Tumor progression: Defining the soil round the tumor seed

THE DISTRIBUTION OF SECONDARY GROWTHS IN CANCER OF THE BREAST.

1889 • 4,920 citations

Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis

2000 • 2,700 citations

The multistep nature of cancer

1993 • 1,872 citations

MMP-9/Gelatinase B Is a Key Regulator of Growth Plate Angiogenesis and Apoptosis of Hypertrophic Chondrocytes

1998 • 1,753 citations

Changing views of the role of matrix metalloproteinases in metastasis

1997 • 1,585 citations

Matrix Metalloproteinases: Biologic Activity and Clinical Implications

2000 • 1,533 citations

ECM and Cell Surface Proteolysis: Regulating Cellular Ecology

1997 • 1,311 citations

MMP-9 Supplied by Bone Marrow–Derived Cells Contributes to Skin Carcinogenesis

2000 • 1,306 citations

Effects of Angiogenesis Inhibitors on Multistage Carcinogenesis in Mice

1999 • 990 citations

Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis

1999 • 937 citations

Multistage carcinogenesis in mouse skin

1992 • 647 citations

Intestinal tumorigenesis is suppressed in mice lacking the metalloproteinase matrilysin

1997 • 612 citations

Matrix metalloproteinases and TIMPs

2000 • 379 citations

Extracellular matrix signaling: integration of form and function in normal and malignant cells

1998 • 360 citations

Modulation of the Organ Microenvironment for Treatment of Cancer Metastasis

1995 • 244 citations

Clinical studies with matrix metalloproteinase inhibitors

1999 • 126 citations

Differing effects of endogenous and synthetic inhibitors of metalloproteinases on intestinal tumorigenesis

1998 • 98 citations

Clinical Progress and the Future of HIV Exceptionalism

1999 • 75 citations

Genetic and epigenetic influences in prostatic carcinogenesis (review).

1998 • 50 citations