Breakpoints of burkitt's lymphoma t(8;22) translocations map within a distance of 300 kb downstream of MYC

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Genomic sequencing.

1984 • 8,343 citations

The c-myc oncogene driven by immunoglobulin enhancers induces lymphoid malignancy in transgenic mice

1985 • 1,782 citations

Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.

1982 • 1,746 citations

High-Resolution Mapping of Human Chromosome 11 by in Situ Hybridization with Cosmid Clones

1990 • 1,357 citations

The Pathogenesis of Burkitt's Lymphoma

1990 • 477 citations

Clustered arrangement of immunoglobulin λ constant region genes in man

1981 • 379 citations

Transcriptional activation of the translocated c- myc oncogene in Burkitt lymphoma

1983 • 340 citations

Differential Expression of the Translocated and the Untranslocated c- myc Oncogene in Burkitt Lymphoma

1983 • 328 citations

The t(8; 14) chromosomal translocation occurring in B-cell malignancies results from mistakes in V–D–J joining

1986 • 184 citations

Variant (6;15) translocations in murine plasmacytomas involve a chromosome 15 locus at least 72 kb from the c-myc oncogene.

1985 • 180 citations

A common region for proviral DNA integration in MoMuLV-induced rat thymic lymphomas

1983 • 177 citations

A variant translocation places the λ immunoglobulin genes 3′ to the c-myc oncogene in Burkitt's lymphoma

1984 • 145 citations

Chromosome 8 breakpoint far 3′ of the c-myc oncogene in a Burkitt's lymphoma 2;8 variant translocation is equivalent to the murine pvt-1 locus.

1986 • 139 citations

Murine T lymphomas with retroviral inserts in the chromosomal 15 locus for plasmacytoma variant translocations

1985 • 131 citations

Immunoglobulin κ gene expression after stable integration

1989 • 120 citations

V_λ and J_λ‐C_λ gene segments of the human immunoglobulin λ light chain locus are separated by 14 kb and rearrange by a deletion mechanism

1991 • 116 citations

Three breakpoints of variant t(2;8) translocations in Burkitt's lymphoma cells fall within a region 140 kilobases distal from c-myc.

1989 • 106 citations

Variable breakpoints in Burkitt lymphoma cells with chromosomal t(8; 14) translocation separate c-myc and the IgH locus up to several hundred kb

1992 • 103 citations

Synthesis of Kappa Light Chains by Cell Lines Containing an 8;22 Chromosomal Translocation Derived from a Male Homosexual with Burkitt's Lymphoma

1983 • 88 citations

Identification of a human transcription unit affected by the variant chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.

1989 • 85 citations

Burkitt's Lymphoma: A Human Cancer Model

1986 • 83 citations

Mapping chromosomal breakpoints of Burkitt's t(8;14) translocations far upstream of c-myc.

1992 • 80 citations

Burkitt lymphoma cell line carrying a variant translocation creates new DNA at the breakpoint and violates the hierarchy of immunoglobulin gene rearrangement.

1985 • 73 citations

A human chromosome 8 region with abnormalities in B cell, HTLV-I+ T cell and c-myc amplified tumours.

1987 • 72 citations

Cellular oncogene activation

1989 • 47 citations

Distinction between burkitt lymphoma subgroups by monoclonal antibodies: Relationships between antigen expression and type of chromosomal translocation

1984 • 38 citations

B-Cell Maturation Stages of Burkitt's Lymphoma Cell Lines According to Epstein-Barr Virus Status and Type of Chromosome Translocation<xref ref-type="fn" rid="FN2">2</xref>

1987 • 31 citations

Molecular involvement of the pvt-1 locus in a gamma/delta T-cell leukemia bearing a variant t(8;14)(q24;q11) translocation.

1992 • 26 citations

Alternative involvement of two cytogenetically distinguishable breakpoints on chromosome 8 in Burkitt's lymphoma associated translocations

1986 • 21 citations

Translocation t(8;22) in peripheral lymphocytes and established lymphoid cell lines from a patient with Hodgkin's disease followed by acute lymphatic leukemia

1982 • 20 citations

A new variant 15; 16 translocation in mouse plasmacytoma leads to the juxtaposition of c-myc and immunoglobulin lambda.

1991 • 19 citations

Possible Role of Immunoglobulin Recombination Sequences in the Genesis of Variant t(2;8) Translocations of Burkitt Lymphoma

1986 • 5 citations