Platelet-activating Factor Acetylhydrolases

Platelet-activating factor.

1990 • 904 citations

The growing phospholipase A2 superfamily of signal transduction enzymes

1997 • 811 citations

Anti-inflammatory properties of a platelet-activating factor acetylhydrolase

1995 • 529 citations

Inflammation: Basic Principles and Clinical Correlates

1993 • 518 citations

ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum.

1994 • 498 citations

Miller-Dieker lissencephaly gene encodes a subunit of brain platelet-activating factor

1994 • 473 citations

A specific acetylhydrolase for 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine (a hypotensive and platelet-activating lipid).

1981 • 440 citations

Effect of platelet activating factor-acetylhydrolase on the formation and action of minimally oxidized low density lipoprotein.

1995 • 412 citations

Human plasma platelet-activating factor acetylhydrolase. Association with lipoprotein particles and role in the degradation of platelet-activating factor.

1987 • 404 citations

Human plasma platelet-activating factor acetylhydrolase. Purification and properties.

1987 • 335 citations

Oxidatively modified LDL contains phospholipids with platelet-activating factor-like activity and stimulates the growth of smooth muscle cells.

1995 • 311 citations

Characterization of serum platelet-activating factor (PAF) acetylhydrolase. Correlation between deficiency of serum PAF acetylhydrolase and respiratory symptoms in asthmatic children.

1988 • 285 citations

Platelet-activating factor acetylhydrolase deficiency. A missense mutation near the active site of an anti-inflammatory phospholipase.

1996 • 270 citations

Platelet-activating factor: a phospholipid autacoid with diverse actions

1993 • 253 citations

Platelet-activating factor as a potential retrograde messenger in CA1 hippocampal long-term potentiation

1994 • 251 citations

An Oxidized Derivative of Phosphatidylcholine is a Substrate for the Platelet-Activating Factor Acetylhydrolase from Human Plasma

1989 • 234 citations

Plasma Platelet-activating Factor Acetylhydrolase Is a Secreted Phospholipase A2 with a Catalytic Triad

1995 • 217 citations

Brain acetylhydrolase that inactivates platelet-activating factor is a G-protein-like trimer

1997 • 175 citations

Activities of enzymes that metabolize platelet-activating factor (1-alkyl-2-acetyl-sn-glycero-3-phosphocholine) in neutrophils and eosinophils from humans and the effect of a calcium ionophore

1982 • 174 citations

Purification and characterization of bovine brain platelet-activating factor acetylhydrolase.

1993 • 167 citations

Purification, Properties, Sequencing, and Cloning of a Lipoprotein-Associated, Serine-Dependent Phospholipase Involved in the Oxidative Modification of Low-Density Lipoproteins

1996 • 163 citations

Platelet-activating Factor Acetylhydrolase Increases during Macrophage Differentiation

1989 • 159 citations

Platelet‐activating factor: a mediator for clinicians

1995 • 148 citations

Oxygen radicals inhibit human plasma acetylhydrolase, the enzyme that catabolizes platelet-activating factor.

1994 • 132 citations

Novel leukocyte agonists are released by endothelial cells exposed to peroxide.

1992 • 129 citations

Lissencephaly gene (LIS1) expression in the CNS suggests a role in neuronal migration

1995 • 115 citations

Purification and Characterization of Platelet-activating Factor Acetylhydrolase II from Bovine Liver Cytosol

1995 • 113 citations

The catalytic subunit of bovine brain platelet-activating factor acetylhydrolase is a novel type of serine esterase.

1994 • 113 citations

cDNA Cloning and Expression of Intracellular Platelet-activating Factor (PAF) Acetylhydrolase II

1996 • 111 citations

Mammalian platelet-activating factor acetylhydrolases

1996 • 109 citations

Enhanced Association of Platelet-activating Factor Acetylhydrolase with Lipoprotein (a) in Comparison with Low Density Lipoprotein

1995 • 105 citations

Control of lecithin biosynthesis in erythrocyte membranes

1968 • 105 citations

Serum PAF acetylhydrolase increases during neonatal maturation

1990 • 104 citations

Lipoproteins alter the catalytic behavior of the platelet-activating factor acetylhydrolase in human plasma.

1989 • 104 citations

Platelet-activating factor acetylhydrolase activity in maternal, fetal, and newborn rabbit plasma during pregnancy and lactation.

1988 • 95 citations

Platelet‐activating factor acetylhydrolase activity in human tissues and blood cells

1991 • 94 citations

Cloning and Expression of a cDNA Encoding the β-Subunit (30-kDa Subunit) of Bovine Brain Platelet-activating Factor Acetylhydrolase

1995 • 85 citations

Platelet-Activating Factor Acetylhydrolase Expression and Activity Suggest a Link between Neuronal Migration and Platelet-Activating Factor

1996 • 81 citations

Platelet-activating factor (PAF) stimulates the production of PAF acetylhydrolase by the human hepatoma cell line, HepG2.

1991 • 77 citations

Human platelets stimulated by thrombin produce platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) when the degrading enzyme acetyl hydrolase is blocked

1985 • 76 citations

The platelet-activating factor acetylhydrolase from human erythrocytes. Purification and properties.

1993 • 76 citations

The hormonal regulation of platelet‐activating factor acetylhydrolase activity in plasma

1991 • 68 citations

Increased activity of the platelet-activating factor acetylhydrolase in plasma low density lipoprotein from patients with essential hypertension

1989 • 68 citations

Platelet‐activating factor is a messenger in the electroconvulsive shock‐induced transcriptional activation of c‐fos and zif‐268 in hippocampus

1994 • 65 citations

Platelet-activating factor acetylhydrolase in plasma lipoproteins from patients with ischemic stroke.

1992 • 55 citations

Secretion of Platelet-Activating Factor Acetylhydrolase Following Phorbol Ester-Stimulated Differentiation of HL-60 Cells

1993 • 54 citations

Evidence for the identity of P430 of Photosystem I and chloroplast-bound iron-sulfur protein

1973 • 42 citations

Plasma platelet-activating factor degradation in patients with severe coronary artery disease

1992 • 35 citations

Biosynthesis of paf-acether XIV. Paf-acether output in murine peritoneal macrophages is regulated by the level of acetylhydrolase

1989 • 31 citations

Release of acetylhydrolase from platelets on aggregation with platelet‐activating factor

1988 • 27 citations

Platelet-activating factor acetylhydrolase in plasma lipoproteins of healthy men and women

1991 • 26 citations

Cloning, Expression and Characterization of Plasma Platelet-Activating Factor-Acetylhydrolase from Guinea Pig

1996 • 22 citations