Vertebrate Sprouty genes are induced by FGF signaling and can cause chondrodysplasia when overexpressed

Cbfa1, a Candidate Gene for Cleidocranial Dysplasia Syndrome, Is Essential for Osteoblast Differentiation and Bone Development

1997 • 2,784 citations

Regulation of Rate of Cartilage Differentiation by Indian Hedgehog and PTH-Related Protein

1996 • 1,952 citations

A series of normal stages in the development of the chick embryo

1992 • 1,860 citations

Structural and Functional Diversity in the FGf Receptor Multigene Family

1992 • 1,262 citations

Fgf10 is essential for limb and lung formation

1999 • 1,204 citations

The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo

1995 • 1,175 citations

The Fgf Family of Growth Factors and Oncogenes

1992 • 1,164 citations

The proximo‐distal sequence of origin of the parts of the chick wing and the role of the ectoderm

1948 • 1,101 citations

Fibroblast Growth Factor Receptor 3 Is a Negative Regulator of Bone Growth

1996 • 1,062 citations

An Fgf8 mutant allelic series generated by Cre- and Flp-mediated recombination

1998 • 1,048 citations

Connective Tissue and Its Heritable Disorders

2002 • 930 citations

Fgf-10 is required for both limb and lung development and exhibits striking functional similarity to Drosophila branchless

1998 • 869 citations

Skeletal overgrowth and deafness in mice lacking fibroblast growth factor receptor 3

1996 • 867 citations

fgfr-1 is required for embryonic growth and mesodermal patterning during mouse gastrulation.

1994 • 784 citations

Murine FGFR-1 is required for early postimplantation growth and axial organization.

1994 • 748 citations

sprouty Encodes a Novel Antagonist of FGF Signaling that Patterns Apical Branching of the Drosophila Airways

1998 • 745 citations

Requirement of FGF-4 for Postimplantation Mouse Development

1995 • 743 citations

Midbrain development induced by FGF8 in the chick embryo

1996 • 734 citations

A Physical Map of 30,000 Human Genes

1998 • 723 citations

Positional Information in Chick Limb Morphogenesis

1973 • 718 citations

Fgf-4 expression during gastrulation, myogenesis, limb and tooth development in the mouse

1992 • 676 citations

FGF-4 replaces the apical ectodermal ridge and directs outgrowth and patterning of the limb

1993 • 660 citations

The roles of FGFs in the early development of vertebrate limbs

1998 • 659 citations

The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryos

1995 • 648 citations

Targeted disruption of Fgf8 causes failure of cell migration in the gastrulating mouse embryo

1999 • 644 citations

branchless Encodes a Drosophila FGF Homolog That Controls Tracheal Cell Migration and the Pattern of Branching

1996 • 631 citations

Targeted disruption of fibroblast growth factor (FGF) receptor 2 suggests a role for FGF signaling in pregastrulation mammalian development

1998 • 618 citations

Antagonistic Interactions between FGF and BMP Signaling Pathways: A Mechanism for Positioning the Sites of Tooth Formation

1997 • 604 citations

Roles for FGF8 in the Induction, Initiation, and Maintenance of Chick Limb Development

1996 • 588 citations

Maps from two interspecific backcross DNA panels available as a community genetic mapping resource

1994 • 587 citations

Fibroblast growth factors induce additional limb development from the flank of chick embryos

1995 • 578 citations

Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction

1998 • 555 citations

Two FGF receptor genes are differentially expressed in epithelial and mesenchymal tissues during limb formation and organogenesis in the mouse

1992 • 552 citations

Distinct roles of type I bone morphogenetic protein receptors in the formation and differentiation of cartilage

1997 • 504 citations

Fibroblast Growth Factors as Multifunctional Signaling Factors

1998 • 489 citations

FGFR-3 and FGFR-4 function cooperatively to direct alveogenesis in the murine lung

1998 • 483 citations

The Drosophila Gene hid Is a Direct Molecular Target of Ras-Dependent Survival Signaling

1998 • 477 citations

FGF-2: Apical Ectodermal Ridge Growth Signal for Chick Limb Development

1994 • 470 citations

Sprouty, an Intracellular Inhibitor of Ras Signaling

1999 • 462 citations

Molecular mechanisms of angiogenesis: fibroblast growth factor signal transduction

1995 • 461 citations

Repression of hedgehog signaling and BMP4 expression in growth plate cartilage by fibroblast growth factor receptor 3

1998 • 402 citations

A quantitative analysis of the effect of excision of the AER from the chick limb-bud

1974 • 376 citations

Chapter 10 Manipulating Gene Expression with Replication--Competent Retroviruses

1996 • 344 citations

Involvement of FGF8 in initiation, outgrowth and patterning of the vertebrate limb

1996 • 335 citations

Chimeric analysis of fibroblast growth factor receptor-1 (Fgfr1) function: a role for FGFR1 in morphogenetic movement through the primitive streak

1997 • 329 citations

FGFR activation in skeletal disorders: Too much of a good thing

1997 • 319 citations

Involvement of FGF-8 in initiation, outgrowth and patterning of the vertebrate limb

1996 • 314 citations

Abnormal bone growth and selective translational regulation in basic fibroblast growth factor (FGF-2) transgenic mice.

1995 • 304 citations

A novel pathway for secretory proteins?

1990 • 292 citations

Expression and function of FGFs-4, -8, and -9 suggest functional redundancy and repetitive use as epithelial signals during tooth morphogenesis

1998 • 272 citations

Sprouty: a common antagonist of FGF and EGF signaling pathways in Drosophila

1999 • 254 citations

Of Worms and Men: An Evolutionary Perspective on the Fibroblast Growth Factor (FGF) and FGF Receptor Families

1997 • 211 citations

Functions of fibroblast growth factors in vertebrate development

1996 • 208 citations

Cloning and expression pattern of a mouse homologue of Drosophila sprouty in the mouse embryo

1999 • 187 citations

Fibroblast growth factor receptors: lessons from the genes

1998 • 175 citations

Structure and Expression of the mRNA Encoding a Novel Fibroblast Growth Factor, FGF-18

1998 • 150 citations

Targeted Gene Misexpression in Chick Limb Buds Using Avian Replication-Competent Retroviruses

1998 • 148 citations

A new role for Notch and Delta in cell fate decisions: patterning the feather array

1998 • 124 citations

Genetics of skeletogenesis

1998 • 93 citations

Understanding cell migration guidance: lessons from sex myoblast migration in C. elegans

1998 • 32 citations

Morphogenesis: FGF branches out

1997 • 22 citations

Transcriptional analysis of the candidate region for incontinentia pigmenti (IP2) in Xq28.

1996 • 22 citations