Melanoma–stroma interactions: structural and functional aspects

The Hallmarks of Cancer

2000 • 27,569 citations

Angiogenesis in cancer and other diseases

2000 • 8,734 citations

Isolation of Putative Progenitor Endothelial Cells for Angiogenesis

1997 • 8,673 citations

Cancer: Principles and Practice of Oncology.

1991 • 8,402 citations

Inflammation and cancer: back to Virchow?

2001 • 7,259 citations

Tumors: Wounds That Do Not Heal

1986 • 4,202 citations

Vascular permeability factor/vascular endothelial growth factor, microvascular hyperpermeability, and angiogenesis.

1995 • 3,139 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

The microenvironment of the tumour–host interface

2001 • 2,307 citations

Molecular classification of cutaneous malignant melanoma by gene expression profiling

2000 • 2,011 citations

The Transcriptional Program in the Response of Human Fibroblasts to Serum

1999 • 1,994 citations

Vascular Channel Formation by Human Melanoma Cells in Vivo and in Vitro: Vasculogenic Mimicry

1999 • 1,921 citations

The urokinase-type plasminogen activator system in cancer metastasis: A review

1997 • 1,561 citations

Genomic analysis of metastasis reveals an essential role for RhoC

2000 • 1,449 citations

ECM and Cell Surface Proteolysis: Regulating Cellular Ecology

1997 • 1,311 citations

Barriers to Drug Delivery in Solid Tumors

1994 • 1,064 citations

Myofibroblasts. I. Paracrine cells important in health and disease

1999 • 908 citations

Heterotypic Signaling between Epithelial Tumor Cells and Fibroblasts in Carcinoma Formation

2001 • 554 citations

Molecular cloning of fibroblast activation protein alpha, a member of the serine protease family selectively expressed in stromal fibroblasts of epithelial cancers.

1994 • 522 citations

A new American Joint Committee on Cancer staging system for cutaneous melanoma

2000 • 438 citations

Water transport revisited

1999 • 423 citations

Matrix Metalloproteinases in Human Melanoma

2000 • 414 citations

AUTOCRINE AND PARACRINE REGULATION BY CYTOKINES AND GROWTH FACTORS IN MELANOMA

2000 • 402 citations

Increased Serum Concentration of Angiogenic Factors in Malignant Melanoma Patients Correlates With Tumor Progression and Survival

2001 • 400 citations

The influence of the microenvironment on the malignant phenotype

2000 • 398 citations

Extracellular matrix signaling: integration of form and function in normal and malignant cells

1998 • 360 citations

Morphological and immunophenotypic variations in malignant melanoma

2000 • 345 citations

Antisense targeting of basic fibroblast growth factor and dibroblast growth factor receptor-1 in human melanomas blocks intratumoral angiogenesis and tumor growth

1997 • 290 citations

Cancer invasion and tissue remodeling‐cooperation of protease systems and cell types

1999 • 288 citations

Role of Interleukin-8 in Tumor Growth and Metastasis of Human Melanoma

1999 • 248 citations

Modulation of the Organ Microenvironment for Treatment of Cancer Metastasis

1995 • 244 citations

A secreted FGF-binding protein can serve as the angiogenic switch in human cancer

1997 • 244 citations

Platelet-derived growth factor (PDGF) in oncogenesis: development of a vascular connective tissue stroma in xenotransplanted human melanoma producing PDGF-BB.

1993 • 238 citations

The morphologic characteristics of tumor blood vessels as a marker of tumor progression in primary human uveal melanoma: A matched case-control study

1992 • 235 citations

Morphologic Diversity in Malignant Melanomas

1990 • 200 citations

Vasculogenic Mimicry: How Convincing, How Novel, and How Significant?

2000 • 186 citations

Angiogenesis and tumor progression of melanoma. Quantification of vascularity in melanocytic nevi and cutaneous malignant melanoma.

1992 • 173 citations

Platelet-derived growth factor indirectly stimulates angiogenesis in vitro.

1993 • 157 citations

The Cellular Derivation and the Life Span of the Myofibroblast

1996 • 153 citations

Atypical melanocytic nevi of the genital type with a discussion of reciprocal parenchymal-stromal interactions in the biology of neoplasia

1998 • 141 citations

Prognostic value of MMP-2 immunoreactive protein (72 kD type IV collagenase) in primary skin melanoma

1998 • 136 citations

Tumor progression: Defining the soil round the tumor seed

2001 • 130 citations

Dynamics of intercellular communication during melanoma development

2000 • 125 citations

Transition of horizontal to vertical growth phase melanoma is accompanied by induction of vascular endothelial growth factor expression and angiogenesis

1997 • 118 citations

Differential expression of basic fibroblast growth factor (bFGF) in melanocytic lesions demonstrated by in situ hybridization. Implications for tumor progression.

1994 • 102 citations

Presence of a fluid-conducting meshwork in xenografted cutaneous and primary human uveal melanoma.

2002 • 100 citations

Tumor Progression, Early Diagnosis and Prognosis of Melanoma

1999 • 100 citations

Growth factors and melanomas.

1996 • 99 citations

Prognostic significance of periodic acid-Schiff-positive patterns in primary cutaneous melanoma.

2001 • 90 citations

Microcirculation Architecture of Melanocytic Nevi and Malignant Melanomas of the Ciliary Body and Choroid

1994 • 87 citations

Basic Fibroblast Growth Factor and Ultraviolet B Transform Melanocytes in Human Skin

2001 • 82 citations

Angiogenesis is prognostically important in vertical growth phase melanomas.

1999 • 80 citations

Involvement of CD44 in matrix metalloproteinase-2 regulation in human melanoma cells

1999 • 79 citations

Expression of type VI collagen in uveal melanoma: its role in pattern formation and tumor progression.

1996 • 78 citations

Prognostic value of tumour vascularity in metastatic melanoma and association of blood vessel density with vascular endothelial growth factor expression

1999 • 71 citations

Vascular density in melanoma xenografts correlates with vascular permeability factor expression but not with metastatic potential

1997 • 69 citations

Expression of interleukin-8 detected byin situ hybridization correlates with worse prognosis in primary cutaneous melanoma

1999 • 66 citations

Analysis of the tumor vasculature and metastatic behavior of xenografts of human melanoma cell lines transfected with vascular permeability factor.

1996 • 66 citations

Cytokines and Cancer

1998 • 65 citations

Spatial distribution of tumor-specific monoclonal antibodies in human melanoma xenografts.

1992 • 56 citations

Diagnosis and treatment of uveal melanoma.

1996 • 54 citations

Correlation of ultrasound parameter imaging with microcirculatory patterns in uveal melanomas

1997 • 53 citations

Interactions of Melanocytes and Melanoma Cells With the Microenvironment

1994 • 52 citations

Reassessment of the PAS patterns in uveal melanoma

1997 • 44 citations

High tPA-expression in primary melanoma of the limb correlates with good prognosis

2000 • 44 citations

Tumour metastasis: is tissue an issue?

2001 • 38 citations

Uveal melanoma: detection of extraocular growth with MR imaging and US.

1997 • 36 citations

Evaluation of the Human Choroidal Melanoma Rabbit Model for Studying Microcirculation Patterns with Confocal ICG and Histology

1999 • 30 citations

Parenchymal-Stromal Interactions in Neoplasia: Theoretical considerations and observations in melanocytic neoplasia

1995 • 26 citations

Molecular biology of cutaneous melanoma

2003 • 24 citations

Melanoma and stroma: An interaction of biological and prognostic importance

1996 • 16 citations

Establishment of IPC 227 cells as human xenografts in rabbits: a model of uveal melanoma

2000 • 14 citations

Combining suramin and a chimeric toxin directed to basic fibroblast growth factor receptors increases therapeutic efficacy against human melanoma in an animal model

1999 • 14 citations

Molecular biology of cutaneous melanoma

2015 • 5 citations