Involvement of the Checkpoint Protein Mec1p in Silencing of Gene Expression at Telomeres in Saccharomyces cerevisiae

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Guide to Yeast Genetics and Molecular Biology

1993 • 2,377 citations

Cell Cycle Checkpoints: Preventing an Identity Crisis

1996 • 2,056 citations

Elevated recombination rates in transcriptionally active DNA

1989 • 1,666 citations

Multifunctional yeast high-copy-number shuttle vectors

1992 • 1,656 citations

Position effect at S. cerevisiae telomeres: Reversible repression of Pol II transcription

1990 • 1,343 citations

Histone H3 and H4 N-termini interact with SIR3 and SIR4 proteins: A molecular model for the formation of heterochromatin in yeast

1995 • 778 citations

Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair.

1994 • 759 citations

A Suppressor of Two Essential Checkpoint Genes Identifies a Novel Protein that Negatively Affects dNTP Pools

1998 • 733 citations

Modifiers of position effect are shared between telomeric and silent mating-type loci in S. cerevisiae

1991 • 700 citations

Components of the Ku-dependent non-homologous end-joining pathway are involved in telomeric length maintenance and telomeric silencing

1998 • 636 citations

Guide to Yeast Genetics and Molecular Biology

1991 • 607 citations

Regulation of RAD53 by the ATM -Like Kinases MEC1 and TEL1 in Yeast Cell Cycle Checkpoint Pathways

1996 • 593 citations

Control of the DNA Damage Checkpoint by Chk1 and Rad53 Protein Kinases Through Distinct Mechanisms

1999 • 535 citations

Spreading of transcriptional represser SIR3 from telomeric heterochromatin

1996 • 523 citations

The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast.

1994 • 502 citations

A RAP1-interacting protein involved in transcriptional silencing and telomere length regulation.

1992 • 480 citations

Relocalization of Telomeric Ku and SIR Proteins in Response to DNA Strand Breaks in Yeast

1999 • 458 citations

Recovery from DNA replicational stress is the essential function of the S-phase checkpoint pathway

1998 • 453 citations

Identification of High-Copy Disruptors of Telomeric Silencing in Saccharomyces cerevisiae

1998 • 452 citations

Yeast Checkpoint Genes in DNA Damage Processing: Implications for Repair and Arrest

1995 • 418 citations

A novel Rap1p-interacting factor, Rif2p, cooperates with Rif1p to regulate telomere length in Saccharomyces cerevisiae.

1997 • 406 citations

DUN1 encodes a protein kinase that controls the DNA damage response in yeast

1993 • 343 citations

MEC1-Dependent Redistribution of the Sir3 Silencing Protein from Telomeres to DNA Double-Strand Breaks

1999 • 332 citations

Time of replication of yeast centromeres and telomeres

1988 • 295 citations

RAP1 and telomere structure regulate telomere position effects in Saccharomyces cerevisiae.

1993 • 283 citations

The budding yeast Rad9 checkpoint protein is subjected to Mec1/Tel1-dependent hyperphosphorylation and interacts with Rad53 after DNA damage

1998 • 274 citations

Overcoming telomeric silencing: a trans-activator competes to establish gene expression in a cell cycle-dependent way.

1994 • 267 citations

Interactions of TLC1 (Which Encodes the RNA Subunit of Telomerase), TEL1, and MEC1 in Regulating Telomere Length in the Yeast Saccharomyces cerevisiae

1999 • 264 citations

SET1, A Yeast Member of theTrithoraxFamily, Functions in Transcriptional Silencing and Diverse Cellular Processes

1997 • 238 citations

MEC1-Dependent Phosphorylation of Rad9p in Response to DNA Damage

1998 • 213 citations

DNA damage checkpoints update: getting molecular

1998 • 194 citations

Telomeric chromatin modulates replication timing near chromosome ends

1999 • 172 citations

RAD53, DUN1 and PDS1 define two parallel G2/M checkpoint pathways in budding yeast

1999 • 165 citations

DNA damage checkpoint in budding yeast

1998 • 162 citations

Mechanisms of silencing in Saccharomyces cerevisiae

1998 • 133 citations

Complete transposition requires four active monomers in the mu transposase tetramer.

1994 • 125 citations

DNA damage triggers disruption of telomeric silencing and Mec1p-dependent relocation of Sir3p

1999 • 115 citations

Interaction between Set1p and checkpoint protein Mec3p in DNA repair and telomere functions

1999 • 98 citations

Dependence of the Regulation of Telomere Length on the Type of Subtelomeric Repeat in the Yeast Saccharomyces cerevisiae

1999 • 98 citations

The recognition of DNA damage

1996 • 81 citations

Genetic Control of Telomere Integrity in Schizosaccharomyces pombe: rad3+ and tel1+ Are Parts of Two Regulatory Networks Independent of the Downstream Protein Kinases chk1+ and cds1+

1999 • 67 citations

Regulation of Telomere Length by Checkpoint Genes inSchizosaccharomyces pombe

1998 • 67 citations

Interaction Between the MEC1-Dependent DNA Synthesis Checkpoint and G1 Cyclin Function in Saccharomyces cerevisiae

1999 • 25 citations

Requirement of Sequences outside the Conserved Kinase Domain of Fission Yeast Rad3p for Checkpoint Control

1999 • 14 citations