I-PpoI, the Endonuclease Encoded by the Group I Intron PpLSU3, Is Expressed from an RNA Polymerase I Transcript

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Laboratory course manual for methods in yeast genetics

1986 • 1,310 citations

A Saccharomyces cerevisiae genomic plasmid bank based on a centromere-containing shuttle vector

1987 • 1,181 citations

SELF-SPLICING OF GROUP I INTRONS

1990 • 852 citations

The cap and poly(A) tail function synergistically to regulate mRNA translational efficiency.

1991 • 795 citations

Starting at the Beginning, Middle, and End: Translation Initiation in Eukaryotes

1997 • 685 citations

Evidence for Trans splicing in trypanosomes

1986 • 486 citations

Identification of a novel Y branch structure as an intermediate in trypanosome mRNA processing: Evidence for Trans splicing

1986 • 354 citations

Mechanisms of Intron Mobility

1995 • 248 citations

Construction of mutant and chimeric genes using the polymerase chain reaction

1989 • 224 citations

A latent intron-encoded maturase is also an endonuclease needed for intron mobility

1989 • 205 citations

Synthesis of large rRNAs by RNA polymerase II in mutants of Saccharomyces cerevisiae defective in RNA polymerase I.

1991 • 174 citations

A mobile group I intron in the nuclear rDNA of physarum polycephalum

1989 • 158 citations

A viral sequence in the 3′-untranslated region mimics a 5′ cap in facilitating translation of uncapped mRNA

1997 • 158 citations

Transcription of herpes simplex virus tk sequences under the control of wild-type and mutant human RNA polymerase I promoters.

1985 • 138 citations

The Assembly of Ribosomes in Yeast

1971 • 122 citations

Mobile introns: definition of terms and recommended nomenclature

1989 • 117 citations

Histone 3' ends: essential and regulatory functions.

1992 • 115 citations

Intron mobility in phage T4 is dependent upon a distinctive class of endonucleases and independent of DNA sequences encoding the intron core: mechanistic and evolutionary implications

1990 • 105 citations

Efficient production of functional mRNA mediated by RNA polymerase I in Trypanosoma brucei

1991 • 91 citations

An approach for isolation of mutants defective in 35S ribosomal RNA synthesis in Saccharomyces cerevisiae.

1991 • 88 citations

Nucleolar and nuclear envelope proteins of the yeast Saccharomyces cerevisiae.

1988 • 86 citations

Turnover of R1 (type I) and R2 (type II) retrotransposable elements in the ribosomal DNA of Drosophila melanogaster.

1992 • 78 citations

An intron in the nuclear ribosomal DNA of Didymium iridis codes for a group I ribozyme and a novel ribozyme that cooperate in self-splicing

1994 • 75 citations

Genes within genes: independent expression of phage T4 intron open reading frames and the genes in which they reside.

1988 • 72 citations

A Mobile Group I Intron from Physarum polycephalum can Insert Itself and Induce Point Mutations in the Nuclear Ribosomal DNA of Saccharomyces cerevisiae

1993 • 62 citations

A family of nuclear homing endonucleases

1993 • 62 citations

In vivo mobility of a group I twintron in nuclear ribosomal DNA of the myxomycete Didymium iridis

1997 • 62 citations

Efficient transcription of a protein-coding gene from the RNA polymerase I promoter in transfected cells.

1985 • 58 citations

The histone mRNA 3′ end is required for localization of histone mRNA to polyribosomes

1992 • 57 citations

Isolation and characterization of temperature-sensitive mutations in RPA190, the gene encoding the largest subunit of RNA polymerase I from Saccharomyces cerevisiae.

1988 • 55 citations

Two group I ribozymes with different functions in a nuclear rDNA intron.

1995 • 54 citations

Synthesis of functional eukaryotic ribosomal RNAs in trans: Development of a novel in vivo rDNA system for dissecting ribosome biogenesis

1997 • 51 citations

Interaction of the intron-encoded mobility endonuclease I-PpoI with its target site.

1993 • 45 citations

Intron 5α of the COXI gene of yeast mitochondrial DNA is a mobile group I intron

1992 • 43 citations

RNA Polymerase I-Promoted HIS4 Expression Yields Uncapped, Polyadenylated mRNA That Is Unstable and Inefficiently Translated in Saccharomyces cerevisiae

1998 • 40 citations

GENETIC ANALYSIS IN THE COLONIA STRAIN OF PHYSARUM POLYCEPHALUM: HETEROTHALLIC STRAINS THAT MATE WITH AND ARE PARTIALLY ISOGENIC TO THE COLONIA STRAIN

1974 • 40 citations

Naegleria nucleolar introns contain two group I ribozymes with different functions in RNA splicing and processing.

1997 • 40 citations

RNA polymerase specificity of mRNA production and enhancer action.

1986 • 38 citations

The pathway to maturity: processing of ribosomal RNA in Saccharomyces cerevisiae.

1995 • 36 citations

Degenerate DNA recognition by I-PpoI endonuclease

1998 • 36 citations

Exon sequence distant from the splic junction are required fo0r efficient self-splicing of theTetrahymena IVA

1992 • 35 citations

Characterization of the self-splicing products of a mobile intron from the nuclear rDNA ofPhysarum polycephalum

1992 • 30 citations

The yeast mitochondrial intron aI5α: associated endonuclease activity and in vivo mobility

1992 • 29 citations

RNA Processing and Expression of an Intron-Encoded Protein in Yeast Mitochondria: Role of a Conserved Dodecamer Sequence

1987 • 25 citations

The Mobile Group I Intron 3α of the Yeast Mitochondrial COXI Gene Encodes a 35-kDa Processed Protein That Is an Endonuclease but Not a Maturase

1995 • 23 citations

Expression of an mRNA coding gene under the control of an RNA polymerase I promoter.

1983 • 16 citations

Tetrahymena ribozyme disrupts rRNA processing in yeast.

1994 • 14 citations

Enhanced self-splicing of Physarum polycephalum intron 3 by a second group I intron.

1995 • 12 citations

Requirements for self-splicing of a group I intron fromPhysarum polycephalum

1994 • 10 citations

Association of transcripts from a group-I intron-containing gene with high sedimentation coefficient particles

1997 • 6 citations

Deleted Work

1955 • 0 citations