Degenerate DNA recognition by I-PpoI endonuclease

Polymer support oligonucleotide synthesis XVIII^1.2): use ofβ-cyanoethyi-N,N-dialkylamino-/N-morpholino phosphoramidite of deoxynucleosides for the synthesis of DNA fragments simplifying deprotection and isolation of the final product

1984 • 840 citations

Group I introns as mobile genetic elements: Facts and mechanistic speculations — a review

1989 • 473 citations

Specificity of substrate recognition by the EcoRI restriction endonuclease.

1975 • 313 citations

Recognition and cleavage site of the intron-encoded omega transposase.

1988 • 262 citations

DNA binding sites for the transcriptional activator/repressor YY1

1995 • 193 citations

Discrimination between DNA sequences by the EcoRV restriction endonuclease

1989 • 124 citations

Thermodynamic origins of specificity in the lac repressor-operator interaction

1985 • 121 citations

Searching sequence space by definably random mutagenesis: improving the catalytic potency of an enzyme.

1990 • 113 citations

Characterization of I-Ppo, an Intron-Encoded Endonuclease That Mediates Homing of a Group I Intron in the Ribosomal DNA of Physarum polycephalum

1990 • 99 citations

The td intron endonuclease I-TevI makes extensive sequence-tolerant contacts across the minor groove of its DNA target.

1993 • 75 citations

Site-Directed Mutagenesis by Double Polymerase Chain Reaction: Megaprimer Method

2003 • 70 citations

In vivo analysis of the Saccharomyces cerevisiae HO nuclease recognition site by site-directed mutagenesis.

1990 • 69 citations

The I-CeuI endonuclease recognizes a sequence of 19 base pairs and preferentially cleaves the coding strand of theChlamydomonas moewusiichloroplast large subunit rRNA gene

1992 • 68 citations

A Mobile Group I Intron from Physarum polycephalum can Insert Itself and Induce Point Mutations in the Nuclear Ribosomal DNA of Saccharomyces cerevisiae

1993 • 62 citations

Characterization of I-Ppo, an intron-encoded endonuclease that mediates homing of a group I intron in the ribosomal DNA of Physarum polycephalum.

1990 • 60 citations

4 Homing Endonucleases

1993 • 50 citations

Substrate Binding and Turnover by the Highly Specific I-PpoI Endonuclease

1996 • 48 citations

Interaction of the intron-encoded mobility endonuclease I-PpoI with its target site.

1993 • 45 citations

The td intron endonuclease I-TevI makes extensive sequence-tolerant contacts across the minor groove of its DNA target.

1993 • 44 citations

A mobile group I intron from Physarum polycephalum can insert itself and induce point mutations in the nuclear ribosomal DNA of saccharomyces cerevisiae.

1993 • 43 citations

Characterization of the cleavage site and the recognition sequence of the I-CreI DNA endonuclease encoded by the chloroplast ribosomal intron of Chlamydomonns reinhardtii

1993 • 40 citations

Complex Recognition Site for the Group I Intron-Encoded Endonuclease I-SceII

1992 • 39 citations

2 Type II Restriction Endonucleases

1993 • 29 citations

Complex recognition site for the group I intron-encoded endonuclease I-SceII.

1992 • 17 citations

Influence of enzyme-substrate contacts located outside the EcoRI recognition site on cleavage of duplex oligodeoxyribonucleotide substrates by EcoRI endonuclease

1992 • 16 citations