Structure of the Amino-Terminal Core Domain of the HIV-1 Capsid Protein

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

[6] Use of T7 RNA polymerase to direct expression of cloned genes

1990 • 6,681 citations

Investigation of exchange processes by two-dimensional NMR spectroscopy

1979 • 4,720 citations

Protein Structure Comparison by Alignment of Distance Matrices

1993 • 3,989 citations

Gradient-tailored excitation for single-quantum NMR spectroscopy of aqueous solutions

1992 • 3,627 citations

NMR View: A computer program for the visualization and analysis of NMR data

1994 • 3,061 citations

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

1986 • 2,918 citations

Raster3D Version 2.0. A program for photorealistic molecular graphics

1994 • 2,515 citations

The 13C Chemical-Shift Index: A simple method for the identification of protein secondary structure using 13C chemical-shift data

1994 • 2,121 citations

The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy

1992 • 2,028 citations

Relationship between nuclear magnetic resonance chemical shift and protein secondary structure

1991 • 1,888 citations

Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A

1984 • 1,670 citations

Elucidation of cross relaxation in liquids by two-dimensional N.M.R. spectroscopy

1980 • 1,490 citations

Structure of a human common cold virus and functional relationship to other picornaviruses

1985 • 1,419 citations

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

1989 • 1,414 citations

Three-Dimensional Structure of Poliovirus at 2.9 Å Resolution

1985 • 1,253 citations

Clean TOCSY for proton spin system identification in macromolecules

1988 • 1,128 citations

Empirical correlation between protein backbone conformation and C.alpha. and C.beta. 13C nuclear magnetic resonance chemical shifts

1991 • 1,072 citations

Correlating backbone amide and side chain resonances in larger proteins by multiple relayed triple resonance NMR

1992 • 1,012 citations

Analysis and prediction of the different types of β-turn in proteins

1988 • 962 citations

The MIDAS display system

1988 • 955 citations

The importance of not saturating water in protein NMR. Application to sensitivity enhancement and NOE measurements

1993 • 891 citations

Overcoming the overlap problem in the assignment of proton NMR spectra of larger proteins by use of three-dimensional heteronuclear proton-nitrogen-15 Hartmann-Hahn-multiple quantum coherence and nuclear Overhauser-multiple quantum coherence spectroscopy: application to interleukin 1.beta.

1989 • 840 citations

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1.

1989 • 831 citations

STRUCTURE-BASED INHIBITORS OF HIV-1 PROTEASE

1993 • 822 citations

Gradient-Enhanced Triple-Resonance Three-Dimensional NMR Experiments with Improved Sensitivity

1994 • 814 citations

Human immunodeficiency virus type 1 Gag protein binds to cyclophilins A and B

1993 • 802 citations

Efficient computation of three-dimensional protein structures in solution from nuclear magnetic resonance data using the program DIANA and the supporting programs CALIBA, HABAS and GLOMSA

1991 • 787 citations

Specific incorporation of cyclophilin A into HIV-1 virions

1994 • 736 citations

Improved 3D triple-resonance NMR techniques applied to a 31 kDa protein

1992 • 732 citations

Structural basis of the activation and action of trypsin

1978 • 669 citations

Tomato bushy stunt virus at 2.9 Å resolution

1978 • 668 citations

Backbone 1H and 15N resonance assignments of the N-terminal SH3 domain of drk in folded and unfolded states using enhanced-sensitivity pulsed field gradient NMR techniques

1994 • 648 citations

Functional association of cyclophilin A with HIV-1 virions

1994 • 632 citations

A fast algorithm for rendering space-filling molecule pictures

1988 • 616 citations

Correlation of Backbone Amide and Aliphatic Side-Chain Resonances in 13C/15N-Enriched Proteins by Isotropic Mixing of 13C Magnetization

1993 • 591 citations

1H1H correlation via isotropic mixing of 13C magnetization, a new three-dimensional approach for assigning 1H and 13C spectra of 13C-enriched proteins

1990 • 580 citations

Three-dimensional triple-resonance NMR Spectroscopy of isotopically enriched proteins

2011 • 561 citations

ICOSAHEDRAL RNA VIRUS STRUCTURE

1989 • 532 citations

Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: implications for membrane association and assembly.

1996 • 478 citations

Structure of crystalline α-chymotrypsin

1968 • 435 citations

The three-dimensional structure of the bacterial virus MS2

1990 • 392 citations

Heteronuclear three-dimensional nmr spectroscopy. A strategy for the simplification of homonuclear two-dimensional NMR spectra

1988 • 382 citations

Structure of southern bean mosaic virus at 2.8 Å resolution

1980 • 371 citations

Chymotrypsinogen: 2,5-Å crystal structure, comparison with α-chymotrypsin, and implications for zymogen activation

1970 • 345 citations

Improved efficiency of protein structure calculations from NMR data using the program DIANA with redundant dihedral angle constraints

1991 • 335 citations

Cyclophilin A is required for an early step in the life cycle of human immunodeficiency virus type 1 before the initiation of reverse transcription

1996 • 327 citations

The gag gene products of human immunodeficiency virus type 1: alignment within the gag open reading frame, identification of posttranslational modifications, and evidence for alternative gag precursors

1988 • 310 citations

Four-Dimensional Heteronuclear Triple-Resonance NMR Spectroscopy of Interleukin-1β in Solution

1990 • 308 citations

Gag proteins of the highly replicative MN strain of human immunodeficiency virus type 1: posttranslational modifications, proteolytic processings, and complete amino acid sequences

1992 • 273 citations

Three-dimensional Structure of the Human Immunodeficiency Virus Type 1 Matrix Protein

1994 • 267 citations

Role of the major homology region of human immunodeficiency virus type 1 in virion morphogenesis

1994 • 251 citations

Identification of human immunodeficiency virus type 1 Gag protein domains essential to membrane binding and particle assembly

1994 • 251 citations

Conformational equilibria in α- and δ-chymotrypsin

1972 • 250 citations

Crystal structure of bovine trypsinogen at 1·8 Å resolution

1977 • 242 citations

Solution structure of the cyclosporin A/cyclophilin complex by NMR

1993 • 241 citations

Functional domains of the capsid protein of human immunodeficiency virus type 1

1994 • 226 citations

X-ray structure of a decameric cyclophilin-cyclosporin crystal complex

1993 • 217 citations

Assembly of recombinant human immunodeficiency virus type 1 capsid protein in vitro

1992 • 217 citations

Assembly, processing, and infectivity of human immunodeficiency virus type 1 gag mutants

1993 • 187 citations

Increased Resolution and Improved Spectral Quality in Four-Dimensional 13C/13C-Separated HMQC-NOESY-HMQC Spectra Using Pulsed Field Gradients

1993 • 187 citations

Crystal structure of SIV matrix antigen and implications for virus assembly

1995 • 184 citations

Macromolecular interactions in the assembly of HIV and other retroviruses

1994 • 174 citations

Structure of bovine trypsinogen at 1.9 Å resolution

1977 • 174 citations

Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus (HIV) type 1: interference with HIV protein-cyclophilin A interactions

1995 • 172 citations

Detection of nuclear Overhauser effects between degenerate amide proton resonances by heteronuclear three-dimensional NMR spectroscopy

1990 • 162 citations

The crystal structure of bluetongue virus VP7

1995 • 156 citations

Structure of Satellite tobacco necrosis virus at 3.0 Å resolution

1982 • 154 citations

Linker insertion mutations in the human immunodeficiency virus type 1 gag gene: effects on virion particle assembly, release, and infectivity

1995 • 137 citations

Improved three-dimensional1H−13C−1H correlation spectroscopy of a13C-labeled protein using constant-time evolution

1991 • 130 citations

Measurement of fast proton exchange rates in isotopically labeled compounds

1993 • 127 citations

Structural similarity between the p17 matrix protein of HIV-1 and interferon-γ

1994 • 126 citations

Distinct signals in human immunodeficiency virus type 1 Pr55 necessary for RNA binding and particle formation

1992 • 113 citations

Specificity and sequence requirements for interactions between various retroviral Gag proteins

1994 • 106 citations

Mode of action of SDZ NIM 811, a nonimmunosuppressive cyclosporin A analog with activity against human immunodeficiency virus type 1 (HIV-1): interference with early and late events in HIV-1 replication

1995 • 104 citations

Spontaneous mutations in the human immunodeficiency virus type 1 gag gene that affect viral replication in the presence of cyclosporins

1996 • 100 citations

An enhanced-sensitivity pure absorption gradient 4D 15N, 13C-edited NOESY experiment

1993 • 97 citations

Analysis and Localization of Cyclophilin A Found in the Virions of Human Immunodeficiency Virus Type 1 MN Strain

1995 • 97 citations

Hydrophobic Interactions Control Zymogen Activation in the Trypsin Family of Serine Proteases

1996 • 91 citations

Identification of a Region in the Pr55gag-Polyprotein Essential for HIV-1 Particle Formation

1993 • 86 citations

Phenotypic characterization of insertion mutants of the human immunodeficiency virus type 1 Gag precursor expressed in recombinant baculovirus-infected cells

1994 • 81 citations

Conformation of the high pH form of chymotrypsin

1969 • 69 citations

Antiviral agents targeted to interact with viral capsid proteins and a possible application to human immunodeficiency virus.

1988 • 68 citations

Crystal structure of the top domain of African horse sickness virus VP7: comparisons with bluetongue virus VP7

1996 • 62 citations

A detailed structural comparison between the charge relay system in chymotrypsinogen and in α-chymotrypsin

1976 • 59 citations

Assembly-defective point mutants of the human immunodeficiency virus type 1 Gag precursor phenotypically expressed in recombinant baculovirus-infected cells

1993 • 59 citations

A possible homology between immunodeficiency virus p24 core protein and picornaviral VP2 coat protein: prediction of HIV p24 antigenic sites.

1989 • 53 citations

Characterization of HIV‐1 p24 self‐association using analytical affinity chromatography

1992 • 50 citations

Measurement of intrinsic exchange rates of amide protons in a 15N-labeled peptide

1995 • 46 citations

Mechanism of charge compensation and impairment of co-operative functions in haemoglobin Tacoma (Arg B12(30)β → ser)

1977 • 45 citations

Preparation and crystallization of a human immunodeficiency virus p24-Fab complex.

1990 • 44 citations

Location of epitopes on the major core protein p24 of human immunodeficiency virus

1990 • 31 citations

[21] Determining confidence intervals for parameters derived from analysis of equilibrium analytical ultracentrifugation data

1994 • 30 citations

Structure of Crystalline α-Chymotrypsin II. A Preliminary Report Including a Hypothesis for the Activation Mechanism

1989 • 26 citations

Clonal analysis of murine b cell response to the human immunodeficiency virus type 1 (HIV1)-gag p17 and p25 antigens

1992 • 25 citations

Spectral Analysis and Tryptic Susceptibility as Probes of HIV-1 Capsid Protein Structure

1994 • 21 citations

Structure determination and refinement of homotetrameric hemoglobin from Urechis caupo at 2.5 Å resolution

1992 • 18 citations

The gag proteins of human immunodeficiency virus type 1: mechanisms of virus assembly and possibilities for interference

1994 • 8 citations