Chemoprevention of Cancer

The Role of Glutathione and Glutathione S-Transferases in the Metabolism of Chemical Carcinogens and Other Electrophilic Agents

1979 • 1,179 citations

Some current perspectives on chemical carcinogenesis in humans and experimental animals: Presidential Address.

1978 • 938 citations

Role of retinoids in differentiation and carcinogenesis.

1983 • 780 citations

Inhibition of neoplasia by minor dietary constituents.

1983 • 479 citations

Correlation of the inhibition by retinoids of tumor promoter-induced mouse epidermal ornithine decarboxylase activity and of skin tumor promotion.

1979 • 361 citations

The Metabolic Activation of Carcinogenic Aromatic Amines and Amides1

2015 • 349 citations

Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo(a)pyrene by dietary antioxidants.

1978 • 338 citations

STUDIES ON THE MECHANISM OF ACTION OF THE CHLORINATED DIBENZO‐p‐DIOXINS AND RELATED COMPOUNDS*

1979 • 336 citations

Antitumor Activity of <i>β</i>-Carotene, Canthaxanthin and Phytoene

1982 • 311 citations

Inhibition of Carcinogenic Effects of Polycyclic Hydrocarbons by Benzyl Isothiocyanate and Related Compounds2

1977 • 309 citations

Inhibitors of Chemical Carcinogenesis

1978 • 304 citations

Inhibition of the mutagenicity of bay-region diol epoxides of polycyclic aromatic hydrocarbons by naturally occurring plant phenols: Exceptional activity of ellagic acid

1982 • 269 citations

Pathways of Drug Metabolism,

1956 • 265 citations

Tumorigenesis in Mouse Skin: Inhibition by Synthetic Inhibitors of Proteases

1970 • 263 citations

Inhibition of Tumor Promotion by a Biomimetic Superoxide Dismutase

1983 • 256 citations

Inhibition of development of methylnitrosourea-induced rat colon tumors by indomethacin treatment.

1981 • 229 citations

Inhibitory effects of phenolic compounds on benzo(a)pyrene-induced neoplasia.

1980 • 224 citations

Inhibition of 12-O-tetradecanoylphorbol-13-acetate-induced tumor promotion and ornithine decarboxylase activity by quercetin: possible involvement of lipoxygenase inhibition

1983 • 217 citations

Inhibition of the carcinogenic action of benzo(a)pyrene by flavones.

1970 • 210 citations

Elevation of extrahepatic glutathione S-transferase and epoxide hydratase activities by 2(3)-tert-butyl-4-hydroxyanisole.

1979 • 200 citations

Protective effects of ellagic acid and other plant phenols on benzo[a]pyrene-induced neoplasia in mice

1983 • 171 citations

Inhibition of mouse skin tumor promotion by several inhibitors of arachidonic acid metabolism

1982 • 156 citations

Inhibitors of chemical carcinogens.

1980 • 152 citations

Inhibition of tumorigenesis in mouse skin by leupeptin, a protease inhibitor from Actinomycetes.

1972 • 142 citations

Bowman-Birk soybean protease inhibitor as an anticarcinogen.

1983 • 130 citations

Inhibition of 7,12-dimethylbenz[a]anthracene- and urethan-induced lung tumor formation in A/J mice by long-term treatment with dehydroepiandrosterone

1981 • 123 citations

Effects of antiinflammatory agents on mouse skin tumor promotion, epidermal DNA synthesis, phorbol ester-induced cellular proliferation, and production of plasminogen activator.

1977 • 117 citations

Caffeic and ferulic acid as blockers of nitrosamine formation

1984 • 116 citations

Inhibitory effect of antioxidants ethoxyquin and 2(3)-tert-butyl-4-hydroxyanisole on hepatic tumorigenesis in rats fed ciprofibrate, a peroxisome proliferator.

1984 • 107 citations

Brief Communication: Inhibition of Dimethylhydrazine-Induced Neoplasia of the Large Intestine by Disulfiram2

1975 • 103 citations

Inhibition of mouse skin tumor promotion and of promoter-stimulated epidermal polyamine biosynthesis by alpha-difluoromethylornithine.

1983 • 101 citations

Fluocinolone acetonide: A potent inhibitor of mouse skin tumor promotion and epidermal DNA synthesis

1977 • 93 citations

Protection against 3-methylcholanthrene-induced skin tumorigenesis in Balb/C mice by ellagic acid

1984 • 92 citations

Enhancement of liver microsome epoxide hydratase activity in rodents by treatment with 2(3)-tert-butyl-4-hydroxyanisole.

1978 • 83 citations

Factors influencing the anticarcinogenic efficacy of selenium in dimethylbenz[a]anthracene-induced mammary tumorigenesis in rats.

1981 • 79 citations

Inhibition by dietary selenium of colon cancer induced in the rat by bis(2-oxopropyl)nitrosamine.

1982 • 72 citations

Effects of Administration to Mice of Butylated Hydroxyanisole by Oral Intubation on Benzo[ a ]pyrene-Induced Pulmonary Adenoma Formation and Metabolism of Benzo[ a ]pyrene 2

1978 • 63 citations

Inhibitory effects of selenium on 1,2- dimethylhydrazine and methylazoxymethanol colon carcinogenesis.Correlative studies on selenium effects on the mutagenicity and sister chromatid exchange rates of selected carcinogens

1977 • 61 citations

Inhibition of 7,12-dimethylbenz(a)anthracene-induced rat mammary carcinogenesis by concomitant or postcarcinogen antioxidant exposure.

1984 • 59 citations

Formation of a mutagenic drug metabolite by intestinal microorganisms.

1978 • 57 citations

Effect of dietary selenium levels on 7,12-dimethylbenzanthracene-induced mouse mammary tumorigenesis

1983 • 50 citations

A Model Study of Fecapentaenes: Mutagens of Bacterial Origin with Alkylating Properties

1984 • 49 citations

The effects of two isomeric benzoflavones on aryl hydrocarbon hydroxylase and the toxicity and carcinogenicity of polycyclic hydrocarbons.

1972 • 42 citations

Induction of mouse epidermal ornithine decarboxylase activity and skin tumors by 7, 12-dimethylbenz[a]anthracene: modulation by retinoic acid and 7,8-benzoflavone

1980 • 41 citations

The reduction of tumor initiating activity and cell mediated mutagenicity of dimethylbenz[a]anthracene by a copper coordination compound

1984 • 38 citations

Timing of chemically induced neoplasia in mice revealed by the antineoplastic action of caffeine.

1980 • 36 citations

Inhibition of 7-bromomethylbenz[a]anthracene-promoted mouse skin tumor formation by retinoic acid and dexamethasone.

1983 • 34 citations

Controlling factors in urethan carcinogenesis in mice: effect of enzyme inducers and metabolic inhibitors.

1971 • 34 citations

Ascorbic Acid Inhibition of N-Nitroso Compound Formation in Chemical, Food, and Biological Systems

1981 • 32 citations

Short time interval effects of butylated hydroxyanisole on the metabolism of benzo(a)pyrene.

1980 • 31 citations

Inhibition of ultraviolet-B epidermal ornithine decarboxylase induction and skin carcinogenesis in hairless mice by topical indomethacin and triamcinolone acetonide.

1982 • 29 citations

Antiteratogenic effects of tumor inhibitors, caffeine, antipain, and retinoic acid in mice.

1983 • 29 citations

Inhibition of 1,2-Dimethylhydrazine-Induced Neoplasia of the Large Intestine in Female CF 1 Mice by Carbon Disulfide: Brief Communication 2

1978 • 20 citations

Effects of p-methoxyphenol and diet on carcinogen-induced neoplasia of the mouse forestomach.

1983 • 18 citations

Inhibiting effects of antipain on urethane-induced lung neoplasia in mice

1980 • 10 citations

Retinoids and Suppression of Carcinogenesis

1983 • 10 citations

Diazepam inhibition of phorbol ester tumor promotion

1983 • 7 citations