Transcriptional Repression by Msx-1 Does Not Require Homeodomain DNA-Binding Sites

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins

1989 • 3,219 citations

Homeobox genes and axial patterning

1992 • 2,688 citations

GAL4-VP16 is an unusually potent transcriptional activator

1988 • 1,379 citations

Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

1994 • 1,271 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

The structure and function of the homeodomain

1989 • 1,007 citations

Homeo Boxes in the Study of Development

1987 • 905 citations

The T-cell transcription factor NFATp is a substrate for calcineurin and interacts with Fos and Jun

1993 • 769 citations

Isolation of coactivators associated with the TATA-binding protein that mediate transcriptional activation

1991 • 711 citations

A mutation in the homeodomain of the human MSX2 gene in a family affected with autosomal dominant craniosynostosis

1993 • 677 citations

Direct and selective binding of an acidic transcriptional activation domain to the TATA-box factor TFIID

1990 • 620 citations

Murine Developmental Control Genes

1990 • 594 citations

Factors involved in specific transcription by human RNA polymerase II: analysis by a rapid and quantitative in vitro assay.

1985 • 575 citations

A glutamine-rich hydrophobic patch in transcription factor Sp1 contacts the dTAFII110 component of the Drosophila TFIID complex and mediates transcriptional activation.

1994 • 531 citations

Wild-type p53 binds to the TATA-binding protein and represses transcription.

1992 • 527 citations

POU-domain transcription factors: pou-er-ful developmental regulators.

1991 • 461 citations

Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements

1993 • 440 citations

The Oct-1 homoeodomain directs formation of a multiprotein-DNA complex with the HSV transactivator VP16

1989 • 434 citations

Drosophila TAFII40 interacts with both a VP16 activation domain and the basal transcription factor TFIIB

1993 • 418 citations

The basics of basal transcription by RNA polymerase II

1994 • 409 citations

A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1.

1989 • 399 citations

Initiation of Transcription by RNA Polymerase II: A Multi-step Process

1993 • 390 citations

Adenovirus E1A activation domain binds the basic repeat in the TATA box transcription factor

1991 • 381 citations

Dr1, a TATA-binding protein-associated phosphoprotein and inhibitor of class II gene transcription

1992 • 379 citations

Hox-7, a mouse homeobox gene with a novel pattern of expression during embryogenesis.

1989 • 373 citations

The yeast UASG is a transcriptional enhancer in human hela cells in the presence of the GAL4 trans-activator

1988 • 362 citations

Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53

1993 • 329 citations

The nonphosphorylated form of RNA polymerase II preferentially associates with the preinitiation complex.

1991 • 319 citations

Family of proteins that interact with TFIID and regulate promoter activity

1991 • 319 citations

Activation of class II gene transcription by regulatory factors is potentiated by a novel activity

1991 • 318 citations

Human and Drosophila Homeodomain Proteins That Enhance the DNA-Binding Activity of Serum Response Factor

1992 • 314 citations

HTLV-I Tax Protein Stimulation of DNA Binding of bZIP Proteins by Enhancing Dimerization

1993 • 312 citations

DNA binding specificity of homeodomains

1991 • 300 citations

SCIP: A glial POU domain gene regulated by cyclic AMP

1989 • 293 citations

Functional domains of the Drosophila Engrailed protein.

1993 • 280 citations

Cloning of a human gene encoding the general transcription initiation factor IIB

1991 • 274 citations

Species-specific interaction of the glutamine-rich activation domains of Sp1 with the TATA box-binding protein.

1994 • 266 citations

extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1

1993 • 264 citations

Regulatory crosstalk at composite response elements

1991 • 261 citations

Promoter targeting by adenovirus E1a through interaction with different cellular DNA-binding domains

1994 • 256 citations

The homeobox gene Hox 7.1 has specific regional and temporal expression patterns during early murine craniofacial embryogenesis, especially tooth development in vivo and in vitro

1991 • 256 citations

Factors involved in specific transcription by mammalian RNA polymerase II: role of transcription factors IIA, IID, and IIB during formation of a transcription-competent complex.

1990 • 255 citations

Functional dissection of ultrabithorax proteins in D. melanogaster

1990 • 255 citations

The p53 Activation Domain Binds the TATA Box-Binding Polypeptide in Holo-TFIID, and a Neighboring p53 Domain Inhibits Transcription

1993 • 246 citations

Expression and purification of the leucine zipper and DNA-binding domains of Fos and Jun: both Fos and Jun contact DNA directly.

1990 • 245 citations

Expression and Activity of the POU Transcription Factor SCIP

1990 • 244 citations

Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain.

1993 • 241 citations

Regulation of cytomegalovirus gene expression: alpha and beta promoters are trans activated by viral functions in permissive human fibroblasts

1985 • 229 citations

Drosophila Krüppel protein is a transcriptional represser

1990 • 228 citations

EGR3, a novel member of the Egr family of genes encoding immediate-early transcription factors.

1991 • 218 citations

The Msh-like homeobox genes define domains in the developing vertebrate eye

1991 • 217 citations

Cooperative Interactions Between the Caenorhabditis elegans Homeoproteins UNC-86 and MEC-3

1993 • 215 citations

Oncogenic conversion by regulatory changes in transcription factors

1991 • 215 citations

GAL4 fusion vectors for expression in yeast or mammalian cells

1992 • 213 citations

Expression of Hox-7.1 in myoblasts inhibits terminal differentiation and induces cell transformation

1992 • 209 citations

Structure and functional properties of human general transcription factor IIE

1991 • 194 citations

The specificities of sex combs reduced and Antennapedia are defined by a distinct portion of each protein that includes the homeodomain

1990 • 189 citations

Nucleotides flanking a conserved TAAT core dictate the DNA binding specificity of three murine homeodomain proteins.

1993 • 182 citations

Transcriptional regulation by Fos and Jun in vitro: interaction among multiple activator and regulatory domains.

1991 • 175 citations

Association between proto-oncoprotein Rel and TATA-binding protein mediates transcriptional activation by NF-κB

1993 • 168 citations

The apical ectodermal ridge regulates Hox-7 and Hox-8 gene expression in developing chick limb buds.

1991 • 152 citations

Ectopic expression and function of the Antp and Scr homeotic genes: the N terminus of the homeodomain is critical to functional specificity

1993 • 142 citations

A homeodomain substitution changes the regulatory specificity of the Deformed protein in drosophila embryos

1989 • 142 citations

Factors Involved in Specific Transcription by Mammalian RNA Polymerase II: Purification and Analysis of Transcription Factor ILA and Identification of Transcription Factor IIJ

1992 • 136 citations

Mapping functional specificity in the Dfd and Ubx homeo domains.

1992 • 134 citations

Factors involved in specific transcription by mammalian RNA polymerase II. Purification and subunit composition of transcription factor IIF.

1990 • 129 citations

Specificity of HOX protein function depends on DNA-protein and protein-protein interactions, both mediated by the homeo domain.

1994 • 126 citations

Cloning and evolutionary analysis of msh-like homeobox genes from mouse, zebrafish and ascidian

1991 • 122 citations

Chicken homeobox gene Msx-1: structure, expression in limb buds and effect of retinoic acid

1991 • 120 citations

Recognition of the surface of a homeo domain protein.

1992 • 115 citations

Characterization of the zinc finger protein encoded by the WT1 Wilms' tumor locus.

1991 • 114 citations

Activation and repression of transcription by the gap proteins hunchback and Krüppel in cultured Drosophila cells.

1991 • 107 citations

A structure-function analysis of transcriptional repression mediated by the WT1, Wilms' tumor suppressor protein.

1993 • 107 citations

Functional Interaction of the v-Rel and c-Rel Oncoproteins with the TATA-Binding Protein and Association with Transcription Factor IIB

1993 • 102 citations

Molecular aspects of regeneration in developing vertebrate limbs

1992 • 99 citations

Human beta-polymerase gene. Structure of the 5′-flanking region and active promoter.

1988 • 96 citations

Homeodomain-independent activity of the fushi tarazu polypeptide in Drosophila embryos

1992 • 96 citations

Repression of the myelin P0 gene by the POU transcription factor SCIP

1993 • 95 citations

Altered expression of the chicken homeobox-containing genes GHox-7 and GHox-8 in the limb buds of limbless mutant chick embryos

1991 • 91 citations

Conservation of a functional hierarchy between mammalian and insect Hox/HOM genes.

1994 • 78 citations

Hox proteins have different affinities for a consensus DNA site that correlate with the positions of their genes on the hox cluster.

1994 • 77 citations

Apical ridge dependent and independent mesodermal domains of GHox-7 and GHox-8 expression in chick limb buds

1992 • 66 citations

Multiple sites of HOX‐7 expression during mouse embryogenesis: Comparison with retinoic acid receptor mRNA localization

1992 • 58 citations

Mammalian homeobox genes in normal development and neoplasia.

1992 • 57 citations

Differential DNA binding properties of three human homeodomain proteins

1992 • 54 citations

Design of a "minimAl" homeodomain: the N-terminal arm modulates DNA binding affinity and stabilizes homeodomain structure.

1994 • 46 citations

Synergistic activation of transcription is mediated by the N-terminal domain of Drosophila fushi tarazu homeoprotein and can occur without DNA binding by the protein.

1993 • 42 citations

Cell-specific action and mutable structure of a transcription factor effector domain.

1993 • 31 citations