Evidence That Release of Adenosine Triphosphate From Endothelial Cells During Increased Shear Stress Is Vesicular

Multidrug-resistance gene (P-glycoprotein) is expressed by endothelial cells at blood-brain barrier sites.

1989 • 1,744 citations

The Dynamic Response of Vascular Endothelial Cells to Fluid Shear Stress

1981 • 1,123 citations

Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity

1990 • 618 citations

Volume-regulated chloride channels associated with the human multidrug-resistance P-glycoprotein

1992 • 567 citations

Purification of an N-ethylmaleimide-sensitive protein catalyzing vesicular transport.

1988 • 519 citations

Purinergic signalling: ATP release.

2001 • 505 citations

The cystic fibrosis transmembrane conductance regulator is a dual ATP and chloride channel.

1994 • 354 citations

PURINERGIC INNERVATION OF THE GUINEA‐PIG URINARY BLADDER

1978 • 323 citations

Effect of ATP-sensitive K+ channel regulators on cystic fibrosis transmembrane conductance regulator chloride currents.

1992 • 322 citations

Upregulation of Superoxide Dismutase and Nitric Oxide Synthase Mediates the Apoptosis-Suppressive Effects of Shear Stress on Endothelial Cells

1999 • 299 citations

Antidiabetic sulfonylureas control action potential properties in heart cells via high affinity receptors that are linked to ATP-dependent K+ channels.

1988 • 292 citations

Increased flow‐induced ATP release from isolated vascular endothelial cells but not smooth muscle cells

1991 • 248 citations

A release mechanism for stored ATP in ocular ciliary epithelial cells

1998 • 233 citations

Increased release of ATP from endothelial cells during acute inflammation

1998 • 185 citations

Hepatocellular ATP-binding Cassette Protein Expression Enhances ATP Release and Autocrine Regulation of Cell Volume

1997 • 165 citations

Action of calcium antagonists on multidrug resistant cells

1987 • 144 citations

ABC transporter-facilitated ATP conductive transport

1999 • 139 citations

CFTR Cl- channel and CFTR-associated ATP channel: distinct pores regulated by common gates

1998 • 125 citations

Purified Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Does Not Function as an ATP Channel

1996 • 115 citations

Characterization of CFTR expression and chloride channel activity in human endothelia

1998 • 114 citations

Synergistic effect of acute hypoxia on flow-induced release of ATP from cultured endothelial cells

1995 • 108 citations

Fluorescence-microscopical demonstration of a population of gastro-intestinal nerve fibres with a selective affinity for Quinacrine

1976 • 89 citations

THE INTERACTION OF QUINACRINE WITH ADENINE NUCLEOTIDES

1954 • 83 citations

Specific inhibitors distinguish the chloride channel and drug transporter functions associated with the human multidrug resistance P-glycoprotein.

1993 • 76 citations

An ATP‐sensitive potassium conductance in rabbit arterial endothelial cells.

1995 • 76 citations

Quinacrine fluorescence of Merkel cells in Xenopus laevis

1978 • 62 citations

Introduction: Purinergic transmission

1996 • 37 citations

Inhibitory effects of some purinergic agents on ecto-ATPase activity and pattern of stepwise ATP hydrolysis in rat liver plasma membranes

2000 • 36 citations

Drug resistance and P-glycoprotein expression in endothelial cells of newly formed capillaries induced by tumors.

1998 • 36 citations

Comparative studies of quinacrine-positive neurones in the myenteric plexus of stomach and intestine of guinea-pig, rabbit and rat

1981 • 35 citations

ATP transport and ABC proteins

1996 • 34 citations

ATP-binding cassette proteins as targets for drug discovery

1996 • 30 citations

Depolarization-induced decreases in fluorescence intensity of gastro-intestinal quinacrine-binding nerves

1979 • 27 citations

The inhibitory effects of N-ethylmaleimide, colchicine and cytochalasins on human T-cell functions

1989 • 25 citations

Dilatation of Golgi vesicles by monensin leads to enhanced accumulation of sugar nucleotides

1986 • 10 citations

Quinacrine-staining of neurones, and activity of purine nucleosides and nucleotides in marine and terrestrial invertebrates from several phyla

1992 • 9 citations

Effect of increased flow on release of vasoactive substances from vascular endothelial cells

1994 • 6 citations