Nitric Oxide–Induced Motility in Aortic Smooth Muscle Cells

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

1989 • 2,183 citations

Signaling from Rho to the Actin Cytoskeleton Through Protein Kinases ROCK and LIM-kinase

1999 • 1,581 citations

Nitric oxide synthase modulates angiogenesis in response to tissue ischemia.

1998 • 1,191 citations

Protein tyrosine phosphatases in signal transduction

1997 • 766 citations

Bidirectional signaling between the cytoskeleton and integrins

1999 • 765 citations

Interplay between Rac and Rho in the control of substrate contact dynamics

1999 • 623 citations

Cyclic GMP-dependent Protein Kinase Signaling Pathway Inhibits RhoA-induced Ca2+ Sensitization of Contraction in Vascular Smooth Muscle

2000 • 599 citations

Regulation of Myosin Phosphatase by a Specific Interaction with cGMP- Dependent Protein Kinase Iα

1999 • 514 citations

Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2

1997 • 474 citations

RhoA Inactivation by p190RhoGAP Regulates Cell Spreading and Migration by Promoting Membrane Protrusion and Polarity

2001 • 431 citations

Nitric Oxide Reversibly Inhibits the Migration of Cultured Vascular Smooth Muscle Cells

1996 • 412 citations

Protein-tyrosine Phosphatase Shp-2 Regulates Cell Spreading, Migration, and Focal Adhesion

1998 • 390 citations

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras.

1994 • 389 citations

Molecular Mechanisms of Coronary Collateral Vessel Growth

1996 • 377 citations

Pericyte involvement in capillary sprouting during angiogenesis in situ

1992 • 373 citations

Role of NO in Flow-Induced Remodeling of the Rabbit Common Carotid Artery

1996 • 369 citations

A simple method for the rapid generation of recombinant adenovirus vectors

2000 • 266 citations

Site-Specific Incorporation of a Phosphotyrosine Mimetic Reveals a Role for Tyrosine Phosphorylation of SHP-2 in Cell Signaling

2001 • 261 citations

Rho and Rho Kinase Mediate Thrombin-Stimulated Vascular Smooth Muscle Cell DNA Synthesis and Migration

1999 • 260 citations

Concerted Activity of Tyrosine Phosphatase SHP-2 and Focal Adhesion Kinase in Regulation of Cell Motility

1999 • 254 citations

Ischemia-Induced Coronary Collateral Growth Is Dependent on Vascular Endothelial Growth Factor and Nitric Oxide

2000 • 238 citations

cGMP-Dependent Protein Kinase Phosphorylates and Inactivates RhoA

2001 • 218 citations

Rho kinase inhibitor HA-1077 prevents Rho-mediated myosin phosphatase inhibition in smooth muscle cells

2000 • 210 citations

Perspectives series: cell adhesion in vascular biology. Smooth muscle migration in atherosclerosis and restenosis.

1997 • 205 citations

Inducible Nitric Oxide: An Autoregulatory Feedback Inhibitor of Vascular Inflammation

1998 • 174 citations

Nitric Oxide Induces Dilation of Rat Aorta via Inhibition of Rho-Kinase Signaling

2002 • 154 citations

Apoptotic, non-apoptotic, and anti-apoptotic pathways of tumor necrosis factor signalling

1998 • 144 citations

Molecular Characterization of Specific Interactions between SHP-2 Phosphatase and JAK Tyrosine Kinases

1997 • 140 citations

Activation of Mitogen-activated Protein Kinase Pathways by Cyclic GMP and Cyclic GMP-dependent Protein Kinase in Contractile Vascular Smooth Muscle Cells

1999 • 138 citations

The protein tyrosine phosphatase Shp-2 regulates RhoA activity

2000 • 138 citations

Regulation of angiotensin II-induced JAK2 tyrosine phosphorylation: roles of SHP-1 and SHP-2

1998 • 136 citations

Overexpression of Inducible Nitric Oxide Synthase by Neointimal Smooth Muscle Cells

1998 • 133 citations

Decreased Neointimal Thickening After Arterial Wall Injury in Inducible Nitric Oxide Synthase Knockout Mice

1999 • 104 citations

Stimulation of Phosphatidylinositol-4-phosphate 5-Kinase by Rho-Kinase

2000 • 103 citations

The Phosphotyrosine Phosphatase PTP1D, but not PTP1C, Is an Essential Mediator of Fibroblast Proliferation Induced by Tyrosine Kinase and G Protein-coupled Receptors

1995 • 93 citations

Cultured aortic smooth muscle cells from newborn and adult rats show distinct cytoskeletal features

1992 • 89 citations

Nitric Oxide and C-Type Atrial Natriuretic Peptide Stimulate Primary Aortic Smooth Muscle Cell Migration via a cGMP-Dependent Mechanism

1999 • 81 citations

SHP-2 binds to Tyr763 and Tyr1009 in the PDGF β-receptor and mediates PDGF-induced activation of the Ras/MAP kinase pathway and chemotaxis

1999 • 80 citations

Nitric oxide selectively amplifies FGF-2-induced mitogenesis in primary rat aortic smooth muscle cells

1994 • 77 citations

Receptor-binding, tyrosine phosphorylation and chromosome localization of the mouse SH2-containing phosphotyrosine phosphatase Syp.

1994 • 76 citations

Effects of nitric oxide on the adhesion of human melanocytes to extracellular matrix components

1997 • 66 citations

Tyrosine Phosphatase SHP-2 Is Involved in Regulation of Platelet-derived Growth Factor-induced Migration

1999 • 64 citations

Exogenous nitric oxide inhibits mesangial cell adhesion to extracellular matrix components

1998 • 52 citations

The Kinase Inhibitor Fasudil (HA-1077) Reduces Intimal Hyperplasia through Inhibiting Migration and Enhancing Cell Loss of Vascular Smooth Muscle Cells

1999 • 52 citations

Protein-tyrosine Phosphatase 1D Modulates Its Own State of Tyrosine Phosphorylation

1995 • 47 citations

NO Attenuates Insulin Signaling and Motility in Aortic Smooth Muscle Cells via Protein Tyrosine Phosphatase 1B–Mediated Mechanism

2002 • 47 citations

NO alters cell shape and motility in aortic smooth muscle cells via protein tyrosine phosphatase 1B activation

1999 • 45 citations

Predominant expression of the src homology 2-containing tyrosine phosphatase protein SHP2 in vascular smooth muscle cells

1997 • 17 citations

Regulation of Ras and Rho small G proteins by SHP‐2

2001 • 15 citations

Requirement of protein tyrosine phosphatase SHP2 for NO-stimulated vascular smooth muscle cell motility

2001 • 14 citations

DIFFERENTIAL REGULATION BY TRANSFORMING GROWTH FACTOR‐β1 OF PLATELET‐DERIVED GROWTH FACTOR‐ STIMULATED PROLIFERATION OF VASCULAR SMOOTH MUSCLE CELLS FROM SHR AND WKY RATS

1992 • 13 citations