Crystal Structure of Human Cyclophilin A Bound to the Amino-Terminal Domain of HIV-1 Capsid

PROCHECK: a program to check the stereochemical quality of protein structures

1993 • 23,689 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

LIGPLOT: a program to generate schematic diagrams of protein-ligand interactions

1995 • 5,246 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

X-PLOR Version 3.1: A System for X-ray Crystallography and NMR

1992 • 3,488 citations

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

Improved Fourier coefficients for maps using phases from partial structures with errors

1986 • 1,897 citations

PROMOTIF—A program to identify and analyze structural motifs in proteins

1996 • 1,046 citations

The MIDAS display system

1988 • 955 citations

The structure of protein-protein recognition sites.

1990 • 825 citations

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

1993 • 802 citations

Specific incorporation of cyclophilin A into HIV-1 virions

1994 • 736 citations

Functional association of cyclophilin A with HIV-1 virions

1994 • 632 citations

A fast algorithm for rendering space-filling molecule pictures

1988 • 616 citations

Structure of the Amino-Terminal Core Domain of the HIV-1 Capsid Protein

1996 • 449 citations

The cyclophilin homolog ninaA is required in the secretory pathway

1991 • 330 citations

Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription

1996 • 327 citations

Crystal structure of dimeric HIV-1 capsid protein

1996 • 323 citations

Prolyl Isomerase: Enzymatic Catalysis of Slow Protein-Folding Reactions

1993 • 307 citations

The cyclophilin homolog NinaA functions as a chaperone, forming a stable complex in vivo with its protein target rhodopsin.

1994 • 305 citations

Substrate specificities of the peptidyl prolyl cis-trans isomerase activities of cyclophilin and FK-506 binding protein: evidence for the existence of a family of distinct enzymes

1990 • 303 citations

Mapping of functionally important residues of a cysteine-histidine box in the human immunodeficiency virus type 1 nucleocapsid protein

1993 • 274 citations

Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy

1991 • 270 citations

The Mechanism of the Eye

1857 • 253 citations

Cloning, expression, and purification of human cyclophilin in Escherichia coli and assessment of the catalytic role of cysteines by site-directed mutagenesis.

1990 • 247 citations

Solution structure of the cyclosporin A/cyclophilin complex by NMR

1993 • 241 citations

Functional domains of the capsid protein of human immunodeficiency virus type 1

1994 • 226 citations

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex

1993 • 217 citations

Cyclophilin: distribution and variant properties in normal and neoplastic tissues.

1986 • 214 citations

Assembly, processing, and infectivity of human immunodeficiency virus type 1 gag mutants

1993 • 187 citations

Cyclophilin A is required for the replication of group M human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus SIV(CPZ)GAB but not group O HIV-1 or other primate immunodeficiency viruses

1996 • 176 citations

Macromolecular interactions in the assembly of HIV and other retroviruses

1994 • 174 citations

Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus (HIV) type 1: interference with HIV protein-cyclophilin A interactions

1995 • 172 citations

Mechanistic studies of peptidyl prolyl cis-trans isomerase: evidence for catalysis by distortion

1990 • 164 citations

Calcium signalling in T cells stimulated by a cyclophilin B-binding protein

1994 • 162 citations

Cyclosporine A-resistant human immunodeficiency virus type 1 mutants demonstrate that Gag encodes the functional target of cyclophilin A

1996 • 144 citations

Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity

1995 • 137 citations

Proline isomerases function during heat shock.

1993 • 130 citations

Evolution of retroposons by acquisition or deletion of retrovirus-like genes.

1991 • 129 citations

The X‐ray structure of a tetrapeptide bound to the active site of human cyclophilin A

1992 • 129 citations

Distinct signals in human immunodeficiency virus type 1 Pr55 necessary for RNA binding and particle formation

1992 • 113 citations

A cyclophilin-related protein involved in the function of natural killer cells.

1993 • 112 citations

Specificity and sequence requirements for interactions between various retroviral Gag proteins

1994 • 106 citations

Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus type 1 (HIV-1): interference with early and late events in HIV-1 replication

1995 • 104 citations

Spontaneous mutations in the human immunodeficiency virus type 1 gag gene that affect viral replication in the presence of cyclosporins

1996 • 100 citations

Cyclophilins: a new family of proteins involved in intracellular folding

1992 • 100 citations

Binding of the human immunodeficiency virus type 1 Gag polyprotein to cyclophilin A is mediated by the central region of capsid and requires Gag dimerization

1996 • 97 citations

Crystal Structure Implies That Cyclophilin Predominantly Catalyzes the Trans to Cis Isomerization^,

1996 • 88 citations

Identification of a Region in the Pr55gag-Polyprotein Essential for HIV-1 Particle Formation

1993 • 86 citations

Crystal structure of cyclophilin A complexed with substrate Ala-Pro suggests a solvent-assisted mechanism of cis-trans isomerization.

1993 • 83 citations

Mechanistic Implication of Crystal Structures of the Cyclophilin−Dipeptide Complexes^,

1996 • 64 citations

A multicopy suppressor of a cell cycle defect in S. pombe encodes a heat shock-inducible 40 kDa cyclophilin-like protein.

1996 • 57 citations

Inhibition of peptidyl-prolyl cis/trans isomerase activity by substrate analog structures: thioxo tetrapeptide-4-nitroanilides

1995 • 46 citations

[Melle⁴]Cyclosporin, a Novel Natural Cyclosporin with anti-HIV Activity: Structural Elucidation, Biosynthesis and Biological Properties

1994 • 44 citations

Solution Conformation of a Cyclophilin-Bound Proline Isomerase Substrate

1994 • 16 citations

Mode of action of SDZ NIM 811, a non-immunosuppressive Cyclosporin A analog with activity against human immunodeficiency virus type 1 (HIV-1)

1995 • 3 citations