Vascular endothelial growth factor is a survival factor for renal tubular epithelial cells

Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus: inhibition by overexpression of Bcl-2 and Abl.

1995 • 2,877 citations

Angiogenesis.

1992 • 2,581 citations

Vascular Endothelial Growth Factor Regulates Endothelial Cell Survival through the Phosphatidylinositol 3′-Kinase/Akt Signal Transduction Pathway

1998 • 1,963 citations

High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis

1993 • 1,961 citations

Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: genomic complexity and molecular evolution of the gene

1985 • 1,836 citations

Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factor.

1994 • 1,661 citations

Identification of the KDR tyrosine kinase as a receptor for vascular endothelial cell growth factor

1992 • 1,528 citations

Migration of human monocytes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1

1996 • 1,355 citations

Vascular Endothelial Growth Factor Induces Expression of the Antiapoptotic Proteins Bcl-2 and A1 in Vascular Endothelial Cells

1998 • 996 citations

The Vascular Endothelial Growth Factor Receptor Flt-1 Mediates Biological Activities

1996 • 855 citations

Fetal liver kinase 1 is a receptor for vascular endothelial growth factor and is selectively expressed in vascular endothelium.

1993 • 764 citations

The vascular endothelial growth factor family of polypeptides

1991 • 652 citations

The binding of vascular endothelial growth factor to its receptors is dependent on cell surface-associated heparin-like molecules.

1992 • 495 citations

Characterization of the receptors for vascular endothelial growth factor.

1990 • 310 citations

Epithelioid and fibroblastic rat kidney cell clones: Epidermal growth factor (EGF) receptors and the effect of mouse sarcoma virus transformation

1978 • 296 citations

Expression of vascular endothelial growth factor and its receptors in human renal ontogenesis and in adult kidney

1995 • 287 citations

Vasculotropin/Vascular Endothelial Growth Factor Induces Differentiation in Cultured Osteoblasts

1994 • 285 citations

A new communication system between hepatocytes and sinusoidal endothelial cells in liver through vascular endothelial growth factor and Flt tyrosine kinase receptor family (Flt-1 and KDR/Flk-1).

1994 • 258 citations

Differential Endothelial Migration and Proliferation to Basic Fibroblast Growth Factor and Vascular Endothelial Growth Factor

1996 • 248 citations

Vascular endothelial growth factor up-regulates its receptor fms-like tyrosine kinase 1 (FLT-1) and a soluble variant of FLT-1 in human vascular endothelial cells.

1997 • 225 citations

Vascular Endothelial Growth Factor Induces Nephrogenesis and Vasculogenesis

1999 • 207 citations

VEGF Induces Nuclear Translocation of Flk-1/KDR, Endothelial Nitric Oxide Synthase, and Caveolin-1 in Vascular Endothelial Cells

1999 • 204 citations

Selective Binding of VEGF121 to One of the Three Vascular Endothelial Growth Factor Receptors of Vascular Endothelial Cells

1996 • 200 citations

Heparin modulates the interaction of VEGF165 with soluble and cell associated flk-1 receptors.

1994 • 194 citations

Signalling properties of FLT4, a proteolytically processed receptor tyrosine kinase related to two VEGF receptors.

1994 • 163 citations

Quantification of apoptotic cells with fluorescein isothiocyanate-labeled annexin V in chinese hamster ovary cell cultures treated with cisplatin

1996 • 158 citations

Vasculotropin/Vascular endothelial growth factor is an autocrine growth factor for human retinal pigment epithelial cells cultued in vitro

1995 • 146 citations

Vascular endothelial growth factor and its receptors in normal human testicular tissue

1997 • 143 citations

Receptors of vascular endothelial growth factor/vascular permeability factor (VEGF/VPF) in fetal and adult human kidney

1998 • 142 citations

Differential Binding Characteristics and Cellular Inhibition by Soluble VEGF Receptors 1 and 2

1998 • 135 citations

Uterine smooth muscle cells express functional receptors (flt-1 and KDR) for vascular permeability factor/vascular endothelial growth factor.

1997 • 132 citations

Upregulation of the angiogenic factors PlGF, VEGF and their receptors (Flt-1, Flk-1/KDR) by TSH in cultured thyrocytes and in the thyroid gland of thiouracil-fed rats suggest a TSH-dependent paracrine mechanism for goiter hypervascularization

1997 • 105 citations

The Membrane-bound Form of Heparin-binding Epidermal Growth Factor-like Growth Factor Promotes Survival of Cultured Renal Epithelial Cells

1997 • 104 citations

Novel Human Vascular Endothelial Growth Factor Genes VEGF-B and VEGF-C Localize to Chromosomes 11q13 and 4q34, Respectively

1996 • 103 citations

Protein Tyrosine Kinases Expressed in Glomeruli and Cultured Glomerular Cells: Flt-1 and VEGF Expression in Renal Mesangial Cells

1995 • 97 citations

Identification of a Heparin Binding Peptide on the Extracellular Domain of the KDR VEGF Receptor

1997 • 96 citations

Expression of Vascular Endothelial Growth Factor (VEGF) and VEGF-Receptor Messenger Ribonucleic Acids in the Peri-Implantation Rabbit Uterus1

1997 • 85 citations

Vascular Endothelial Growth Factor Induces Heparin-binding Epidermal Growth Factor-like Growth Factor in Vascular Endothelial Cells

1998 • 77 citations

Effect of vascular endothelial growth factor on growth and differentiation of pancreatic ductal epithelium.

1997 • 73 citations

Induction of VEGF and VEGF receptor gene expression by hypoxia: Divergent regulation in vivo and in vitro

1997 • 68 citations

Two Functional Forms of Vascular Endothelial Growth Factor Receptor-2/Flk-1 mRNA Are Expressed in Normal Rat Retina

1998 • 58 citations

Heparin-binding epidermal growth factor-like growth factor in experimental models of membranous and minimal change nephropathy

1998 • 28 citations

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