During Early Atherogenesis

1997 • 100 citations

Characterization of phosphatidylinositol-specific phospholipase C from cultured vascular smooth muscle cells

1991 • 97 citations

Nuclear Factor-κB p65 Mediates the Assembly and Activation of the TNF-Responsive Element of the Murine Monocyte Chemoattractant-1 Gene

1999 • 93 citations

Modulation of oxidant lung injury by using liposome-entrapped superoxide dismutase and catalase.

1985 • 92 citations

Apoptosis and Free Radicals

1996 • 79 citations

Tumour necrosis factor α and interleukin 1 signalling: do MAPKK kinases connect it all?

1997 • 72 citations

THE MITOGEN-ACTIVATED PROTEIN KINASE p38 IS NECESSARY FOR INTERLEUKIN-1β-INDUCED MONOCYTE CHEMOATTRACTANT PROTEIN 1 EXPRESSION BY HUMAN MESANGIAL CELLS

1999 • 67 citations

Cytokines Regulate Genes Involved in Atherogenesis^a

1994 • 67 citations

MODULATION OF IL-1-INDUCED CHEMOKINE EXPRESSION IN HUMAN MESANGIAL CELLS THROUGH ALTERATIONS IN REDOX STATUS

1997 • 57 citations

Regulation of monocyte chemoattractant protein 1 by cytokines and oxygen free radicals in rat hepatic fat-storing cells

1996 • 52 citations

Production of monocyte chemoattractant protein-1 by bovine glomerular endothelial cells

1995 • 49 citations

Role of tumor necrosis factor-alpha on mesangial cell MCP-1 expression and monocyte migration

1996 • 46 citations

Endothelin-Mediated Positive Inotropic Effect Induced by Reactive Oxygen Species in Isolated Cardiac Muscle

1995 • 41 citations

Arachidonic acid activates Jun N-terminal kinase in vascular smooth muscle cells

1998 • 40 citations

Involvement of Reactive Oxygen Species in the Induction of Chemokine JE/MCP-1 Gene by Phorbol-12-myristate-13-acetate in Balb 3T3 Cells.

1997 • 12 citations