Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

1992 • 3,907 citations

Dnmt3L and the Establishment of Maternal Genomic Imprints

2001 • 1,356 citations

The non-coding Air RNA is required for silencing autosomal imprinted genes

2002 • 1,040 citations

Dnmt3L cooperates with the Dnmt3 family of de novo DNA methyltransferases to establish maternal imprints in mice

2002 • 987 citations

Disruption of imprinting caused by deletion of the H19 gene region in mice

1995 • 765 citations

Altered cell differentiation and proliferation in mice lacking p57KIP2 indicates a role in Beckwith–Wiedemann syndrome

1997 • 753 citations

Deletion of the H19 differentially methylated domain results in loss of imprinted expression of H19 and Igf2

1998 • 641 citations

A maternally methylated CpG island in KvLQT1 is associated with an antisense paternal transcript and loss of imprinting in Beckwith–Wiedemann syndrome

1999 • 405 citations

Loss of imprinting of a paternally expressed transcript, with antisense orientation to K _V LQT1, occurs frequently in Beckwith–Wiedemann syndrome and is independent of insulin-like growth factor II imprinting

1999 • 360 citations

Zp3–cre, a transgenic mouse line for the activation or inactivation of loxP-flanked target genes specifically in the female germ line

1997 • 359 citations

Beckwith-Wiedemann syndrome: imprinting in clusters revisited

2000 • 299 citations

A mouse model for Prader-Willi syndrome imprinting-centre mutations

1998 • 298 citations

Genomic imprinting of p57KIP2, a cyclin–dependent kinase inhibitor, in mouse

1995 • 288 citations

Multiple Mechanisms Regulate Imprinting of the Mouse Distal Chromosome 7 Gene Cluster

1998 • 245 citations

Epigenotype-phenotype correlations in Beckwith-Wiedemann syndrome

2000 • 181 citations

Bidirectional action of the Igf2r imprint control element on upstream and downstream imprinted genes

2001 • 180 citations

Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndrome

2000 • 178 citations

The IPL Gene on Chromosome 11p15.5 is Imprinted in Humans and Mice and is Similar to TDAG51, Implicated in Fas Expression and Apoptosis

1997 • 164 citations

Oppositely imprinted genes p57Kip2 and Igf2 interact in a mouse model for Beckwith-Wiedemann syndrome

1999 • 156 citations

Sequence and functional comparison in the Beckwith-Wiedemann region: implications for a novel imprinting centre and extended imprinting

2000 • 140 citations

H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19

2000 • 139 citations

Sequence conservation and variability of imprinting in the Beckwith-Wiedemann syndrome gene cluster in human and mouse

2000 • 128 citations

A Differentially Methylated Imprinting Control Region within the Kcnq1 Locus Harbors a Methylation-sensitive Chromatin Insulator

2002 • 95 citations

Two Novel Genes in the Center of the 11p15 Imprinted Domain Escape Genomic Imprinting

1999 • 74 citations

Divergently Transcribed Overlapping Genes Expressed in Liver and Kidney and Located in the 11p15.5 Imprinted Domain

1998 • 68 citations

Increased IGF-II protein affectsp57^kip2expressionin vivoandin vitro: Implications for Beckwith–Wiedemann syndrome

2000 • 64 citations

Disruption of an imprinted gene cluster by a targeted chromosomal translocation in mice

2001 • 51 citations

Quantitation of specific transcripts by RT-PCR SNuPE assay.

1994 • 20 citations