Regulators of Angiogenesis

Epidermal Growth Factor

1979 • 2,964 citations

Pituitary follicular cells secrete a novel heparin-binding growth factor specific for vascular endothelial cells

1989 • 2,267 citations

The Human Hematopoietic Colony-Stimulating Factors

1987 • 1,728 citations

Cachectin and tumour necrosis factor as two sides of the same biological coin

1986 • 1,659 citations

Tumor vascular permeability factor stimulates endothelial cell growth and angiogenesis.

1989 • 1,282 citations

A tumor suppressor-dependent inhibitor of angiogenesis is immunologically and functionally indistinguishable from a fragment of thrombospondin.

1990 • 1,062 citations

Nucleotide Sequence of a Bovine Clone Encoding the Angiogenic Protein, Basic Fibroblast Growth Factor

1986 • 1,032 citations

Human KGF is FGF-Related with Properties of a Paracrine Effector of Epithelial Cell Growth

1989 • 989 citations

Heparin Affinity: Purification of a Tumor-Derived Capillary Endothelial Cell Growth Factor

1984 • 937 citations

Isolation and characterization of angiogenin, an angiogenic protein from human carcinoma cells

1985 • 911 citations

Transforming growth factors produced by certain human tumor cells: polypeptides that interact with epidermal growth factor receptors.

1980 • 892 citations

Transforming Growth Factor-α: a More Potent Angiogenic Mediator than Epidermal Growth Factor

1986 • 856 citations

Peptide growth factors are multifunctional

1988 • 835 citations

Inhibition of Angiogenesis by Recombinant Human Platelet Factor-4 and Related Peptides

1990 • 710 citations

Primary structure of bovine pituitary basic fibroblast growth factor (FGF) and comparison with the amino-terminal sequence of bovine brain acidic FGF.

1985 • 710 citations

Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1.

1986 • 709 citations

Human Endothelial Cell Growth Factor: Cloning, Nucleotide Sequence, and Chromosome Localization

1986 • 679 citations

Isolation of brain fibroblast growth factor by heparin-Sepharose affinity chromatography: identity with pituitary fibroblast growth factor.

1984 • 624 citations

Inhibition of capillary endothelial cell growth by pericytes and smooth muscle cells.

1987 • 607 citations

Basic fibroblast growth factor binds to subendothelial extracellular matrix and is released by heparitinase and heparin-like molecules

1989 • 597 citations

Isolation and characterization of a vascular endothelial cell mitogen produced by pituitary-derived folliculo stellate cells.

1989 • 568 citations

Type beta transforming growth factor in human platelets: release during platelet degranulation and action on vascular smooth muscle cells.

1986 • 542 citations

Human basic fibroblast growth factor gene encodes four polypeptides: three initiate translation from non-AUG codons.

1989 • 527 citations

An oncogene isolated by transfection of Kaposi's sarcoma DNA encodes a growth factor that is a member of the FGF family

1987 • 525 citations

Purification and characterization of two cartilage-inducing factors from bovine demineralized bone.

1985 • 503 citations

Regulation of the activity of a new inhibitor of angiogenesis by a cancer suppressor gene

1989 • 475 citations

Amino acid and cDNA sequences of a vascular endothelial cell mitogen that is homologous to platelet-derived growth factor.

1990 • 368 citations

Inhibition of tumor angiogenesis mediated by cartilage.

1975 • 361 citations

Amino acid sequence of human tumor derived angiogenin

1985 • 357 citations

Brain-Derived Acidic Fibroblast Growth Factor: Complete Amino Acid Sequence and Homologies

1985 • 335 citations

Inhibitory action of transforming growth factor beta on endothelial cells.

1987 • 324 citations

Inhibition of endothelial cell proliferation by type β-transforming growth factor: Interactions with acidic and basic fibroblast growth factors

1986 • 312 citations

Isolations of a Cartilage Factor That Inhibits Tumor Neovascularization

1976 • 308 citations

Vascular endothelial growth factor: A new member of the platelet-derived growth factor gene family

1989 • 308 citations

Human endothelial cells are chemotactic to endothelial cell growth factor and heparin.

1985 • 282 citations

Site-Directed Neovessel Formation in Vivo

1988 • 278 citations

Increased capillary endothelial cell protease activity in response to angiogenic stimuli in vitro.

1983 • 261 citations

Inhibition of angiogenesis through modulation of collagen metabolism.

1988 • 240 citations

Aortic endothelial cells synthesize basic fibroblast growth factor which remains cell associated and platelet‐derived growth factor‐like protein which is secreted

1987 • 229 citations

Accelerated wound repair, cell proliferation, and collagen accumulation are produced by a cartilage-derived growth factor.

1985 • 221 citations

Heparin affinity of anionic and cationic capillary endothelial cell growth factors: analysis of hypothalamus-derived growth factors and fibroblast growth factors.

1985 • 214 citations

Angiogenesis is stimulated by a tumor‐derived endothelial cell growth factor

1985 • 203 citations

Comparison of the biological actions of TGF beta‐1 and TGF beta‐2: Differential activity in endothelial cells

1988 • 195 citations

Growth Inhibition of Murine Melanoma and Human Colon Carcinoma by Recombinant Human Platelet Factor 4

1990 • 190 citations

Isolation of angiogenin from normal human plasma

1987 • 187 citations

Prolonged tumor dormancy by prevention of neovascularization in the vitreous.

1976 • 176 citations

Control of tumor growth in animals by infusion of an angiogenesis inhibitor.

1980 • 154 citations

Specific binding of angiogenin to calf pulmonary artery endothelial cells.

1989 • 134 citations

1-Butyryl-Glycerol: A novel angiogenesis factor secreted by differentiating adipocytes

1990 • 124 citations

Protamine sulfate inhibits mitogenic activities of the extracellular matrix and fibroblast growth factor, but potentiates that of epidermal growth factor

1987 • 86 citations

Antitumor effect of tumor necrosis factor against various primarily cultured human cancer cells.

1985 • 77 citations

An Endothelial Cell Growth Factor from the Mouse Neuroblastoma Cell Line NB41

1989 • 71 citations

Protamine inhibits capillary formation in growing rat hearts.

1985 • 65 citations

Purification and partial amino acid sequence of a bovine cartilage-derived collagenase inhibitor.

1986 • 61 citations

Production of platelet-derived endothelial cell growth factor by normal and transformed human cells in culture.

1989 • 60 citations

Inhibitor of Vascular Endothelial Cell Growth in the Lens

1984 • 53 citations

Purification of 18- and 22-kDa Forms of Basic Fibroblast Growth Factor from Rat Cells Transformed by the ras Oncogene

1989 • 51 citations

Purified monocyte-derived angiogenic substance (angiotropin) induces controlled angiogenesis associated with regulated tissue proliferation in rabbit skin.

1988 • 50 citations

Heparin-Mediated Release of Fibroblast Growth Factor-Like Activity into the Circulation of Rabbits

1990 • 40 citations

Prevention of carcinomatosis and bloody malignant ascites in the rat by an inhibitor of angiogenesis

1984 • 38 citations

Proviral insertions within the int-2 gene can generate multiple anomalous transcripts but leave the protein-coding domain intact

1990 • 33 citations

In Vivo Studies on the Binding of Heparin and Its Fractions with Platelet Factor 4

1985 • 29 citations

Inhibition of tumour‐induced angiogenesis by systemically administered protamine sulphate

1984 • 25 citations

Inhibition of vascularization in rabbit corneas by heparin: cortisone pellets.

1986 • 19 citations

Inhibition of tumor angiogenesis by hexuronyl hexosaminoglycan sulfate

1986 • 18 citations