Macrophage Role in the Anti-Prostate Cancer Response to One Class of Antiangiogenic Agents

Vaccination with irradiated tumor cells engineered to secrete murine granulocyte-macrophage colony-stimulating factor stimulates potent, specific, and long-lasting anti-tumor immunity.

1993 • 2,828 citations

Thalidomide is an inhibitor of angiogenesis.

1994 • 2,460 citations

Clinical Cancer Research

1941 • 1,358 citations

Macrophages and angiogenesis

1994 • 1,123 citations

Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation.

1993 • 1,058 citations

Regulators of Angiogenesis

1991 • 959 citations

Genistein, a dietary-derived inhibitor of in vitro angiogenesis.

1993 • 777 citations

Human interferon-inducible protein 10 is a potent inhibitor of angiogenesis in vivo.

1995 • 710 citations

Programmed cell death during regression of PC-82 human prostate cancer following androgen ablation.

1990 • 485 citations

Vascular Endothelial Cell Growth Factor Promotes Tyrosine Phosphorylation of Mediators of Signal Transduction That Contain SH2 Domains

1995 • 480 citations

Effects of Thalidomide and Related Metabolites in a Mouse Corneal Model of Neovascularization

1997 • 447 citations

Establishment and characterization of seven dunning rat prostatic cancer cell lines and their use in developing methods for predicting metastatic abilities of prostatic cancers

1986 • 412 citations

The Molecular Basis of Cancer

1985 • 389 citations

Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages.

1984 • 366 citations

Urokinase-type plasminogen activator is induced in migrating capillary endothelial cells.

1987 • 286 citations

Androgens regulate vascular endothelial growth factor content in normal and malignant prostatic tissue.

1997 • 215 citations

Prognostic value of urokinase-type plasminogen activator (uPA) and plasminogen activator inhibitors PAI-1 and PAI-2 in breast carcinomas

1994 • 159 citations

Lipopolysaccharide‐induced cytokine production in human monocytes: Role of tyrosine phosphorylation in transmembrane signal transduction

1994 • 158 citations

IL-12 regulates VEGF and MMPs in a murine breast cancer model

1998 • 138 citations

Alterations of the p53 tumor suppressor gene and its association with activation of the c-K-ras-2 protooncogene in premalignant and malignant lesions of the human uterine endometrium.

1993 • 131 citations

Inhibition of cancer cell urokinase plasminogen activator by its specific inhibitor PAI-2 and subsequent effects on extracellular matrix degradation.

1990 • 112 citations

Plasminogen activator inhibitor-2: prognostic relevance in 1012 patients with primary breast cancer.

1995 • 106 citations

Antiangiogenic effects of the quinoline-3-carboxamide linomide.

1993 • 104 citations

Potentiation of the antiangiogenic ability of linomide by androgen ablation involves down-regulation of vascular endothelial growth factor in human androgen-responsive prostatic cancers.

1997 • 102 citations

Linomide inhibits angiogenesis, growth, metastasis, and macrophage infiltration within rat prostatic cancers.

1995 • 99 citations

Plasminogen activator system in human breast cancer

1992 • 78 citations

Antiangiogenic treatment with linomide as chemoprevention for prostate, seminal vesicle, and breast carcinogenesis in rodents.

1996 • 57 citations

Human prostatic cancer cells are sensitive to programmed (apoptotic) death induced by the antiangiogenic agent linomide.

1995 • 56 citations

The antitumor effects of the quinoline-3-carboxamide linomide on Dunning R-3327 rat prostatic cancers.

1992 • 56 citations

Urokinase Plasminogen Activator Induces Angiogenesis and Tumor Vessel Invasion in Breast Cancer

1995 • 44 citations

Inhibition of tumor angiogenesis and the therapeutic ability of linomide against rat prostatic cancers

1995 • 40 citations

Macrophage colony-stimulating factor and granulocyte-macrophage colony- stimulating factor stimulate the synthesis of plasminogen-activator inhibitors by human monocytes

1993 • 37 citations

Anti-Angiogenic Treatment with Linomide as Adjuvant to Surgical Castration in Experimental Prostate Cancer

1997 • 27 citations

The effect of linomide on the migration and the proliferation of capillary endothelial cells elicited by vascular endothelial growth factor

1996 • 20 citations

Studies on tumor induced angiogenesis

1992 • 17 citations

The antiangiogenic agent linomide inhibits tumor necrosis factor-α secretion via inhibition of its synthesis

1996 • 16 citations

Production of plasminogen activator inhibitor type-2 in human peripheral blood monocytes upregulated in vitro by the quinoline-3-carboxamide, Linomide

1996 • 6 citations

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