Efficiency of Utilization of the Simian Virus 40 Late Polyadenylation Site: Effects of Upstream Sequences

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Detection of specific sequences among DNA fragments separated by gel electrophoresis

1975 • 33,059 citations

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

1983 • 11,902 citations

Current protocols in molecular biology

1988 • 7,584 citations

Purification of Biologically Active Globin Messenger RNA by Chromatography on Oligothymidylic acid-Cellulose

1972 • 6,922 citations

Efficientin vitrosynthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter

1984 • 6,459 citations

Selective extraction of polyoma DNA from infected mouse cell cultures

1967 • 5,357 citations

3′ Non-coding region sequences in eukaryotic messenger RNA

1976 • 3,001 citations

Transcription termination and 3′ processing: the end is in site!

1985 • 1,482 citations

[18] Hybridization of denatured RNA transferred or dotted to nitrocellulose paper

1983 • 1,112 citations

The sequence 5′-AAUAAA-3′ forms part of the recognition site for polyadenylation of late SV40 mRNAs

1981 • 819 citations

High Efficiency DNA-Mediated Transformation of Primate Cells

1983 • 652 citations

Steps in the processing of Ad2 mRNA: Poly(A)+ Nuclear sequences are conserved and poly(A) addition precedes splicing

1978 • 478 citations

Accurate cleavage and polyadenylation of exogenous RNA substrate

1985 • 334 citations

Activation of the SV40 late promoter: Direct effects of T antigen in the absence of viral DNA replication

1984 • 292 citations

Regulation of adenovirus-2 gene expression at the level of transcriptional termination and RNA processing

1981 • 261 citations

The Role of the Poly(A) Sequence in Mammalian Messenger RN

1981 • 254 citations

Stimulation of simian virus 40 late gene expression by simian virus 40 tumor antigen.

1984 • 207 citations

Calcitonin/calcitonin gene-related peptide transcription unit: tissue-specific expression involves selective use of alternative polyadenylation sites.

1984 • 202 citations

Separation and characterization of a poly(A) polymerase and a cleavage/specificity factor required for pre-mRNA polyadenylation

1988 • 195 citations

Mapping the spliced and unspliced late lytic SV40 RNAs

1978 • 193 citations

A 64 kd nuclear protein binds to RNA segments that include the AAUAAA polyadenylation motif

1988 • 187 citations

erg , a Human ets -Related Gene on Chromosome 21: Alternative Splicing, Polyadenylation, and Translation

1987 • 178 citations

The regulated production of mu m and mu s mRNA is dependent on the relative efficiencies of mu s poly(A) site usage and the c mu 4-to-M1 splice.

1989 • 164 citations

Mode of regulation of immunoglobulin μ- and δ-chain expression varies during B-lymphocyte maturation

1984 • 146 citations

A sequence downstream of A-A-U-A-A-A is required for formation of simian virus 40 late mRNA 3' termini in frog oocytes.

1985 • 139 citations

A small nuclear ribonucleoprotein associates with the AAUAAA polyadenylation signal in vitro

1986 • 139 citations

Analysis of an activatable promoter: sequences in the simian virus 40 late promoter required for T-antigen-mediated trans activation.

1985 • 115 citations

Sequences on the 3' side of hexanucleotide AAUAAA affect efficiency of cleavage at the polyadenylation site.

1984 • 113 citations

Transcriptional regulation of the mu-delta heavy chain locus in normal murine B lymphocytes.

1984 • 112 citations

Two proteins crosslinked to RNA containing the adenovirus L3 poly(A) site require the AAUAAA sequence for binding.

1988 • 111 citations

Identification of a sequence element on the 3' side of AAUAAA which is necessary for simian virus 40 late mRNA 3'-end processing.

1985 • 105 citations

Definition of essential sequences and functional equivalence of elements downstream of the adenovirus E2A and the early simian virus 40 polyadenylation sites.

1985 • 102 citations

Isolation and sequence of a cDNA clone which contains the complete coding region of rat phenylalanine hydroxylase. Structural homology with tyrosine hydroxylase, glucocorticoid regulation, and use of alternate polyadenylation sites.

1986 • 89 citations

Changes in RNA titers and polyadenylation during oogenesis and oocyte maturation in Xenopus laevis

1985 • 89 citations

Poly(A) site choice rather than splice site choice governs the regulated production of IgM heavy-chain RNAs.

1988 • 87 citations

The C proteins of heterogeneous nuclear ribonucleoprotein complexes interact with RNA sequences downstream of polyadenylation cleavage sites.

1988 • 86 citations

Genetic maps 1987—A compilation of linkage and restriction maps of genetically studied organisms

1988 • 74 citations

Calcitonin/Calcitonin Gene-Related Peptide Transcription Unit: Tissue-Specific Expression Involves Selective Use of Alternative Polyadenylation Sites

1984 • 73 citations

Sequences on the 3′ Side of Hexanucleotide AAUAAA Affect Efficiency of Cleavage at the Polyadenylation Site

1984 • 72 citations

Analysis of an Activatable Promoter: Sequences in the Simian Virus 40 Late Promoter Required for T-Antigen-Mediated trans Activation

1985 • 67 citations

A functionally redundant downstream sequence in SV40 late pre-mRNA is required for mRNA 3'-end formation and for assembly of a precleavage complex in vitro.

1988 • 64 citations

Mutations downstream of the polyadenylation site of a Xenopus β-globin mRNA affect the position but not the efficiency of 3′ processing

1986 • 63 citations

Sequences Downstream of AAUAAA Signals Affect Pre-mRNA Cleavage and Polyadenylation In Vitro Both Directly and Indirectly

1989 • 61 citations

Identification of a Sequence Element on the 3′ Side of AAUAAA Which Is Necessary for Simian Virus 40 Late mRNA 3′-End Processing

1985 • 59 citations

The Regulated Production of μ_m and μ_s mRNA Is Dependent on the Relative Efficiencies of μ_s Poly(A) Site Usage and the Cμ4-to-M1 Splice

1989 • 57 citations

Requirements for accurate and efficient mRNA 3' end cleavage and polyadenylation of a simian virus 40 early pre-RNA in vitro.

1987 • 56 citations

Definition of Essential Sequences and Functional Equivalence of Elements Downstream of the Adenovirus E2A and the Early Simian Virus 40 Polyadenylation Sites

1985 • 51 citations

Synthesis of two mRNAs by utilization of alternate polyadenylation sites: expression of SV40-mouse immunoglobulin mu chain gene recombinants in Cos monkey cells.

1984 • 42 citations

Fine-structure analysis of the processing and polyadenylation region of the herpes simplex virus type 1 thymidine kinase gene by using linker scanning, internal deletion, and insertion mutations.

1986 • 41 citations

The C Proteins of Heterogeneous Nuclear Ribonucleoprotein Complexes Interact with RNA Sequences Downstream of Polyadenylation Cleavage Sites

1988 • 38 citations

Construction and characterization of CV-1P cell lines which constitutively express the simian virus 40 agnoprotein: alteration of plaquing phenotype of viral agnogene mutants

1986 • 34 citations

Requirements for Accurate and Efficient mRNA 3′ end Cleavage and Polyadenylation of a Simian Virus 40 early pre-RNA In Vitro

1987 • 30 citations

Requirement of A-A-U-A-A-A and adjacent downstream sequences for SV40 early potyadenylation

1986 • 30 citations

A paranuclear extract contains a unique set of viral transcripts late in SV40 infection

1981 • 25 citations

Human Aldolase B Gene: Characterization of the Genomic Aldolase B Gene and Analysis of Sequences Required for Multiple Polyadenylations1

1987 • 23 citations

Deletions in the SV40 late polyadenylation region downstream of the AATAAA mediate similar effects on expression in various mammalian cell lines

1988 • 13 citations

Polyadenylation at a cryptic site in the pBR322 portion of pSV2-neo: prevention of its utilization by the SV40 late poly(A) signal

1987 • 12 citations

Inhibition of polyadenylation of mRNA by gonadotropin releasing hormone

1983 • 11 citations

Variation in the lack of polyadenylation of the rat milk protein mRNAs during the lactation cycle

1985 • 6 citations

Selective amplification in methotrexate-resistant mouse cells of an artificial dihydrofolate reductase transcription unit making use of cryptic splicing and polyadenylation sites.

1984 • 5 citations

New RNA species is produced by alternate polyadenylation following rearrangement associated withCAD gene amplification

1986 • 2 citations

In Vitro Polyadenylation of SV40 Early Pre-mRNA

1987 • 1 citations