Estrogens and Progesterone Promote Persistent CCND1 Gene Activation during G1 by Inducing Transcriptional Derepression via c-Jun/c-Fos/Estrogen Receptor (Progesterone Receptor) Complex Assembly to a Distal Regulatory Element and Recruitment of Cyclin D1 to Its Own Gene Promoter
Data up to Jan 2025
Total Citations Per Year
Abstract
References (72)
Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei
1983 • 11,902 citations
A new method for sequencing DNA.
1977 • 7,941 citations
The nuclear receptor superfamily: The second decade
1995 • 6,929 citations
Cancer Cell Cycles
1996 • 5,379 citations
The retinoblastoma protein and cell cycle control
1995 • 4,873 citations
Gene regulation by steroid hormones
1989 • 3,466 citations
The coregulator exchange in transcriptional functions of nuclear receptors
2000 • 2,219 citations
Cofactor Dynamics and Sufficiency in Estrogen Receptor–Regulated Transcription
2000 • 1,658 citations
Estrogen Receptor-α Directs Ordered, Cyclical, and Combinatorial Recruitment of Cofactors on a Natural Target Promoter
2003 • 1,422 citations
Cyclin D1 provides a link between development and oncogenesis in the retina and breast
1995 • 1,017 citations
Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice
1994 • 982 citations
Specific protection against breast cancers by cyclin D1 ablation
2001 • 930 citations
Estrogen receptor pathways to AP-1
2000 • 867 citations
CDK-Independent Activation of Estrogen Receptor by Cyclin D1
1997 • 698 citations
Mice lacking cyclin D1 are small and show defects in eye and mammary gland development.
1995 • 681 citations
The ubiquitous octamer-binding protein Oct-1 contains a POU domain with a homeo box subdomain.
1988 • 670 citations
Exit from G1 and S Phase of the Cell Cycle Is Regulated by Repressor Complexes Containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF
2000 • 650 citations
Differential Gene Regulation by the Two Progesterone Receptor Isoforms in Human Breast Cancer Cells
2002 • 566 citations
S Phase Activation of the Histone H2B Promoter by OCA-S, a Coactivator Complex that Contains GAPDH as a Key Component
2003 • 528 citations
Unlocking the mechanisms of transcription factor YY1: are chromatin modifying enzymes the key?
1999 • 451 citations
Estrogen-induced Activation of Cdk4 and Cdk2 during G1-S Phase Progression Is Accompanied by Increased Cyclin D1 Expression and Decreased Cyclin-dependent Kinase Inhibitor Association with Cyclin E-Cdk2
1997 • 438 citations
Linking cyclins to transcriptional control
2002 • 434 citations
Opposing Action of Estrogen Receptors α and β on Cyclin D1 Gene Expression
2002 • 426 citations
A Mechanism of Cyclin D1 Action Encoded in the Patterns of Gene Expression in Human Cancer
2003 • 421 citations
Regulation of Transcription Factor YY1 by Acetylation and Deacetylation
2001 • 405 citations
Estrogen induction of the cyclin D1 promoter: Involvement of a cAMP response-like element
1999 • 358 citations
17beta-Estradiol induces cyclin D1 gene transcription, p36D1-p34cdk4 complex activation and p105Rb phosphorylation during mitogenic stimulation of G(1)-arrested human breast cancer cells.
1996 • 344 citations
Minireview: Nuclear Receptor Coactivators—An Update
2002 • 340 citations
The Human Factors YY1 and LSF Repress the Human Immunodeficiency Virus Type 1 Long Terminal Repeat via Recruitment of Histone Deacetylase 1
2000 • 339 citations
p300 and estrogen receptor cooperatively activate transcription via differential enhancement of initiation and reinitiation
1998 • 337 citations
Overexpression of cyclin D mRNA distinguishes invasive and in situ breast carcinomas from non-malignant lesions
1995 • 334 citations
17β-Estradiol Inhibits Apoptosis in MCF-7 Cells, Inducing bcl-2 Expression via Two Estrogen-Responsive Elements Present in the Coding Sequence
2000 • 333 citations
Convergence of Mitogenic Signalling Cascades from Diverse Classes of Receptors at the Cyclin D–Cyclin-Dependent Kinase–pRb-Controlled G1 Checkpoint
1996 • 331 citations
Identification of an estrogen response element upstream of the human c-fosgene that binds the estrogen receptor and the AP-1 transcription factor
1990 • 296 citations
Growth factor, steroid, and steroid antagonist regulation of cyclin gene expression associated with changes in T-47D human breast cancer cell cycle progression.
1993 • 295 citations
c-Myc or Cyclin D1 Mimics Estrogen Effects on Cyclin E-Cdk2 Activation and Cell Cycle Reentry
1998 • 257 citations
Mitotic Phosphorylation of the Oct-1 Homeodomain and Regulation of Oct-1 DNA Binding Activity
1991 • 237 citations
[73] Interaction of protein with DNA in vitro
1987 • 203 citations
Estrogen Regulation of Cyclin D1 Gene Expression in ZR-75 Breast Cancer Cells Involves Multiple Enhancer Elements
2001 • 200 citations
Activation of the cyclin D1 Gene by the E1A-associated Protein p300 through AP-1 Inhibits Cellular Apoptosis
1999 • 185 citations
Convergence of Progesterone with Growth Factor and Cytokine Signaling in Breast Cancer
1998 • 182 citations
Regulation of the retinoblastoma tumor suppressor protein by cyclin/cdks
2001 • 176 citations
The Nuclear Factor YY1 Suppresses the Human Gamma Interferon Promoter through Two Mechanisms: Inhibition of AP1 Binding and Activation of a Silencer Element
1996 • 171 citations
Functional antagonism between YY1 and the serum response factor.
1992 • 168 citations
RETRACTED: Nuclear Receptor Function Requires a TFTC-Type Histone Acetyl Transferase Complex
2002 • 155 citations
A Pure Estrogen Antagonist Inhibits Cyclin E-Cdk2 Activity in MCF-7 Breast Cancer Cells and Induces Accumulation of p130-E2F4 Complexes Characteristic of Quiescence
2000 • 148 citations
Differential Phosphorylation of the Transcription Factor Oct1 During the Cell Cycle
1991 • 145 citations
Characterization of the Physical Interaction between Estrogen Receptor α and JUN Proteins
2001 • 124 citations
AIB1 enhances estrogen-dependent induction of cyclin D1 expression.
2001 • 120 citations
Gene amplification on chromosome band 11q13 and oestrogen receptor status in breast cancer
1990 • 118 citations
Relief of YY1-induced transcriptional repression by protein-protein interaction with the nucleolar phosphoprotein B23.
1994 • 110 citations
Estrogen regulation of proto-oncogenes coding for nuclear proteins.
1993 • 106 citations
Progesterone, in Addition to Estrogen, Induces Cyclin D1 Expression in the Murine Mammary Epithelial Cell, in Vivo*
1997 • 100 citations
Modulation of AP-1 activity by the human progesterone receptor in endometrial adenocarcinoma cells.
1996 • 100 citations
Octamer factors exert a dual effect on the IL-2 and IL-4 promoters.
1994 • 90 citations
A genomic view of estrogen actions in human breast cancer cells by expression profiling of the hormone-responsive transcriptome
2004 • 87 citations
Growth Factor, Steroid, and Steroid Antagonist Regulation of Cyclin Gene Expression Associated With Changes in T-47D Human Breast Cancer Cell Cycle Progression
1993 • 74 citations
Oct-1 Potentiates CREB-Driven Cyclin D1 Promoter Activation via a Phospho-CREB- and CREB Binding Protein-Independent Mechanism
2002 • 72 citations
Two-dimensional gel electrophoresis analyses identify nucleophosmin as an estrogen regulated protein associated with acquired estrogen-independence in human breast cancer cells
1998 • 65 citations
Interaction of Oct-1 with TFIIB
1995 • 64 citations
17 beta-Estradiol overcomes a G1 block induced by HMG-CoA reductase inhibitors and fosters cell cycle progression without inducing ERK-1 and -2 MAP kinases activation.
1996 • 56 citations
The retinoblastoma-interacting zinc-finger protein RIZ is a downstream effector of estrogen action
2000 • 56 citations
Isolation and characterization of the human nucleophosmin/B23 (NPM) gene: identification of the YY1 binding site at the 5' enhancer region
1997 • 53 citations
Functional Antagonism Between YY1 and the Serum Response Factor
1992 • 52 citations
The retinoblastoma-interacting zinc-finger protein RIZ is a downstream effector of estrogen action
2000 • 47 citations
Constitutive overexpression of cyclin D1 does not prevent inhibition of hormone-responsive human breast cancer cell growth by antiestrogens.
1998 • 34 citations
Rb interacts with TAFII250/TFIID through multiple domains
1997 • 25 citations
Differential expression of the human ST5 gene in HeLa-fibroblast hybrid cell lines mediated by YY1: evidence that YY1 plays a part in tumor suppression
1996 • 24 citations
The antiestrogen ICI 182,780 inhibits proliferation of human breast cancer cells by interfering with multiple, sequential estrogen-regulated processes required for cell cycle completion
2000 • 23 citations
Two distinct factors bind to the rabbit uteroglobin TATA-box region and are required for efficient transcription.
1994 • 15 citations
A novel transcriptional element which regulates expression of the CYP2D4 gene by Oct-1 and YY-1 binding
2003 • 13 citations
Two Distinct Factors Bind to the Rabbit Uteroglobin TATA-Box Region and Are Required for Efficient Transcription
1994 • 4 citations