The Drosophila STE20-like kinase Misshapen is required downstream of the Frizzled receptor in planar polarity signaling

Specificity of receptor tyrosine kinase signaling: Transient versus sustained extracellular signal-regulated kinase activation

1995 • 4,589 citations

Analysis of genetic mosaics in developing and adult Drosophila tissues

1993 • 2,029 citations

The small GTP-binding proteins Rac1 and Cdc42regulate the activity of the JNK/SAPK signaling pathway

1995 • 1,653 citations

Selective activation of the JNK signaling cascadeand c-Jun transcriptional activity by the small GTPases Rac and Cdc42Hs

1995 • 1,499 citations

Regulation of transcription by MAP kinase cascades

1996 • 1,330 citations

Sounding the Alarm: Protein Kinase Cascades Activated by Stress and Inflammation

1996 • 1,099 citations

MAP kinase pathways in yeast: For mating and more

1995 • 1,009 citations

MAP kinase kinase kinase, MAP kinase kinase and MAP kinase

1994 • 1,005 citations

The Pathways Connecting G Protein-coupled Receptors to the Nucleus through Divergent Mitogen-activated Protein Kinase Cascades

1998 • 819 citations

Dishevelled Activates JNK and Discriminates between JNK Pathways in Planar Polarity and wingless Signaling

1998 • 774 citations

Differential recruitment of Dishevelled provides signaling specificity in the planar cell polarity and Wingless signaling pathways

1998 • 642 citations

The role of RhoA in tissue polarity and Frizzled signalling

1997 • 558 citations

Visualization of Gene Expression in Living Adult Drosophila

1996 • 535 citations

Neuronal differentiation in the Drosophila ommatidium

1987 • 532 citations

Regulation and function of the JNK subgroup of MAP kinases

1997 • 484 citations

Systematic gain-of-function genetics in Drosophila

1998 • 467 citations

Making a difference: The role of cell-cell interactions in establishing separate identities for equivalent cells

1992 • 452 citations

MAP Kinases with Distinct Inhibitory Functions Impart Signaling Specificity during Yeast Differentiation

1997 • 434 citations

A Drosophila tissue polarity locus encodes a protein containing seven potential transmembrane domains

1989 • 367 citations

A novel serine kinase activated by rac1/CDC42Hs-dependent autophosphorylation is related to PAK65 and STE20.

1995 • 365 citations

dishevelled is required during wingless signaling to establish both cell polarity and cell identity

1994 • 335 citations

strabismus, a novel gene that regulates tissue polarity and cell fate decisions in Drosophila

1998 • 310 citations

Cell determination strategies in the Drosophila eye

1997 • 308 citations

Ectopic expression of activated Ras1 induces hyperplastic growth and increased cell death in Drosophila imaginal tissues

1998 • 295 citations

NIK is a new Ste20-related kinase that binds NCK and MEKK1 and activates the SAPK/JNK cascade via a conserved regulatory domain

1997 • 257 citations

Drosophila Photoreceptor Axon Guidance and Targeting Requires the Dreadlocks SH2/SH3 Adapter Protein

1996 • 248 citations

Determination of Neuronal Cell Fate: Lessons from the R7 Neuron of Drosophila

1994 • 245 citations

Molecular Cloning of a New Member of the p21-Cdc42/Rac-activated Kinase (PAK) Family

1995 • 240 citations

Human HPK1, a novel human hematopoietic progenitor kinase that activates the JNK/SAPK kinase cascade.

1996 • 230 citations

frizzled regulates mirror-symmetric pattern formation in the Drosophila eye

1995 • 229 citations

Asymmetric Notch activation specifies photoreceptors R3 and R4 and planar polarity in the Drosophila eye

1999 • 224 citations

Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila.

1996 • 215 citations

Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase

1995 • 214 citations

A Drosophila Homolog of the Rac- and Cdc42-Activated Serine/Threonine Kinase PAK Is a Potential Focal Adhesion and Focal Complex Protein That Colocalizes with Dynamic Actin Structures

1996 • 204 citations

A Conserved p38 Mitogen-Activated Protein Kinase Pathway Regulates Drosophila Immunity Gene Expression

1998 • 192 citations

dishevelled is a component of the frizzled signaling pathway in Drosophila

1995 • 176 citations

The genetic control of tissue polarity in Drosophila

1992 • 175 citations

JNK signaling and morphogenesis in Drosophila

1998 • 163 citations

Activation of the c-Jun N-terminal kinase pathway by a novel protein kinase related to human germinal center kinase

1997 • 146 citations

The Drosophila Ste20-related kinase misshapen is required for embryonic dorsal closure and acts through a JNK MAPK module on an evolutionarily conserved signaling pathway

1998 • 142 citations

Mutation of the SPS1-encoded protein kinase of Saccharomyces cerevisiae leads to defects in transcription and morphology during spore formation.

1994 • 119 citations

Distinct roles for the actin and microtubule cytoskeletons in the morphogenesis of epidermal hairs during wing development in Drosophila

1998 • 102 citations

Genes controlling cellular polarity in Drosophila

1993 • 75 citations

misshapen encodes a protein kinase involved in cell shape control in Drosophila

1997 • 51 citations

The Drosophila tissue polarity gene inturned functions prior to wing hair morphogenesis in the regulation of hair polarity and number.

1994 • 50 citations

LET‐23‐mediated signal transduction during Caenorhabditis elegans development

1995 • 29 citations

Archibald Edward Garrod, the reluctant geneticist.

1994 • 28 citations

Deleted Work

1955 • 0 citations