Identification of dithiolethione-inducible gene-1 as a leukotriene B4 12-hydroxydehydrogenase: implications for chemoprevention

Helicobacter pyloriInfection and the Risk of Gastric Carcinoma

1991 • 3,869 citations

Prooxidant States and Tumor Promotion

1985 • 2,541 citations

Inflammation. Basic principles and clinical correlates

1989 • 2,424 citations

Damage to DNA by reactive oxygen and nitrogen species: role in inflammatory disease and progression to cancer

1996 • 2,327 citations

Leukotriene B, a potent chemokinetic and aggregating substance released from polymorphonuclear leukocytes

1980 • 2,099 citations

Ulcerative Colitis and Colorectal Cancer

1990 • 1,755 citations

Amino acid analysis by reverse-phase high-performance liquid chromatography: Precolumn derivatization with phenylisothiocyanate

1984 • 1,616 citations

Chemoprevention of Cancer

2008 • 1,269 citations

A G-protein-coupled receptor for leukotriene B4 that mediates chemotaxis

1997 • 990 citations

Enhanced Synthesis of Leukotriene B4 by Colonic Mucosa in Inflammatory Bowel Disease

1984 • 749 citations

An overview of the relationship between oxidative stress and chemical carcinogenesis

1991 • 378 citations

Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma.

1994 • 307 citations

DNA Strand Breakage in Human Leukocytes Exposed to a Tumor Promoter, Phorbol Myristate Acetate

1982 • 255 citations

Activated neutrophils induce prolonged DNA damage in neighboring cells

1988 • 243 citations

Properties of leukotriene B4 20-hydroxylase from polymorphonuclear leukocytes.

1984 • 236 citations

Inhibition by dietary curcumin of azoxymethane-induced ornithine decarboxylase, tyrosine protein kinase, arachidonic acid metabolism and aberrant crypt foci formation in the rat colon

1993 • 218 citations

[39] The generation of chemiluminescence (CL) by phagocytic cells

1978 • 215 citations

Food Phytochemicals for Cancer Prevention I

1993 • 124 citations

Antioxidant-Inducible Genes

1996 • 111 citations

Enzymatic inactivation of leukotriene B4 by a novel enzyme found in the porcine kidney. Purification and properties of leukotriene B4 12-hydroxydehydrogenase.

1993 • 108 citations

Myeloperoxidase-enhanced formation of (±)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a] pyrene adducts in lung tissue in vitro: a role of pulmonary inflammation in the bioactivation of a procarcinogen

1992 • 102 citations

Oltipraz: Clinical opportunities for cancer chemoprevention

1995 • 83 citations

cDNA Cloning, Expression, and Mutagenesis Study of Leukotriene B4 12-Hydroxydehydrogenase

1996 • 82 citations

Isolation of cDNAs representing dithiolethione-responsive genes

1996 • 79 citations

Expression of Ah receptor (TCDD receptor) during human monocytic differentiation

1995 • 74 citations

Neutrophil oxygen radical generation. Synergistic responses to tumor necrosis factor and mono/polyunsaturated fatty acids.

1996 • 74 citations

Induction of hepatic heme oxygenase-1 and ferritin in rats by cancer chemopreventive dithiolethiones

1996 • 68 citations

Mechanism for the formation of dihydro metabolites of 12-hydroxyeicosanoids. Conversion of leukotriene B4 and 12-hydroxy-5,8,10,14-eicosatetraenoic acid to 12-oxo intermediates.

1991 • 54 citations

Metabolism of 6-trans isomers of leukotriene B4 to dihydro products by human polymorphonuclear leukocytes.

1988 • 35 citations

The Development of Secondary Pathology with free Radical Reactions as a Threshold Mechanism

1983 • 34 citations

Comparison of oxidant-generation and BP-diol activation by bone marrow cells from and mice: Implications for risk of bone marrow toxicity induced by polycyclic hydrocarbons

1992 • 17 citations

Enhanced expression, purification, and characterization of a novel class α glutathione S-transferase isozyme appearing in rabbit hepatic cytosol following treatment with 4-picoline

1992 • 11 citations

Chemoprotection by 1,2-dithiole-3-thiones.

1994 • 8 citations

Untitled

1997 • 4 citations