Back to search

Heme oxygenase‐1‐derived carbon monoxide protects hearts from transplant‐associated ischemia reperfusion injury

Data up to Jan 2025

Published2004
Citations196
References56

Total Citations Per Year

Abstract

References (56)

Tolerance, Danger, and the Extended Family

1994 • 4,654 citations

Bilirubin Is an Antioxidant of Possible Physiological Importance

1987 • 3,406 citations

The ferritins: molecular properties, iron storage function and cellular regulation

1996 • 2,572 citations

Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

2000 • 2,074 citations

The enzymatic conversion of heme to bilirubin by microsomal heme oxygenase.

1968 • 1,767 citations

Reperfusion injury induces apoptosis in rabbit cardiomyocytes.

1994 • 1,431 citations

Improved technique of heart transplantation in rats

1969 • 1,338 citations

Heme oxygenase-1: unleashing the protective properties of heme

2003 • 1,137 citations

Ferritin: a cytoprotective antioxidant strategem of endothelium.

1992 • 1,100 citations

Biliverdin reductase: A major physiologic cytoprotectant

2002 • 1,071 citations

Carbon Monoxide Generated by Heme Oxygenase 1 Suppresses Endothelial Cell Apoptosis

2000 • 970 citations

The heme synthesis and degradation pathways: role in oxidant sensitivity

2000 • 779 citations

Attenuation of Ischemia/Reperfusion Injury in Rats by a Caspase Inhibitor

1998 • 625 citations

Expression of heme oxygenase-1 can determine cardiac xenograft survival

1998 • 621 citations

Different Faces of the Heme-Heme Oxygenase System in Inflammation

2003 • 529 citations

Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury

2003 • 526 citations

Deleterious effects of oxygen radicals in ischemia/reperfusion. Resolved and unresolved issues.

1989 • 518 citations

Inhibition of platelet aggregation by carbon monoxide is mediated by activation of guanylate cyclase.

1987 • 466 citations

Carbon Monoxide Generated by Heme Oxygenase-1 Suppresses the Rejection of Mouse-to-Rat Cardiac Transplants

2001 • 455 citations

Cardiac-Specific Expression of Heme Oxygenase-1 Protects Against Ischemia and Reperfusion Injury in Transgenic Mice

2001 • 423 citations

Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure

2001 • 419 citations

Heme is a potent inducer of inflammation in mice and is counteracted by heme oxygenase

2001 • 413 citations

Paradoxical rescue from ischemic lung injury by inhaled carbon monoxide driven by derepression of fibrinolysis

2001 • 396 citations

Heme oxygenase-1-derived bilirubin ameliorates postischemic myocardial dysfunction

2000 • 393 citations

Identification of the CD4+ T cell as a major pathogenic factor in ischemic acute renal failure

2001 • 381 citations

Reperfusion injury of ischemic skeletal muscle is mediated by natural antibody and complement.

1996 • 378 citations

Oxidative stress and neutrophil activation—the two keystones of ischemia/reperfusion injury

2002 • 342 citations

Morphological and Molecular Characterization of Adult Cardiomyocyte Apoptosis During Hypoxia and Reoxygenation

2000 • 312 citations

Regulation of ferritin and heme oxygenase synthesis in rat fibroblasts by different forms of iron.

1991 • 309 citations

Heme Oxygenase-1-derived Carbon Monoxide Requires the Activation of Transcription Factor NF-κB to Protect Endothelial Cells from Tumor Necrosis Factor-α-mediated Apoptosis

2002 • 301 citations

Carbon Monoxide Inhibition of Apoptosis during Ischemia-Reperfusion Lung Injury Is Dependent on the p38 Mitogen-activated Protein Kinase Pathway and Involves Caspase 3

2003 • 283 citations

Carbon monoxide is a major contributor to the regulation of vascular tone in aortas expressing high levels of haeme oxygenase‐1

1998 • 239 citations

Ex vivoexposure to carbon monoxide prevents hepatic ischemia/reperfusion injury through p38 MAP kinase pathway

2002 • 227 citations

Heme Induces the Expression of Adhesion Molecules ICAM-1, VCAM-1, and E Selectin in Vascular Endothelial Cells

1997 • 225 citations

Fas pathway is a critical mediator of cardiac myocyte death and MI during ischemia-reperfusion in vivo

2003 • 210 citations

"Reperfusion injury" by oxygen-derived free radicals? Effect of superoxide dismutase plus catalase, given at the time of reperfusion, on myocardial infarct size, contractile function, coronary microvasculature, and regional myocardial blood flow.

1989 • 209 citations

Hemodynamic forces induce the expression of heme oxygenase in cultured vascular smooth muscle cells.

1997 • 204 citations

Heavy chain ferritin acts as an anti‐apoptotic gene that protects livers from ischemia‐reperfusion injury

2003 • 200 citations

Heme oxygenase-1 system in organ transplantation1

2002 • 199 citations

Cardiac functional improvement by a human Bcl-2 transgene in a mouse model of ischemia/reperfusion injury

2000 • 192 citations

Oxidative Stress Developed During the Reperfusion of Ischemic Myocardium Induces Apoptosis

1998 • 179 citations

HEME OXYGENASE-1 OVEREXPRESSION PROTECTS RAT HEARTS FROM COLD ISCHEMIA/REPERFUSION INJURY VIA AN ANTIAPOPTOTIC PATHWAY1

2002 • 158 citations

Modulation of Endothelial Cell Apoptosis by Heme Oxygenase-1-Derived Carbon Monoxide

2002 • 133 citations

The neutrophil as a mediator of myocardial ischemia-reperfusion injury: time to move on

2002 • 123 citations

Networking Antioxidants in the Isolated Rat Heart are Selectively Depleted by Ischemia-Reperfusion

1998 • 121 citations

COMPLEMENT DEPOSITION IN EARLY CARDIAC TRANSPLANT BIOPSIES IS ASSOCIATED WITH ISCHEMIC INJURY AND SUBSEQUENT REJECTION EPISODES1

1999 • 116 citations

PREVENTION OF LATE RENAL CHANGES AFTER INITIAL ISCHEMIA/REPERFUSION INJURY BY BLOCKING EARLY SELECTIN BINDING1

1997 • 110 citations

Role of intracellular antioxidant enzymes after in vivo myocardial ischemia and reperfusion

2003 • 91 citations

Extracellular adenosine levels and cellular energy metabolism in ischemically preconditioned rat heart

1998 • 67 citations

Genetic redox preconditioning differentially modulates AP-1 and NFκB responses following cardiac ischemia/reperfusion injury and protects against necrosis and apoptosis

2003 • 52 citations

Involvement of lipoproteins, free radicals, and calcium in cardiovascular disease processes.

1995 • 41 citations

Involvement of lipoproteins, free radicals, and calcium in cardiovascular disease processes

1995 • 30 citations

Enhanced expression and localization of heme oxygenase-1 during recovery phase of porcine stunned myocardium

1999 • 28 citations

Mitochondrial ATP-synthase activity in cardiomyocytes after aerobic-anaerobic metabolic transition

1992 • 24 citations

Untitled

1999 • 24 citations

Expression of heme oxygenase-1 by endothelial cells: a protective response to injury in transplantation

2000 • 8 citations

Cited By (0)

No citing papers found in database

Heme oxygenase‐1‐derived carbon monoxide protects hearts from transplant‐associated… (2004) – The FASEB Journal | Metascience Observatory Explorer