Effects of Thalidomide and Related Metabolites in a Mouse Corneal Model of Neovascularization

Thalidomide is an inhibitor of angiogenesis.

1994 • 2,460 citations

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

1989 • 2,267 citations

Definition of Two Angiogenic Pathways by Distinct α _v Integrins

1995 • 1,333 citations

Thalidomide selectively inhibits tumor necrosis factor alpha production by stimulated human monocytes.

1991 • 1,209 citations

THALIDOMIDE AND CONGENITAL ABNORMALITIES

1961 • 1,089 citations

Thalidomide exerts its inhibitory action on tumor necrosis factor alpha by enhancing mRNA degradation.

1993 • 1,058 citations

Heparin Affinity: Purification of a Tumor-Derived Capillary Endothelial Cell Growth Factor

1984 • 937 citations

Tumor necrosis factor type alpha, a potent inhibitor of endothelial cell growth in vitro, is angiogenic in vivo.

1987 • 718 citations

A model of angiogenesis in the mouse cornea.

1996 • 411 citations

Thalidomide for the Treatment of Chronic Graft-versus-Host Disease

1992 • 394 citations

THALIDOMIDE AND CONGENITAL ABNORMALITIES

1962 • 355 citations

THALIDOMIDE AND CONGENITAL ABNORMALITIES

1962 • 326 citations

Chromatographische Racemattrennung

1980 • 224 citations

Toxicity and Teratogenicity of Optical Isomers of Thalidomide

1967 • 186 citations

Treatment of cutaneous and pulmonary sarcoidosis with thalidomide

1995 • 167 citations

THE METABOLISM OF THALIDOMIDE: THE SPONTANEOUS HYDROLYSIS OF THALIDOMIDE IN SOLUTION

1965 • 148 citations

Clinical experience with thalidomide in the management of severe oral and genital ulceration in conditions such as Behcet's disease: use of neurophysiological studies to detect thalidomide neuropathy.

1994 • 145 citations

The Treatment of Lepra Reaction In Lepromatous Leprosy

1980 • 130 citations

Differential effects of pentoxifylline on the production of tumour necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) by monocytes and T cells.

1992 • 126 citations

Chirality in antirheumatic drugs

1991 • 109 citations

THE METABOLISM OF THALIDOMIDE: THE FATE OF THALIDOMIDE AND SOME OF ITS HYDROLYSIS PRODUCTS IN VARIOUS SPECIES

1965 • 109 citations

A comparison of the teratogenic activity of thalidomide in rabbits and rats.

1968 • 103 citations

(S)-Form of .ALPHA.-Methyl-N(.ALPHA.)-phthalimidoglutarimide, but Not Its (R)-Form, Enhanced Phorbol Ester-Induced Tumor Necrosis Factor-.ALPHA. Production by Human Leukemia Cell HL-60: Implication of Optical Resolution of Thalidomidal Effects.

1994 • 79 citations

Down-regulation of adhesion receptors on cells of primate embryos as a probable mechanism of the teratogenic action of thalidomide

1995 • 74 citations

Evaluation of the teratogenicity of drugs

1964 • 72 citations

Further Observation with Thalidomide in Lepra Reactions

1965 • 64 citations

Non‐confirmation of thalidomide induced teratogenesis in rats and mice

1977 • 57 citations

The enantiomers of the teratogenic thalidomide analogue EM 12

1988 • 53 citations

Disposition of thalidomide in rabbits and rats.

1968 • 49 citations

The teratogenic activity of α thalidomide analogue, EM12, in rabbits, rats, and monkeys

1972 • 48 citations

Effect of Thalidomide on the Graft versus Host Reaction

1966 • 48 citations

Embryotoxic effects of thalidomide derivatives in the non‐human primate Callithrix jacchus. IV. Teratogenicity of μg/kg doses of the EM12 enantiomers

1994 • 40 citations

Immunohistochemical detection of bFGF and TNF-alpha in the course of inflammatory angiogenesis in the mouse cornea.

1990 • 39 citations

The enantiomers of the teratogenic thalidomide analogue EM 12

1989 • 31 citations

The fate of[14C]thalidomide in the pregnant rabbit

1967 • 23 citations

Effects of maternal thalidomide treatment on pregnancy, fetal development, and mortality of the offspring in random-bred mice.

1967 • 18 citations

The effect of thalidomide and supidimide on endotoxin-induced uveitis in rats

1995 • 14 citations

Teratogenic activity of a hydrolytic thalidomide metabolite in mice

1982 • 10 citations

The thalidomide analog, EM 12, enhances 1,2-dimethylhydrazine-induction of rat colon adenocarcinomas

1991 • 1 citations