Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

Mammalian G1 cyclins

1993 • 1,990 citations

Cyclin D1 is a nuclear protein required for cell cycle progression in G1.

1993 • 1,605 citations

Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

1988 • 1,440 citations

A novel cyclin encoded by a bcl1-linked candidate oncogene

1991 • 1,286 citations

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

1991 • 1,190 citations

Overexpression of mouse D-type cyclins accelerates G1 phase in rodent fibroblasts.

1993 • 1,057 citations

Regulation of retinoblastoma protein functions by ectopic expression of human cyclins

1992 • 1,031 citations

Human D-type cyclin

1991 • 712 citations

FVB/N: an inbred mouse strain preferable for transgenic analyses.

1991 • 600 citations

Function of a human cyclin gene as an oncogene.

1994 • 471 citations

PRAD1, a candidate BCL1 oncogene: mapping and expression in centrocytic lymphoma.

1991 • 454 citations

Overexpression of cyclin D1 in rat fibroblasts causes abnormalities in growth control, cell cycle progression and gene expression.

1993 • 393 citations

D11S287, a putative oncogene on chromosome 11q13, is amplified and expressed in squamous cell and mammary carcinomas and linked to BCL-1.

1991 • 376 citations

Identification and cloning of two overexpressed genes, U21B31/PRAD1 and EMS1, within the amplified chromosome 11q13 region in human carcinomas.

1992 • 322 citations

Elevated Levels of Cyclin D1 Protein in Response to Increased Expression of Eukaryotic Initiation Factor 4E

1993 • 270 citations

Genomic sequence of hst, a transforming gene encoding a protein homologous to fibroblast growth factors and the int-2-encoded protein.

1987 • 247 citations

Oncogenic activity of cyclin D1 revealed through cooperation with Ha-ras: link between cell cycle control and malignant transformation.

1994 • 219 citations

Interaction Between Human Cyclin A and Adenovirus E1A-Associated p107 Protein

1992 • 216 citations

Elevated levels of cyclin D1 protein in response to increased expression of eukaryotic initiation factor 4E.

1993 • 186 citations

Characterization and Chromosome Assignment of the Human Homolog of int-2, a Potential Proto-Oncogene

1986 • 178 citations

The mouse homolog of the hst/k-FGF gene is adjacent to int-2 and is activated by proviral insertion in some virally induced mammary tumors.

1989 • 160 citations

Characterization and chromosome assignment of the human homolog of int-2, a potential proto-oncogene.

1986 • 149 citations

Association of INT2/HST1 coamplification in primary breast cancer with hormone-dependent phenotype and poor prognosis

1991 • 124 citations

Proliferative breast “disease”. An unresolved diagnostic dilemma

1993 • 45 citations

Insertion mutation of the int-1 and int-2 loci by mouse mammary tumor virus in premalignant and malignant neoplasms from the GR mouse strain

1990 • 31 citations