Identification and characterisation of imprinted genes in the mouse

Completion of mouse embryogenesis requires both the maternal and paternal genomes

1984 • 1,529 citations

Development of reconstituted mouse eggs suggests imprinting of the genome during gametogenesis

1984 • 1,402 citations

Targeted Disruption of Decorin Leads to Abnormal Collagen Fibril Morphology and Skin Fragility

1997 • 1,376 citations

Parental imprinting of the mouse H19 gene

1991 • 1,192 citations

Genomic imprinting in mammalian development: a parental tug-of-war

1991 • 1,178 citations

The non-coding Air RNA is required for silencing autosomal imprinted genes

2002 • 1,040 citations

The mouse insulin-like growth factor type-2 receptor is imprinted and closely linked to the Tme locus

1991 • 904 citations

Mutation of the Angelman Ubiquitin Ligase in Mice Causes Increased Cytoplasmic p53 and Deficits of Contextual Learning and Long-Term Potentiation

1998 • 820 citations

Disruption of imprinting caused by deletion of the H19 gene region in mice

1995 • 765 citations

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

1997 • 753 citations

Differential activity of maternally and paternally derived chromosome regions in mice

1985 • 708 citations

Imprinted expression of the Igf2r gene depends on an intronic CpG island

1997 • 578 citations

Abnormal maternal behaviour and growth retardation associated with loss of the imprinted gene Mest

1998 • 571 citations

Ablation of the CDK inhibitor p57Kip2 results in increased apoptosis and delayed differentiation during mouse development.

1997 • 496 citations

A role for the Ras signalling pathway in synaptic transmission and long-term memory

1997 • 474 citations

Regulation of embryonic growth and lysosomal targeting by the imprintedIgf2/Mpr gene

1994 • 471 citations

Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1

2002 • 463 citations

Asymmetric regulation of imprinting on the maternal and paternal chromosomes at the Dlk1-Gtl2 imprinted cluster on mouse chromosome 12

2003 • 460 citations

Mice Lacking Paternally Expressed Pref-1/Dlk1 Display Growth Retardation and Accelerated Adiposity

2002 • 448 citations

A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith–Wiedemann syndrome

1999 • 405 citations

Genomic imprinting of Mash2, a mouse gene required for trophoblast development

1995 • 366 citations

Imprinted microRNA genes transcribed antisense to a reciprocally imprinted retrotransposon-like gene

2003 • 335 citations

Disruption of the mouse Necdin gene results in hypothalamic and behavioral alterations reminiscent of the human Prader-Willi syndrome

2000 • 320 citations

The Dlk1 and Gtl2 genes are linked and reciprocally imprinted

2000 • 304 citations

A mouse model for Prader-Willi syndrome imprinting-centre mutations

1998 • 298 citations

Targeted disruption of the Kvlqt1 gene causes deafness and gastric hyperplasia in mice

2000 • 297 citations

Disruption of the imprinted Grb10 gene leads to disproportionate overgrowth by an Igf2-independent mechanism

2003 • 277 citations

Peg1/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization

1995 • 274 citations

Phenotypic alterations in insulin-deficient mutant mice

1997 • 272 citations

The human GNAS1 gene is imprinted and encodes distinct paternally and biallelically expressed G proteins

1998 • 264 citations

Peg3 imprinted gene on proximal chromosome 7 encodes for a zinc finger protein

1996 • 252 citations

Multiple imprinted sense and antisense transcripts, differential methylation and tandem repeats in a putative imprinting control region upstream of mouse Igf2

1997 • 248 citations

A cluster of oppositely imprinted transcripts at the Gnas locus in the distal imprinting region of mouse chromosome 2

1999 • 244 citations

Maternal imprinting of the mouse Snrpn gene and conserved linkage homology with the human Prader–Willi syndrome region

1992 • 243 citations

Imprinting evolution and the price of silence

2003 • 227 citations

A Novel Imprinted Gene, Encoding a RING Zinc-Finger Protein, and Overlapping Antisense Transcript in the Prader-Willi Syndrome Critical Region

1999 • 225 citations

Identification of tandemly-repeated C/D snoRNA genes at the imprinted human 14q32 domain reminiscent of those at the Prader-Willi/Angelman syndrome region

2002 • 224 citations

Identification of an imprinted U2af binding protein related sequence on mouse chromosome 11 using the RLGS method

1994 • 219 citations

The cell cycle control gene ZAC/PLAGL1 is imprinted--a strong candidate gene for transient neonatal diabetes

2000 • 216 citations

Placental overgrowth in mice lacking the imprinted gene Ipl

2002 • 214 citations

Disruption of the mouse necdin gene results in early post-natal lethality

1999 • 207 citations

The Prader–Willi Syndrome Imprinting Center Activates the Paternally Expressed Murine Ube3a Antisense Transcript but Represses Paternal Ube3a

2001 • 205 citations

Identification of Grf1 on mouse chromosome 9 as an imprinted gene by RLGS–M

1996 • 195 citations

Impaired Activity of the Extraneuronal Monoamine Transporter System Known as Uptake-2 in Orct3/Slc22a3-Deficient Mice

2001 • 193 citations

An imprinted, mammalian bicistronic transcript encodes two independent proteins

1999 • 189 citations

Genomic imprinting is disrupted in interspecific Peromyscus hybrids

1998 • 186 citations

Zac1 (Lot1), a Potential Tumor Suppressor Gene, and the Gene for ɛ-Sarcoglycan Are Maternally Imprinted Genes: Identification by a Subtractive Screen of Novel Uniparental Fibroblast Lines

2000 • 180 citations

Identification of Novel Imprinted Genes in a Genome-Wide Screen for Maternal Methylation

2003 • 177 citations

Parental origin effects in mice

1986 • 175 citations

An imprinted transcript, antisense to Nesp, adds complexity to the cluster of imprinted genes at the mouse Gnas locus

2000 • 160 citations

Paternal Deletion from Snrpn to Ube3a in the Mouse Causes Hypotonia, Growth Retardation and Partial Lethality and Provides Evidence for a Gene Contributing to Prader-Willi Syndrome

1999 • 159 citations

Absence of Decorin Adversely Influences Tubulointerstitial Fibrosis of the Obstructed Kidney by Enhanced Apoptosis and Increased Inflammatory Reaction

2002 • 158 citations

Identification of the Meg1 / Grb10 imprinted gene on mouse proximal chromosome 11, a candidate for the Silver–Russell syndrome gene

1998 • 155 citations

Paternal versus maternal transmission of a stimulatory G-protein α subunit knockout produces opposite effects on energy metabolism

2000 • 153 citations

Inviability of parthenogenones is determined by pronuclei, not egg cytoplasm

1984 • 148 citations

Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprinting

2000 • 140 citations

Identification of a Large Novel Imprinted Gene Cluster on Mouse Proximal Chromosome 6

2003 • 136 citations

Asb4, Ata3, and Dcn Are Novel Imprinted Genes Identified by High-Throughput Screening Using RIKEN cDNA Microarray

2002 • 134 citations

Cooperative action of germ-line mutations in decorin and p53 accelerates lymphoma tumorigenesis

1999 • 133 citations

Small Evolutionarily Conserved RNA, Resembling C/D Box Small Nucleolar RNA, Is Transcribed from PWCR1, a Novel Imprinted Gene in the Prader-Willi Deletion Region, Which Is Highly Expressed in Brain

2000 • 128 citations

Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse

2000 • 128 citations

Mice Lacking a CDK Inhibitor, p57Kip2, Exhibit Skeletal Abnormalities and Growth Retardation

2000 • 123 citations

Absence of Ndn, encoding the Prader-Willi syndrome-deleted gene necdin, results in congenital deficiency of central respiratory drive in neonatal mice.

2003 • 123 citations

Comparative Sequence Analysis of the Imprinted Dlk1–Gtl2 Locus in Three Mammalian Species Reveals Highly Conserved Genomic Elements and Refines Comparison with the Igf2–H19 Region

2001 • 123 citations

Sequence and Comparative Analysis of the Mouse 1-Megabase Region Orthologous to the Human 11p15 Imprinted Domain

2000 • 113 citations

Discovery of Imprinted Transcripts in the Mouse Transcriptome Using Large-Scale Expression Profiling

2003 • 106 citations

An Imprinted Mouse Transcript Homologous to the Human Imprinted in Prader-Willi Syndrome (IPW) Gene

1997 • 105 citations

Igf2 imprinting does not require its own DNA methylation or H19 RNA

1998 • 101 citations

Peg5/Neuronatin is an imprinted gene located on sub-distal chromosome 2 in the mouse

1997 • 98 citations

Genetic and Functional Analysis of neuronatin in Mice with Maternal or Paternal Duplication of Distal Chr 2

1997 • 98 citations

Screening for imprinted genes by allelic message display: Identification of a paternally expressed gene Impact on mouse chromosome 18

1997 • 93 citations

5 The origins of genomic imprinting in mammals

2002 • 93 citations

Identification of Imprinted Loci by Methylation-Sensitive Representational Difference Analysis: Application to Mouse Distal Chromosome 2

1999 • 83 citations

Gatm, a creatine synthesis enzyme, is imprinted in mouse placenta

2003 • 77 citations

Gtl2 lacZ , an insertional mutation on mouse Chromosome 12 with parental origin-dependent phenotype

1996 • 71 citations

Identification of a New Imprinted Gene, Rian, on Mouse Chromosome 12 by Fluorescent Differential Display Screening

2001 • 70 citations

Mit1/Lb9andCopg2, new members of mouse imprinted genes closely linked toPeg1/Mest

2000 • 56 citations

Functional Analysis of Asb-1 Using Genetic Modification in Mice

2001 • 54 citations

Imprinting and Evolution of Two Kruppel-type Zinc-Finger Genes, ZIM3 and ZNF264, Located in the PEG3/USP29 Imprinted Domain

2001 • 49 citations

The Imprinted Oedematous-Small Mutation on Mouse Chromosome 2 Identifies New Roles for Gnas and Gnasxl in Development

2002 • 47 citations

Disruption of mesodermal enhancers forIgf2in the minute mutant

2002 • 42 citations

In vivo analysis of Frat1 deficiency suggests compensatory activity of Frat3

1999 • 40 citations

Two ENU-induced mutations in Rasgrf1 and early mouse growth retardation

2003 • 35 citations

The Oocyte-Specific Methylated Region of the U2afbp-rs/U2af1-rs1 Gene Is Dispensable for Its Imprinted Methylation

2000 • 27 citations

Microarray expression profiling of tissues from mice with uniparental duplications of Chromosomes 7 and 11 to identify imprinted genes

2001 • 22 citations

Mothers Setting Boundaries

2000 • 22 citations