Downregulation of the vasopressin type 2 receptor after vasopressin-induced internalization: involvement of a lysosomal degradation pathway

β-Arrestin acts as a clathrin adaptor in endocytosis of the β2-adrenergic receptor

1996 • 1,329 citations

Distinct Membrane Domains on Endosomes in the Recycling Pathway Visualized by Multicolor Imaging of Rab4, Rab5, and Rab11

2000 • 987 citations

Role of β-Arrestin in Mediating Agonist-Promoted G Protein-Coupled Receptor Internalization

1996 • 938 citations

c-Cbl/Sli-1 regulates endocytic sorting and ubiquitination of the epidermal growth factor receptor

1998 • 865 citations

Differential Affinities of Visual Arrestin, βArrestin1, and βArrestin2 for G Protein-coupled Receptors Delineate Two Major Classes of Receptors

2000 • 835 citations

Regulation of Receptor Fate by Ubiquitination of Activated β ₂ -Adrenergic Receptor and β-Arrestin

2001 • 807 citations

Association of β-Arrestin with G Protein-coupled Receptors during Clathrin-mediated Endocytosis Dictates the Profile of Receptor Resensitization

1999 • 549 citations

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family.

1992 • 531 citations

Reduced temperature prevents transfer of a membrane glycoprotein to the cell surface but does not prevent terminal glycosylation

1983 • 504 citations

Agonist-promoted Ubiquitination of the G Protein-coupled Receptor CXCR4 Mediates Lysosomal Sorting

2001 • 456 citations

Epidermal growth factor: morphological demonstration of binding, internalization, and lysosomal association in human fibroblasts.

1978 • 358 citations

Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts.

1984 • 357 citations

Epidermal growth factor receptors

1981 • 352 citations

Rab4 and cellubrevin define different early endosome populations on the pathway of transferrin receptor recycling.

1996 • 338 citations

Antigen retrieval in cryostat tissue sections and cultured cells by treatment with sodium dodecyl sulfate (SDS)

1996 • 328 citations

Export from the Endoplasmic Reticulum Represents the Limiting Step in the Maturation and Cell Surface Expression of the Human δ Opioid Receptor

2000 • 285 citations

Regulation and Intracellular Trafficking Pathways of the Endothelin Receptors

2000 • 243 citations

Constitutive arrestin-mediated desensitization of a human vasopressin receptor mutant associated with nephrogenic diabetes insipidus

2000 • 235 citations

Dense core lysosomes can fuse with late endosomes and are re-formed from the resultant hybrid organelles

1997 • 234 citations

Nitric oxide and atrial natriuretic factor stimulate cGMP-dependent membrane insertion of aquaporin 2 in renal epithelial cells

2000 • 224 citations

Type-specific Sorting of G Protein-coupled Receptors after Endocytosis

2000 • 218 citations

Receptor-mediated endocytosis of epidermal growth factor by rat hepatocytes: receptor pathway.

1986 • 217 citations

Chimeric Forms of Furin and Tgn38 Are Transported from the Plasma Membrane to the Trans-Golgi Network via Distinct Endosomal Pathways

1999 • 211 citations

The importance of being acid: the role of acidification in intracellular membrane traffic

1992 • 183 citations

Constitutive and regulated membrane expression of aquaporin 1 and aquaporin 2 water channels in stably transfected LLC-PK1 epithelial cells.

1995 • 173 citations

The Cytoplasmic Tails of Protease-activated Receptor-1 and Substance P Receptor Specify Sorting to Lysosomes versusRecycling

1999 • 172 citations

Isolation and characterization of early endosomes, late endosomes and terminal lysosomes: their role in protein degradation

1996 • 170 citations

Mechanisms controlling EGF receptor endocytosis and degradation

2003 • 169 citations

Biochemical analysis of distinct Rab5- and Rab11-positive endosomes along the transferrin pathway

1999 • 157 citations

The Long and the Short Cycle

2001 • 153 citations

Protein Kinase A and G Protein-coupled Receptor Kinase Phosphorylation Mediates β-1 Adrenergic Receptor Endocytosis through Different Pathways

2003 • 150 citations

Localization of Furin to the trans-Golgi Network and Recycling from the Cell Surface Involves Ser and Tyr Residues within the Cytoplasmic Domain

1995 • 131 citations

A serine cluster prevents recycling of the V2 vasopressin receptor

1998 • 128 citations

Regulation of V2 Vasopressin Receptor Degradation by Agonist-promoted Ubiquitination

2003 • 127 citations

Rapid Internalization and Recycling of the Human Neuropeptide Y Y1 Receptor

2002 • 113 citations

Recycling of epidermal growth factor-receptor complexes in A431 cells: identification of dual pathways.

1991 • 102 citations

Direct demonstration of aquaporin-2 water channel recycling in stably transfected LLC-PK1 epithelial cells

1996 • 85 citations

A fully active nonglycosylated V2 vasopressin receptor.

1996 • 82 citations

Internalization, recycling, and redistribution of vasopressin receptors in rat hepatocytes.

1985 • 74 citations

Recycling of AQP2 occurs through a temperature- and bafilomycin-sensitivetrans-Golgi-associated compartment

2000 • 68 citations

O-Glycosylation of the V2 vasopressin receptor

1999 • 59 citations

Functional role of the NPxxY motif in internalization of the type 2 vasopressin receptor in LLC-PK1 cells

2003 • 57 citations

Internalization of vasopressin analogs in kidney and smooth muscle cells: evidence for receptor-mediated endocytosis in cells with V2 or V1 receptors.

1990 • 47 citations

Binding and internalization of a fluorescent vasopressin analogue by collecting duct cells

1988 • 43 citations

Arrestin Effects on Internalization of Vasopressin Receptors

2001 • 40 citations

Phosphorylation and Recycling Kinetics of g Protein-Coupled Receptors

1999 • 33 citations

Sorting Functions of the Individual Cytoplasmic Domains of the G Protein-Coupled Vasopressin V₂Receptor in Madin Darby Canine Kidney Epithelial Cells

2001 • 27 citations

Functional evidence for an apical V1 receptor in rabbit cortical collecting duct

1993 • 25 citations

Evidence for an acid pH in rat renal inner medulla: paired measurements with liquid ion-exchange microelectrodes on collecting ducts and vasa recta

1994 • 24 citations

Demonstration of processing and recycling of biologically active V1 vasopressin receptors in vascular smooth muscle.

1992 • 24 citations

Immunolocalization of V1 vasopressin receptors in the rat kidney using anti-receptor antibodies

1997 • 23 citations

Structural requirements for V₂ vasopressin receptor proteolytic cleavage

1999 • 18 citations

Parathyroid hormone receptor internalization is independent of protein kinase A and phospholipase C activation

2001 • 14 citations

Functional characterization of vasopressin V1 and V2 receptors in the rabbit renal cortical collecting duct.

1996 • 12 citations

Arginine Vasopressin Receptor Internalization and Recycling in Rat Renal Collecting Tubules

1994 • 8 citations

Molecular weight determination of the hepatic vasopressin receptor with a high‐affinity photoprobe

1996 • 4 citations