Characterization of thrombin receptor expression during vascular lesion formation.

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation

1991 • 2,981 citations

Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

1985 • 2,145 citations

Localization of tissue factor in the normal vessel wall and in the atherosclerotic plaque.

1989 • 1,233 citations

Inhibition of Neointimal Smooth Muscle Accumulation After Angioplasty by an Antibody to PDGF

1991 • 1,081 citations

cDNA sequence and chromosomal localization of human platelet-derived growth factor A-chain and its expression in tumour cell lines

1986 • 786 citations

Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor.

1991 • 722 citations

Cell proliferation in human coronary arteries.

1990 • 532 citations

Thrombin stimulates proliferation of cultured rat aortic smooth muscle cells by a proteolytically activated receptor.

1993 • 506 citations

Platelet-derived growth factor mRNA detection in human atherosclerotic plaques by in situ hybridization.

1988 • 481 citations

PDGF ligand and receptor gene expression during repair of arterial injury.

1990 • 431 citations

Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery.

1989 • 420 citations

Thrombin receptor expression in normal and atherosclerotic human arteries.

1992 • 318 citations

Fundamental principles of in situ hybridization.

1993 • 242 citations

Thrombin stimulates c-sis gene expression in microvascular endothelial cells.

1986 • 235 citations

Selective expression of PDGF A and its receptor during early mouse embryogenesis

1990 • 215 citations

[14] Thrombin

1976 • 214 citations

Kinetics of thrombin receptor cleavage on intact cells. Relation to signaling

1993 • 205 citations

Coagulation factors X, Xa, and protein S as potent mitogens of cultured aortic smooth muscle cells.

1992 • 184 citations

Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.

1992 • 178 citations

Molecular cloning of the rat vascular smooth muscle thrombin receptor. Evidence for in vitro regulation by basic fibroblast growth factor.

1992 • 165 citations

Thrombin-induced events in non-platelet cells are mediated by the unique proteolytic mechanism established for the cloned platelet thrombin receptor.

1992 • 146 citations

The mitogenic effect of thrombin in vascular smooth muscle cells is largely due to basic fibroblast growth factor.

1993 • 111 citations

Thrombosis and the Development of Atherosclerosis: Rokitansky Revisited

1988 • 93 citations

G protein coupling to the thrombin receptor in Chinese hamster lung fibroblasts.

1994 • 78 citations

Induction of vascular smooth muscle cell growth by selective activation of the thrombin receptor Effect of heparin

1992 • 73 citations

A requirement for Ras protein function in thrombin-stimulated mitogenesis in astrocytoma cells.

1993 • 71 citations

Thrombin-induced mitogenesis of vascular SMC is partially mediated by autocrine production of PDGF-AA

1993 • 48 citations

Pathogenesis of Arterial Vascular Disease

2008 • 28 citations

Thrombin Receptor Agonist Peptide Induction of Mitogenesis in CCL39 Cells

1993 • 19 citations