Burkitt Lymphoma in the Mouse

World Health Organization Classification of Neoplastic Diseases of the Hematopoietic and Lymphoid Tissues: Report of the Clinical Advisory Committee Meeting—Airlie House, Virginia, November 1997

1999 • 3,357 citations

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1985 • 1,782 citations

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

1982 • 1,746 citations

Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.

1991 • 1,622 citations

Translocation of the c-myc gene into the immunoglobulin heavy chain locus in human Burkitt lymphoma and murine plasmacytoma cells.

1982 • 1,424 citations

A sarcoma involving the jaws in african children

1958 • 1,307 citations

The World Health Organization Classification of Neoplastic Diseases of the Hematopoietic and Lymphoid Tissues

1999 • 820 citations

Marker Band in One Chromosome 14 from Burkitt Lymphomas

1972 • 628 citations

Positive Selection of Natural Autoreactive B Cells

1999 • 574 citations

The c-myc oncogene perturbs B lymphocyte development in Eμ-myc transgenic mice

1986 • 441 citations

Transitional B cells are the target of negative selection in the B cell compartment.

1995 • 352 citations

c-Myc hot spot mutations in lymphomas result in inefficient ubiquitination and decreased proteasome-mediated turnover

2000 • 276 citations

Locus control regions: coming of age at a decade plus

1999 • 232 citations

Mutations in the First Exon Are Associated with Altered Transcription of c- myc in Burkitt Lymphoma

1987 • 228 citations

Plasmacytomagenesis in mice: model of neoplastic development dependent upon chromosomal translocations

1992 • 187 citations

c-myc activation renders proliferation of Epstein-Barr virus (EBV)-transformed cells independent of EBV nuclear antigen 2 and latent membrane protein 1.

1996 • 152 citations

Breakpoints of burkitt's lymphoma t(8;22) translocations map within a distance of 300 kb downstream of MYC

1994 • 86 citations

Inhibition of plasmacytoma development in BALB/c mice by indomethacin.

1985 • 86 citations

The Non-Hodgkin's Lymphomas

1997 • 77 citations

The beta-globin locus control region enhances transcription of but does not confer position-independent expression onto the lacZ gene in transgenic mice.

1996 • 69 citations

IgM receptor-mediated transactivation of the IgH 3′ enhancer couples a novel Elf-1-AP-1 protein complex to the developmental control of enhancer function.

1995 • 69 citations

Atlas Of Mouse Hematopathology

2000 • 62 citations

Deregulation of the proto-oncogene c-myc through t(8;22) translocation in Burkitt's lymphoma

1999 • 60 citations

Insight into Burkitt's Lymphoma from Immunoglobulin Variable Region Gene Analysis

1998 • 54 citations

A T cell controlled molecular pathway regulating the IgH locus: CD40-mediated activation of the IgH 3′ enhancer.

1996 • 39 citations

Absence of a paused transcription complex from the c-myc P2 promoter of the translocation chromosome in Burkitt's lymphoma cells: implication for the c-myc P1/P2 promoter shift.

1993 • 36 citations

Cutting Edge: Ig Heavy Chain 3′ HS1–4 Directs Correct Spatial Position-Independent Expression of a Linked Transgene to B Lineage Cells

1999 • 34 citations

The role of immunoglobulin kappa elements in c-myc activation.

1995 • 32 citations

Differences in the molecular structure of c-myc-activating recombinations in murine plasmacytomas and precursor cells.

1994 • 31 citations

Rapid induction of B-cell lymphomas in mice carrying a human IgH/c-mycYAC

1997 • 28 citations

Post-transcriptional regulation of E2A proteins via lipopolysaccharide and CD40 signaling

2000 • 8 citations