Proline isomerases function during heat shock.

A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae.

1989 • 8,705 citations

Protein folding in the cell

1992 • 4,138 citations

Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes

1991 • 4,043 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

The mechanism of action of cyclosporin A and FK506

1992 • 2,127 citations

Identification of calcineurin as a key signalling enzyme in T-lymphocyte activation

1992 • 1,634 citations

Chemistry and Biology of the Immunophilins and Their Immunosuppressive Ligands

1991 • 1,479 citations

The "megaprimer" method of site-directed mutagenesis.

1990 • 1,174 citations

Peptidyl-prolyl cis-trans isomerase is the cyclosporin A-binding protein cyclophilin

1989 • 1,087 citations

A drosophila RNA polymerase II transcription factor binds to the regulatory site of an hsp 70 gene

1984 • 534 citations

Catalysis of protein folding by prolyl isomerase

1987 • 488 citations

The Effects of Cyclosporin A on the Immune System

1985 • 442 citations

Stable binding of Drosophila heat shock factor to head-to-head and tail-to-tail repeats of a conserved 5 bp recognition unit

1989 • 439 citations

Complex Interactions Among Members of an Essential Subfamily of hsp70 Genes in Saccharomyces Cerevisiae

1987 • 358 citations

[9] Construction and use of gene fusions to lacZ (β-galactosidase) that are expressed in yeast

1983 • 342 citations

The cyclophilin homolog ninaA is required in the secretory pathway

1991 • 330 citations

Association of a 59-kilodalton immunophilin with the glucocorticoid receptor complex

1992 • 307 citations

FK 506-binding protein proline rotamase is a target for the immunosuppressive agent FK 506 in Saccharomyces cerevisiae.

1991 • 292 citations

The cyclophilin homolog ninaA is a tissue-specific integral membrane protein required for the proper synthesis of a subset of Drosophila rhodopsins

1991 • 271 citations

Hsp90 chaperonins possess ATPase activity and bind heat shock transcription factors and peptidyl prolyl isomerases.

1993 • 245 citations

Hsp56: a novel heat shock protein associated with untransformed steroid receptor complexes.

1990 • 221 citations

Isomerase and Chaperone Activity of Prolyl Isomerase in the Folding of Carbonic Anhydrase

1992 • 206 citations

Calcineurin mediates inhibition by FK506 and cyclosporin of recovery from α-factor arrest in yeast

1992 • 195 citations

Catalysis of protein folding by cyclophilins from different species

1991 • 183 citations

Yeast cyclophilin: isolation and characterization of the protein, cDNA and gene

1989 • 142 citations

Characterization of high molecular weight FK-506 binding activities reveals a novel FK-506-binding protein as well as a protein complex.

1992 • 113 citations

Cyclophilins: a new family of proteins involved in intracellular folding

1992 • 100 citations

FKB1 encodes a nonessential FK 506-binding protein in Saccharomyces cerevisiae and contains regions suggesting homology to the cyclophilins.

1991 • 98 citations

Positive and negative regulation of basal expression of a yeast HSP70 gene.

1989 • 72 citations

A yeast cyclophilin gene essential for lactate metabolism at high temperature.

1992 • 70 citations

A second cyclophilin-related gene inSaccharomyces cerevisiae

1990 • 65 citations

Yeast FKBP-13 is a membrane-associated FK506-binding protein encoded by the nonessential gene FKB2.

1992 • 55 citations

Opposing regulatory functions of positive and negative elements in UASG control transcription of the yeast GAL genes.

1990 • 43 citations

The yeast cyclophilin multigene family: purification, cloning and characterization of a new isoform

1992 • 40 citations

Positive and Negative Regulation of Basal Expression of a Yeast HSP70 Gene

1989 • 30 citations

Opposing Regulatory Functions of Positive and Negative Elements in UAS_g Control Transcription of the Yeast GAL Genes

1990 • 19 citations