The Phosphotyrosine Phosphatase PTP1D, but not PTP1C, Is an Essential Mediator of Fibroblast Proliferation Induced by Tyrosine Kinase and G Protein-coupled Receptors

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation

1991 • 3,396 citations

Oncogenes and signal transduction

1991 • 2,816 citations

Growth Factors and Cancer

1991 • 2,044 citations

The MAP kinase cascade is essential for diverse signal transduction pathways

1993 • 1,091 citations

Site-directed mutagenesis of virtually any plasmid by eliminating a unique site

1992 • 1,089 citations

Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation.

1993 • 992 citations

SH2 and SH3 domains: From structure to function

1992 • 977 citations

Mutations at the murine motheaten locus are within the hematopoietic cell protein-tyrosine phosphatase (Hcph) gene

1993 • 756 citations

SH2-Containing Phosphotyrosine Phosphatase as a Target of Protein-Tyrosine Kinases

1993 • 666 citations

Activation of a Phosphotyrosine Phosphatase by Tyrosine Phosphorylation

1993 • 554 citations

A new function for a phosphotyrosine phosphatase: linking GRB2-Sos to a receptor tyrosine kinase

1994 • 477 citations

A protein-tyrosine phosphatase with sequence similarity to the SH2 domain of the protein-tyrosine kinases

1991 • 401 citations

Protein-tyrosine-phosphatase SHPTP2 couples platelet-derived growth factor receptor beta to Ras.

1994 • 389 citations

Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surface.

1986 • 374 citations

Characterization of hematopoietic intracellular protein tyrosine phosphatases: description of a phosphatase containing an SH2 domain and another enriched in proline-, glutamic acid-, serine-, and threonine-rich sequences.

1992 • 367 citations

Identification of a human src homology 2-containing protein-tyrosine-phosphatase: a putative homolog of Drosophila corkscrew.

1992 • 359 citations

Isolation of a src homology 2-containing tyrosine phosphatase.

1992 • 304 citations

Expression of catalytically inactive Syp phosphatase in 3T3 cells blocks stimulation of mitogen-activated protein kinase by insulin.

1994 • 302 citations

Association of hematopoietic cell phosphatase with c-Kit after stimulation with c-Kit ligand.

1993 • 267 citations

Syp (SH-PTP2) is a positive mediator of growth factor-stimulated mitogenic signal transduction.

1994 • 240 citations

Constitutively active mutants of MAP kinase kinase (MEK1) induce growth factor-relaxation and oncogenicity when expressed in fibroblasts.

1994 • 222 citations

A widely expressed human protein-tyrosine phosphatase containing src homology 2 domains.

1993 • 219 citations

‘Zip codes’ direct intracellular protein tyrosine phosphatases to the correct cellular ‘address’

1994 • 201 citations

Tyrosyl phosphorylation and growth factor receptor association of the human corkscrew homologue, SH-PTP2

1993 • 192 citations

Activation of Src family kinase activity by the G protein-coupled thrombin receptor in growth-responsive fibroblasts.

1994 • 186 citations

Lck-dependent tyrosyl phosphorylation of the phosphotyrosine phosphatase SH-PTP1 in murine T cells.

1994 • 159 citations

Functional expression and growth factor activation of an epitope-tagged p44 mitogen-activated protein kinase, p44mapk.

1992 • 156 citations

Transmembrane Receptors and Intracellular Pathways that Control Cell Proliferation

1992 • 151 citations

Insulin stimulates the phosphorylation of Tyr538 and the catalytic activity of PTP1C, a protein tyrosine phosphatase with Src homology-2 domains.

1994 • 129 citations

Protein tyrosine phosphatase-1C is rapidly phosphorylated in tyrosine in macrophages in response to colony stimulating factor-1.

1992 • 124 citations

Sequence specificity in recognition of the epidermal growth factor receptor by protein tyrosine phosphatase 1B.

1993 • 99 citations

Characterization of protein tyrosine phosphatase SH-PTP2. Study of phosphopeptide substrates and possible regulatory role of SH2 domains.

1994 • 92 citations

Purification and characterization of PTP2C, a widely distributed protein tyrosine phosphatase containing two SH2 domains.

1994 • 85 citations

Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C.

1994 • 78 citations

Phosphorylation and identification of a major tyrosine phosphorylation site in protein tyrosine phosphatase 1C.

1994 • 72 citations

Overexpression, purification, and characterization of SHPTP1, a Src homology 2-containing protein-tyrosine-phosphatase.

1993 • 60 citations

Phorbol ester stimulates the activity of a protein tyrosine phosphatase containing SH2 domains (PTP1C) in HL-60 leukemia cells by increasing gene expression

1993 • 55 citations

Protein-tyrosine-phosphatase 2C is phosphorylated and inhibited by 44-kDa mitogen-activated protein kinase.

1994 • 51 citations

Cloning, Functional Expression and Role in Cell Growth Regulation of a Hamster 5-HT2 Receptor Subtype

1991 • 38 citations