Stronger Correlation of bcl‐3 than bcl‐2, bcl‐x_L, Costimulation, or Antioxidants with Adjuvant‐Induced T Cell Survival

bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

1993 • 3,111 citations

T cell tolerance by clonal elimination in the thymus

1987 • 2,248 citations

Determination of lymphocyte division by flow cytometry

1994 • 1,712 citations

Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

1989 • 1,512 citations

CD40-CD40 ligand

2000 • 1,376 citations

CD28 costimulation can promote T cell survival by enhancing the expression of Bcl-xL

1995 • 1,212 citations

Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice

1991 • 1,187 citations

The Vβ-specific superantigen staphylococcal enterotoxin B: Stimulation of mature T cells and clonal deletion in neonatal mice

1989 • 1,095 citations

Visualization of peptide-specific T cell immunity and peripheral tolerance induction in vivo

1994 • 967 citations

Extrathymic tolerance of mature T cells: Clonal elimination as a consequence of immunity

1990 • 904 citations

Virus infection triggers insulin-dependent diabetes mellitus in a transgenic model: Role of anti-self (virus) immune response

1991 • 766 citations

Programmed cell death and extrathymic reduction of Vβ8+CD4+ T cells in mice tolerant to Staphylococcus aureus enterotoxin B

1991 • 675 citations

Peripheral Selection of the T Cell Repertoire

1991 • 666 citations

The oncoprotein Bcl-3 directly transactivates through κB motifs via association with DNA-binding p50B homodimers

1993 • 506 citations

Reactive Oxygen Species Regulate Activation-Induced T Cell Apoptosis

1999 • 485 citations

The candidate proto-oncogene bcl-3 is related to genes implicated in cell lineage determination and cell cycle control

1990 • 469 citations

The Rel/NF-κB signal transduction pathway: introduction

1999 • 436 citations

The candidate proto-oncogene bcl-3 encodes a transcriptional coactivator that activates through NF-kappa B p50 homodimers.

1993 • 416 citations

Cytokine-induced survival of activated T cellsin vitroandin vivo

1998 • 395 citations

Genetic and Physical Mapping of theLpsLocus: Identification of the Toll-4 Receptor as a Candidate Gene in the Critical Region

1998 • 372 citations

Interleukin‐2 receptor common γ‐chain signaling cytokines regulate activated T cell apoptosis in response to growth factor withdrawal: Selective induction of anti‐apoptotic (bcl‐2, bcl‐x_L) but not pro‐apoptotic (bax, bcl‐x_S) gene expression

1996 • 367 citations

The candidate oncoprotein Bcl-3 is an antagonist of pSO/NF-κB-mediated inhibition

1992 • 325 citations

The bcl-3 proto-oncogene encodes a nuclear I kappa B-like molecule that preferentially interacts with NF-kappa B p50 and p52 in a phosphorylation-dependent manner.

1993 • 242 citations

Profound deletion of mature T cells in vivo by chronic exposure to exogenous superantigen.

1993 • 241 citations

Lipopolysaccharide interferes with the induction of peripheral T cell death

1995 • 240 citations

Immunological adjuvants promote activated T cell survival via induction of Bcl-3

2001 • 228 citations

A Natural Immunological Adjuvant Enhances T Cell Clonal Expansion through a CD28-dependent, Interleukin (IL)-2–independent Mechanism

1998 • 220 citations

Peripheral Clonal Elimination of Functional T Cells

1990 • 213 citations

CD4+ T cell effectors can become memory cells with high efficiency and without further division

2001 • 186 citations

Critical Roles for the Bcl-3 Oncoprotein in T Cell–Mediated Immunity, Splenic Microarchitecture, and Germinal Center Reactions

1997 • 179 citations

Infection breaks T-cell tolerance

1992 • 174 citations

Immunological defects in mice with a targeted disruption in Bcl-3.

1997 • 164 citations

Viral and Bacterial Infections Interfere with Peripheral Tolerance Induction and Activate CD8+ T Cells to Cause Immunopathology

1998 • 161 citations

Monoclonal antibodies to murine CD40 define two distinct functional epitopes

1994 • 152 citations

CD28 engagement and proinflammatory cytokines contribute to T cell expansion and long-term survival in vivo.

1997 • 148 citations

Peripheral deletion of autoreactive CD8⁺ T cells in transgenic mice expressing H‐2K^b in the liver

1995 • 138 citations

TERMINATION OF TOLERANCE TO HUMAN GAMMA GLOBULIN IN MICE BY ANTIGEN AND BACTERIAL LIPOPOLYSACCHARIDE (ENDOTOXIN)

1973 • 135 citations

The proto-oncogene bcl-3 encodes an I kappa B protein.

1992 • 116 citations

Ascorbic Acid Is a Potent Inhibitor of Various Forms of T Cell Apoptosis

1999 • 110 citations

Bcl-3 Expression Promotes Cell Survival following Interleukin-4 Deprivation and Is Controlled by AP1 and AP1-Like Transcription Factors

2000 • 103 citations

Bystander Virus Infection Prolongs Activated T Cell Survival

1999 • 90 citations

Peripheral deletion of mature CD8+ antigen-specific T cells after in vivo exposure to male antigen.

1992 • 84 citations

CD40 Activation Boosts T Cell Immunity In Vivo by Enhancing T Cell Clonal Expansion and Delaying Peripheral T Cell Deletion

1999 • 83 citations

In Vivo CD4+ T Cell Tolerance Induction Versus Priming Is Independent of the Rate and Number of Cell Divisions

2000 • 81 citations

B cells are not essential for peripheral T-cell tolerance.

1996 • 65 citations

Peripheral tolerance through clonal deletion of mature CD4⁻CD8⁺ T cells

1992 • 49 citations

Alternative splicing of RNA transcripts encoded by the murine p105 NF-kappa B gene generates I kappa B gamma isoforms with different inhibitory activities.

1994 • 40 citations

Contrasting the Roles of Costimulation and the Natural Adjuvant Lipopolysaccharide During the Induction of T Cell Immunity

2002 • 39 citations

Alternate RNA splicing of murine nfkb1 generates a nuclear isoform of the p50 precursor NF-kappa B1 that can function as a transactivator of NF-kappa B-regulated transcription.

1994 • 24 citations

Clonal expansion but lack of subsequent clonal deletion of bacterial superantigen-reactive T cells in murine retroviral infection.

1994 • 15 citations