Activation and repression of transcription by the gap proteins hunchback and Krüppel in cultured Drosophila cells.

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

How eukaryotic transcriptional activators work

1988 • 1,924 citations

Antitumor promotion and antiinflammation: Down-modulation of AP-1 (Fos/Jun) activity by glucocorticoid hormone

1990 • 1,605 citations

Transcriptional interference between c-Jun and the glucocorticoid receptor: Mutual inhibition of DNA binding due to direct protein-protein interaction

1990 • 1,583 citations

Functional antagonism between oncoprotein c-Jun and the glucocorticoid receptor

1990 • 1,272 citations

Cell lines derived from late embryonic stages of Drosophila melanogaster

1972 • 1,215 citations

The molecular genetics of embryonic pattern formation in Drosophila

1988 • 1,048 citations

Mechanism of transcriptional activation by Sp1: Evidence for coactivators

1990 • 1,029 citations

The molecular basis for metameric pattern in the Drosophila embryo

1987 • 1,028 citations

The bicoid protein determines position in the Drosophila embryo in a concentration-dependent manner

1988 • 1,022 citations

A gradient of bicoid protein in Drosophila embryos

1988 • 1,015 citations

The bicoid protein is a positive regulator of hunchback transcription in the early Drosophila embryo

1989 • 672 citations

The gradient morphogen bicoid is a concentration-dependent transcriptional activator

1989 • 655 citations

Multiple sequence motifs are involved in SV40 enhancer function.

1986 • 511 citations

Positive and negative regulation of gene transcription by a retinoic acid-thyroid hormone receptor heterodimer

1989 • 508 citations

The sequence specificity of homeodomain-DNA interaction

1988 • 501 citations

Characterization and localization of the even-skipped protein of Drosophila.

1987 • 496 citations

Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene network

1986 • 496 citations

Divergent homeo box proteins recognize similar DNA sequences in Drosophila

1988 • 491 citations

Transcriptional repression of eukaryotic promoters

1989 • 481 citations

The engrailed locus of drosophila: In situ localization of transcripts reveals compartment-specific expression

1985 • 456 citations

Determination of spatial domains of zygotic gene expression in the Drosophila embryo by the affinity of binding sites for the bicoid morphogen

1989 • 432 citations

Structural homology of the product of the Drosophila Krüppel gene with Xenopus transcription factor IIIA

1986 • 406 citations

Organization of anterior pattern in the Drosophila embryo by the maternal gene bicoid

1986 • 386 citations

Finger protein of novel structure encoded by hunchback, a second member of the gap class of Drosophila segmentation genes

1987 • 370 citations

Molecular and Genetic Organization of The Antennapedia Gene Complex of Drosophila melanogaster

1990 • 360 citations

Synergistic activation and repression of transcription by Drosophila homeobox proteins

1989 • 353 citations

The SV40 enhancer is composed of multiple functional elements that can compensate for one another

1986 • 293 citations

Transcriptional activation and repression by Ultrabithorax proteins in cultured Drosophila cells

1989 • 291 citations

Complementary patterns of even-skipped and fushi tarazu expression involve their differential regulation by a common set of segmentation genes in Drosophila.

1987 • 276 citations

Early and late periodic patterns of even skipped expression are controlled by distinct regulatory elements that respond to different spatial cues

1989 • 273 citations

Sequence-specific DNA-binding activities of the gap proteins encoded by hunchback and Krüppel in Drosophila

1989 • 270 citations

Autoregulatory and gap gene response elements of the even-skipped promoter of Drosophila.

1989 • 254 citations

Zygotically active genes that affect the spatial expression of the fushi tarazu segmentation gene during early Drosophila embryogenesis

1986 • 242 citations

Drosophila Krüppel protein is a transcriptional represser

1990 • 228 citations

Differing strategies for organizing anterior and posterior body pattern in Drosophila embryos

1989 • 222 citations

Evidence for interaction of different eukaryotic transcriptional activators with distinct cellular targets

1990 • 221 citations

Establishment and refinement of segmental pattern in the Drosophila embryo: spatial control of engrailed expression by pair-rule genes.

1987 • 220 citations

Activation and repression of transcription by homoeodomain-containing proteins that bind a common site

1988 • 217 citations

Abdominal segmentation of the Drosophila embryo requires a hormone receptor-like protein encoded by the gap gene knirps

1988 • 217 citations

The correct activation of Antennapedia and bithorax complex genes requires the fushi tarazu gene

1986 • 201 citations

Regulation of segment polarity genes in the Drosophila blastoderm by fushi tarazu and even skipped

1988 • 194 citations

Accurate measurements of dynamics and reproducibility in small genetic networks

2013 • 174 citations

Cross-regulatory interactions among the gap genes of Drosophila

1986 • 168 citations

Spatial Programming of Gene Expression in Early Drosophila Embryogenesis

1986 • 157 citations

Gap genes define the limits of antennapedia and bithorax gene expression during early development in Drosophila.

1988 • 151 citations

The products of the Drosophila gap genes hunchback and Krüppel bind to the hunchback promoters

1989 • 146 citations

A purified Drosophila homeodomain protein represses transcription in vitro

1989 • 142 citations

Krüppel requirement for knirps enhancement reflects overlapping gap gene activities in the Drosophila embryo

1989 • 140 citations

Gradients of Krüppel and knirps gene products direct pair-rule gene stripe patterning in the posterior region of the drosophila embryo

1990 • 137 citations

Transcriptional activation by the Antennapedia and fushi tarazu proteins in cultured Drosophila cells

1989 • 129 citations

Molecular characterization of the zerknüllt region of the Antennapedia gene complex in Drosophila.

1987 • 119 citations

Correlative changes in homoeotic and segmentation gene expression in Krüppel mutant embryos of Drosophila

1986 • 111 citations

Disruption of a putative Cys–zinc interaction eliminates the biological activity of the Krüppel finger protein

1988 • 84 citations

Zebra patterns in fly embryos: Activation of stripes or repression of interstripes?

1990 • 80 citations

Binding site-dependent direct activation and repression of in vitro transcription by Drosophila homeodomain proteins

1990 • 78 citations

Patterns of engrailed protein in early Drosophila embryos

1989 • 70 citations

Analysis of maternal effect mutant combinations elucidates regulation and function of the overlap of hunchback and Krüppel gene expression in the Drosophila blastoderm embryo

1989 • 68 citations

The zygotic control of Drosophila pair-rule gene expression: II. Spatial repression by gap and pair-rule gene products

1989 • 55 citations

Evolutionary Conservation of Homeodomain-Binding Sites and Other Sequences Upstream and within the Major Transcription Unit of the Drosophila Segmentation Gene engrailed

1989 • 54 citations

The Drosophila fushi tarazu polypeptide is a DNA-binding transcriptional activator in yeast cells

1989 • 50 citations