Cyclic GMP-dependent Protein Kinase Signaling Pathway Inhibits RhoA-induced Ca2+ Sensitization of Contraction in Vascular Smooth Muscle

Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension

1997 • 2,847 citations

Regulation of Myosin Phosphatase by Rho and Rho-Associated Kinase (Rho-Kinase)

1996 • 2,843 citations

Rho GTPases and signaling networks

1997 • 2,380 citations

Nitric oxide-generating vasodilators and 8-bromo-cyclic guanosine monophosphate inhibit mitogenesis and proliferation of cultured rat vascular smooth muscle cells.

1989 • 2,183 citations

Signal transduction and regulation in smooth muscle

1994 • 1,915 citations

Cell Biology of Atherosclerosis

1995 • 982 citations

Direct evidence for the importance of endothelium-derived nitric oxide in vascular remodeling.

1998 • 799 citations

Intracellular cyclic GMP receptor proteins

1993 • 655 citations

Protein kinase A phosphorylation of RhoA mediates the morphological and functional effects of cyclic AMP in cytotoxic lymphocytes.

1996 • 560 citations

Impairment of Endothelium-Dependent Pulmonary-Artery Relaxation in Chronic Obstructive Lung Disease

1991 • 538 citations

Regulation of Myosin Phosphatase by a Specific Interaction with cGMP- Dependent Protein Kinase Iα

1999 • 514 citations

Defective smooth muscle regulation in cGMP kinase I-deficient mice

1998 • 510 citations

The Small GTPase Rho: Cellular Functions and Signal Transduction

1996 • 404 citations

Distinct and specific functions of cGMP-dependent protein kinases

1997 • 394 citations

Reduced Endothelial Nitric Oxide Synthase Expression and Production in Human Atherosclerosis

1998 • 386 citations

A New Member of the Rho Family, Rnd1, Promotes Disassembly of Actin Filament Structures and Loss of Cell Adhesion

1998 • 349 citations

Regulation of Intracellular Ca2+ Levels in Cultured Vascular Smooth Muscle Cells

1989 • 318 citations

Role of guanine nucleotide-binding proteins--ras-family or trimeric proteins or both--in Ca2+ sensitization of smooth muscle.

1996 • 280 citations

cAMP-induced Morphological Changes Are Counteracted by the Activated RhoA Small GTPase and the Rho Kinase ROKα

1998 • 267 citations

Cyclic GMP Causes Ca2+ Desensitization in Vascular Smooth Muscle by Activating the Myosin Light Chain Phosphatase

1997 • 263 citations

Rho and Rho Kinase Mediate Thrombin-Stimulated Vascular Smooth Muscle Cell DNA Synthesis and Migration

1999 • 260 citations

Translocation of rhoA Associated with Ca2+ Sensitization of Smooth Muscle

1997 • 218 citations

The effects of the Rho‐kinase inhibitor Y‐27632 on arachidonic acid‐, GTPγS‐, and phorbol ester‐induced Ca²⁺‐sensitization of smooth muscle

1998 • 199 citations

Relation between muscarinic receptor cationic current and internal calcium in guinea‐pig jejunal smooth muscle cells.

1991 • 199 citations

Cyclic GMP-Dependent Stimulation Reverses G-Protein-Coupled Inhibition of Smooth Muscle Myosin Light Chain Phosphatase

1996 • 156 citations

Inhibition of RhoA Translocation and Calcium Sensitization by In Vivo ADP-Ribosylation with the Chimeric Toxin DC3B

1997 • 151 citations

Acceleration of Myosin Light Chain Dephosphorylation and Relaxation of Smooth Muscle by Telokin

1998 • 142 citations

Role of Rho proteins in carbachol‐induced contractions in intact and permeabilized guinea‐pig intestinal smooth muscle.

1996 • 111 citations

Simultaneous localization and quantification of relative G and F actin content: optimization of fluorescence labeling methods.

1992 • 90 citations

Mechanism of contracture on cooling of caffeine‐treated frog skeletal muscle fibres.

1988 • 89 citations

Migratory activity of human smooth muscle cells cultivated from coronary and peripheral primary and restenotic lesions removed by percutaneous atherectomy.

1992 • 72 citations

The Rho‐related protein Rnd1 inhibits Ca²⁺ sensitization of rat smooth muscle

1999 • 65 citations

Effects of the Phosphorylation of Myosin Phosphatase by Cyclic GMP-dependent Protein Kinase

1999 • 54 citations

A Research Trail Over Half a Century

1995 • 45 citations

Nitric oxide in the cardiovascular system

1999 • 19 citations

Proliferation of smooth muscle cells in acute allograft vascular rejection

1997 • 19 citations